Human PRELP cDNA Clone Expression Plasmid – Cat# MBS1270278

PRELP cDNA Clone – Proline/Arginine-Rich End Leucine-Rich Repeat Protein (Human)

Name: PRELP cDNA Clone; Human; MyBioSource
Brand: MyBioSource
SKU: MBS1270278
Price: 235 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1270278

MBS1270278 is a cDNA clone targeting PRELP. More details

$235 / 0.01 mg Plasmid + 0.2 mL Glycerol-Stock +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

PRELP, cDNA Clone

Full Product Name

PRELP cDNA Clone

Product Gene Name

PRELP cdna clone

Sequence

atgaggtcac ccctctgctg gctcctccca cttctcatct tggcctcagt ggcccaaggc cagccaacaa gacgaccaag acccgggact gggcccgggc gcagacccag gcccaggccc aggcccacac ccagctttcc tcagcctgat gaaccagcag agccaacaga cctgcctcct cccctccctc caggccctcc atctatcttc cctgactgtc cccgcgaatg ctactgcccc cctgatttcc catctgccct ctactgtgat agccgcaacc tgcgaaaggt ccctgtcatc ccgccccgca tccattacct ctatctccag aacaacttca tcactgagct cccggtggag tccttccaga atgccacagg cctgcgatgg attaacctgg acaacaaccg aatccgcaag atagaccaga gggtgctgga gaaactgccc ggcctggtgt tcctctacat ggagaagaac cagttggaag aggtcccctc ggccctgccc cggaacctgg agcagctgag gctgagccag aaccacatct ccagaatccc gcctggtgtc ttcagcaagc tggagaacct gctgctcctg gatctccagc acaacaggct gagcgacggc gtcttcaagc ccgacacctt ccatggcctc aagaacctca tgcagctcaa cctggcccac aacatcctga gaaagatgcc gcccagggtc cccaccgcca ttcaccagct ctacctggac agtaacaaga ttgagaccat ccctaacgga tacttcaaga gctttcccaa tcttgccttc attcggctta actacaacaa gctgacagac aggggactcc ccaagaactc ctttaatatc tccaacctgc ttgtgctcca cctgtcccac aacaggatca gcagtgtgcc cgccatcaac aacaggctgg aacacctgta cctcaacaac aatagcatcg agaaaatcaa cggaacccag atttgcccca acgacctagt ggcgttccat gacttctcct cggacctgga gaacgtgcca cacctgcgct acctgcggct ggatggaaac tacttgaagc cgcccatccc gctggacctc atgatgtgct tccgcctcct gcagtccgtg gtcatctag

Molecular Weight

43,810 Da

OMIM

601914

Vector

pENTR223.1 or pUC

Clone Sequence Report

Provided with product shipment

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of PRELP cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for PRELP. It may not necessarily be applicable to this product.

NCBI GI #

21618472

NCBI GeneID

5549

NCBI Accession #

BC032498

UniProt Secondary Accession #

Q6FG38

UniProt Related Accession #

P51888

NCBI Official Full Name

Homo sapiens proline/arginine-rich end leucine-rich repeat protein, mRNA

NCBI Official Synonym Full Names

proline and arginine rich end leucine rich repeat protein

NCBI Official Symbol

PRELP

NCBI Official Synonym Symbols

MST161; SLRR2A; MSTP161

UniProt Protein Name

Prolargin

UniProt Synonym Protein Names

Proline-arginine-rich end leucine-rich repeat protein

Protein Family

Prolargin

UniProt Gene Name

PRELP

UniProt Synonym Gene Names

SLRR2A

UniProt Entry Name

PRELP_HUMAN

NCBI Protein Information

prolargin

NCBI Summary for PRELP

The protein encoded by this gene is a leucine-rich repeat protein present in connective tissue extracellular matrix. This protein functions as a molecule anchoring basement membranes to the underlying connective tissue. This protein has been shown to bind type I collagen to basement membranes and type II collagen to cartilage. It also binds the basement membrane heparan sulfate proteoglycan perlecan. This protein is suggested to be involved in the pathogenesis of Hutchinson-Gilford progeria (HGP), which is reported to lack the binding of collagen in basement membranes and cartilage. Alternatively spliced transcript variants encoding the same protein have been observed. [provided by RefSeq, Jul 2008]

UniProt Comments for PRELP

PRELP: May anchor basement membranes to the underlying connective tissue. Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class II subfamily.

Protein type: Secreted, signal peptide; Motility/polarity/chemotaxis; Secreted

Chromosomal Location of Human Ortholog: 1q32

Cellular Component: extracellular matrix; extracellular region; extracellular space; Golgi lumen; lysosomal lumen

Molecular Function: heparin binding

Biological Process: axonogenesis; keratan sulfate biosynthetic process; keratan sulfate catabolic process; skeletal development

Research Articles on PRELP

1. The unique expression of a 38 kDa PRELP in chronic lymphocytic leukemia (CLL) cells may suggest involvement in the pathobiology of CLL

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with PRELP cdna clone

Products by Pathway	Pathway Diagram
Disease Pathway antibodies	Disease Pathway Diagram
Glycosaminoglycan Metabolism Pathway antibodies	Glycosaminoglycan Metabolism Pathway Diagram
Keratan Sulfate Biosynthesis Pathway antibodies	Keratan Sulfate Biosynthesis Pathway Diagram
Keratan Sulfate Degradation Pathway antibodies	Keratan Sulfate Degradation Pathway Diagram
Keratan Sulfate/keratin Metabolism Pathway antibodies	Keratan Sulfate/keratin Metabolism Pathway Diagram
MPS I - Hurler Syndrome Pathway antibodies	MPS I - Hurler Syndrome Pathway Diagram
MPS II - Hunter Syndrome Pathway antibodies	MPS II - Hunter Syndrome Pathway Diagram
MPS IIIA - Sanfilippo Syndrome A Pathway antibodies	MPS IIIA - Sanfilippo Syndrome A Pathway Diagram
MPS IIIB - Sanfilippo Syndrome B Pathway antibodies	MPS IIIB - Sanfilippo Syndrome B Pathway Diagram
MPS IIIC - Sanfilippo Syndrome C Pathway antibodies	MPS IIIC - Sanfilippo Syndrome C Pathway Diagram

Diseases associated with PRELP cdna clone

Disease Name	Pubmed Publications
Nervous System Diseases Antibodies	>4 publications with PRELP and Nervous System Diseases
Bone Diseases Antibodies	>3 publications with PRELP and Bone Diseases
Arteriosclerosis Antibodies	>2 publications with PRELP and Arteriosclerosis
Immune System Diseases Antibodies	>2 publications with PRELP and Immune System Diseases
Atherosclerosis Antibodies	>2 publications with PRELP and Atherosclerosis
Neoplasms Antibodies	>2 publications with PRELP and Neoplasms
Fibrosis Antibodies	>1 publications with PRELP and Fibrosis
Necrosis Antibodies	>1 publications with PRELP and Necrosis
Inflammation Antibodies	>1 publications with PRELP and Inflammation
Prenatal Exposure Delayed Effects Antibodies	>1 publications with PRELP and Prenatal Exposure Delayed Effects