Human PRAM1 cDNA Clone Expression Plasmid – Cat# MBS1273361

PRAM1 cDNA Clone – PML-RARA Regulated Adaptor Molecule 1 (Human)

Name: PRAM1 cDNA Clone; Human; MyBioSource
Brand: MyBioSource
SKU: MBS1273361
Price: 760 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1273361

MBS1273361 is a cDNA clone targeting PRAM1. More details

$760 / 0.01 mg Plasmid + 0.2 mL Glycerol-Stock +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

PRAM1, cDNA Clone

Full Product Name

PRAM1 cDNA Clone

Product Gene Name

PRAM1 cdna clone

Sequence

atggcccatc acctgcctgc agccatggag aaccatcagg acttccggag catcaaagca aagttccagg cctctcagcc ggagcccagc gacctgccca aaaaacctcc gaagcctgag tttggtaaac tgaagaagtt ctcccagcct gagctaagcg agcaccccaa gaaggccccg ctgcctgagt ttggtgcagt gtccttgaag cccccgccgc ctgaggtcac tgacctcccc aagaagcccc cgccgcctga ggtcactgac ctccccaaga agcccccgcc gcctgaggtc actgacctcc ccaagaagcc cccgccgcct gaggtcactg acctccccaa gaagccgtcc aaactggagt tgagtgacct ctccaagaag ttcccacagc tgggggccac tccgtttcca aggaagcccc tgcagcctga ggtcggtgag gcccctttga aggcctcgct gccggagcct ggtgcgccgg cccggaaacc cctgcagccc gacgaactca gtcaccccgc cagacccccc tccgaaccca aatccggcgc attccccagg aagctctggc aacccgaggc cggtgaggct accccgaggt ccccgcagcc tgagttgagt acctttccca agaagcctgc gcagcctgag ttcaacgtgt accccaaaaa gcctccgcag cctcaggtcg gtggcctccc taagaagtcc gtgccgcagc ctgagttcag cgaggccgct cagactcccc tctggaagcc tcagtccagc gagccgaagc gcgactccag cgcctttccc aaaaaggcct cccagcctcc gctgagtgac tttcccaaga agcctccgca gcctgagctt ggggacctca ccaggacctc ctcagagccc gaagtcagcg tgcttcccaa gaggccgcgg ccggccgaat tcaaagcgct ctccaagaag cccccgcagc ccgagctggg cggcctcccc aggacctcct cagagcccga gttcaactca ctccccagga agctgctgca gccggagcgc cgggggccac cccgcaagtt ctcacagcct gagcccagcg ctgtcctcaa gagacacccg cagcctgagt tcttcggtga tctccctcga aagcctccac tccccagctc cgcttccgag agctcactgc ctgcggccgt ggccggcttc agctcccggc acccgctcag ccctgggttt ggagccgctg ggacaccccg ctggaggtca ggaggcctgg ttcacagtgg aggggccagg ccaggcctca gacccagcca tccaccccgg cggaggcctc tgccccctgc cagcagcctg ggacaccctc cagccaagcc cccgctgccc ccggggcccg tggatatgca gagctttcgg agaccctctg cagcatccat agatctacgg aggacccgct cggccgctgg gctccacttc caggaccgac agcctgaaga catcccgcag gtcccagatg agatctacga gctgtatgac gatgtggaac ccagagatga ctccagcccc agccccaagg gcagagatga agcgccctca gttcagcaag ccgccaggag gccaccacaa gacccagcgc tcaggaagga gaaggatccc cagccacagc agttgccacc catggaccca aagttgctga agcagctgag gaaggcagag aaggccgaga gggagttccg gaagaagttc aagtttgaag gggagatcgt ggttcacacg aagatgatga tcgaccccaa cgctaagaca cgtcgcgggg gtggcaagca cctcgggatc cggcgcgggg agatcctgga ggtgatcgag ttcaccagca atgaggagat gctgtgccgg gaccccaaag gcaaatatgg ctacgtgccc agaacagcgc tcctgcccct ggagacggag gtgtacgatg atgtcgactt ctgcgatccc ctggaaaacc aaccactccc cctgggacgg taa

Molecular Weight

73,969 Da

OMIM

606466

Vector

Please Inquire

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of PRAM1 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for PRAM1. It may not necessarily be applicable to this product.

NCBI GI #

20380057

NCBI GeneID

84106

NCBI Accession #

BC028012

UniProt Secondary Accession #

Q8N6W7

UniProt Related Accession #

Q96QH2

NCBI Official Full Name

Homo sapiens PML-RARA regulated adaptor molecule 1, mRNA

NCBI Official Synonym Full Names

PML-RARA regulated adaptor molecule 1

NCBI Official Symbol

PRAM1

NCBI Official Synonym Symbols

PRAM-1; PML-RAR

UniProt Protein Name

PML-RARA-regulated adapter molecule 1

Protein Family

PML-RARA-regulated adapter molecule

UniProt Gene Name

PRAM1

UniProt Synonym Gene Names

PRAM; PRAM-1

UniProt Entry Name

PRAM_HUMAN

NCBI Protein Information

PML-RARA-regulated adapter molecule 1

NCBI Summary for PRAM1

The protein encoded by this gene is similar to FYN binding protein (FYB/SLAP-130), an adaptor protein involved in T cell receptor mediated signaling. This gene is expressed and regulated during normal myelopoiesis. The expression of this gene is induced by retinoic acid and is inhibited by the expression of PML-RARalpha, a fusion protein of promyelocytic leukemia (PML) and the retinoic acid receptor-alpha (RARalpha). [provided by RefSeq, Jul 2008]

UniProt Comments for PRAM1

PRAM1: May be involved in myeloid differentiation. May be involved in integrin signaling in neutrophils. Binds to PtdIns(4)P. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Adaptor/scaffold

Chromosomal Location of Human Ortholog: 19p13.2

Molecular Function: protein binding

Biological Process: integrin-mediated signaling pathway; regulation of neutrophil degranulation

Research Articles on PRAM1

1. Our results show that the pretreatment PML-RARA molecular burden could therefore be used to improve risk stratification in order to develop more individualized treatment regimens for high-risk APL cases.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Diseases associated with PRAM1 cdna clone

Disease Name	Pubmed Publications
Neoplasms Antibodies	>6 publications with PRAM1 and Neoplasms
Leukemia, Myeloid Antibodies	>6 publications with PRAM1 and Leukemia, Myeloid
Cell Transformation, Neoplastic Antibodies	>2 publications with PRAM1 and Cell Transformation, Neoplastic
Drug Toxicity Antibodies	>1 publications with PRAM1 and Drug Toxicity
Cardiovascular Diseases Antibodies	>1 publications with PRAM1 and Cardiovascular Diseases

Organs/Tissues associated with PRAM1 cdna clone

Organ/Tissue Name	Pubmed Publications
Blood Antibodies	>3 publications with PRAM1 and Blood
Bone Antibodies	>2 publications with PRAM1 and Bone
Bone Marrow Antibodies	>2 publications with PRAM1 and Bone Marrow