Human PRICKLE2 cDNA Clone Expression Plasmid – Cat# MBS1277560

PRICKLE2 cDNA Clone – Prickle Homolog 2 (Drosophila) (Human)

Name: PRICKLE2 cDNA Clone; Human; MyBioSource
Brand: MyBioSource
SKU: MBS1277560
Price: 945 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1277560

MBS1277560 is a cDNA clone targeting PRICKLE2. More details

$945 / 0.01 mg Plasmid + 0.2 mL Glycerol-Stock +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

PRICKLE2, cDNA Clone

Full Product Name

PRICKLE2 cDNA Clone

Product Gene Name

PRICKLE2 cdna clone

Sequence

ATGGTGACAG TGATGCCGCT GGAGATGGAG AAGACCATCA GCAAACTCAT GTTTGACTTT CAGAGGAACT CGACCTCAGA TGATGACTCA GGCTGTGCTT TGGAAGAGTA TGCCTGGGTC CCGCCGGGTC TGAAGCCTGA ACAGGTACAC CAGTACTATA GCTGTCTCCC AGAAGAGAAA GTCCCTTATG TCAACAGTCC TGGAGAGAAA CTGCGAATCA AGCAGCTACT ACACCAGCTG CCGCCACATG ACAATGAGGT TCGATATTGC AACTCCCTGG ATGAGGAAGA GAAGAGGGAG CTGAAGCTTT TCAGCAGCCA GAGGAAACGC GAAAACTTGG GCCGCGGGAA TGTCAGGCCT TTCCCAGTCA CCATGACAGG AGCTATTTGT GAACAGTGCG GAGGCCAGAT CAATGGTGGA GACATCGCTG TGTTTGCGTC ACGCGCTGGC CACGGCGTTT GCTGGCACCC GCCGTGCTTC GTATGCACTG TCTGCAATGA GCTCCTGGTG GATCTGATCT ACTTTTACCA AGATGGGAAG ATATACTGTG GCAGGCACCA TGCTGAGTGC CTGAAGCCGC GCTGTGCTGC CTGCGATGAG ATCATCTTTG CAGATGAATG CACAGAAGCT GAGGGGCGAC ACTGGCACAT GAAACACTTT TGCTGCTTCG AGTGTGAGAC AGTGCTGGGC GGCCAGCGCT ACATCATGAA GGAGGGAAGA CCCTACTGTT GCCACTGCTT CGAGTCCTTG TATGCAGAAT ATTGTGACAC CTGTGCCCAA CATATAGGTA TCGACCAAGG TCAAATGACC TATGACGGCC AACACTGGCA TGCCACTGAG ACCTGTTTCT GCTGTGCTCA CTGCAAGAAA TCCCTCCTGG GGCGGCCATT CCTCCCGAAG CAGGGCCAGA TATTCTGCTC ACGGGCCTGC AGTGCTGGGG AAGACCCCAA TGGTTCTGAC TCCTCTGATT CCGCCTTCCA GAACGCCAGG GCCAAGGAGT CCCGGCGCAG TGCCAAAATT GGCAAGAACA AGGGCAAGAC GGAGGAGCCC ATGCTGAACC AGCACAGCCA GCTGCAAGTG AGTTCTAACC GGCTGTCAGC CGACGTAGAC CCCCTGTCAC TGCAGATGGA CATGCTCAGC CTGTCCAGCC AGACACCCAG CCTCAACCGG GACCCCATCT GGAGGAGCCG GGAAGAGCCC TACCATTATG GGAACAAGAT GGAGCAGAAC CAGACCCAGA GCCCTCTGCA GCTCCTCAGC CAGTGCAACA TCAGAACTTC CTACAGTCCA GGAGGGCAAG GGGCTGGGGC CCAGCCCGAA ATGTGGGGCA AGCACTTCAG CAACCCCAAA AGGAGCTCGT CACTGGCCAT GACAGGACAT GCTGGCAGCT TCATCAAGGA ATGCCGAGAA GACTATTACC CGGGGAGGCT GAGATCTCAG GAGAGCTACA GTGATATGTC TAGTCAGAGT TTCAGTGAGA CCCGAGGCAG CATCCAAGTC CCCAAATATG AGGAGGAAGA GGAAGAGGAA GGGGGCTTGT CCACTCAGCA GTGTCGGACC CGTCATCCCA TCAGTTCCCT GAAATACACA GAGGACATGA CGCCCACAGA GCAGACCCCT CGGGGCTCCA TGGAATCCCT GGCCCTGTCT AATGCAACAG GCCTCTCTGC TGATGGTGGT GCCAAGCGCC AGGAGCACCT ATCCCGATTT TCCATGCCTG ACCTCAGCAA AGACTCTGGA ATGAATGTGT CTGAGAAGCT GAGCAACATG GGCACTCTTA ACTCGTCCAT GCAGTTCCGG AGCGCAGAGT CAGTTCGCAG CCTGCTCTCT GCCCAGCAGT ACCAGGAGAT GGAGGGAAAC CTCCACCAGC TCAGCAACCC CATTGGCTAC AGAGACCTGC AGTCCCACGG AAGGATGCAT CAGAGCTTTG ATTTTGATGG AGGGATGGCG GGCAGCAAGC TGCCAGGGCA GGAGGGCGTG AGGATCCAGC CCATGAGTGA ACGCACCCGG AGAAGAGCTA CTTCACGCGA CGACAACCGC CGTTTCCGAC CTCACAGGTC CAGGCGTTCC CGACGCTCTC GCTCCGACAA CGCCCTCCAC CTGGCCAGCG AACGCGAGGC CATCTCCCGG TTAAAAGATA GGCCCCCTCT GAGAGCCAGG GAGGACTATG ACCAATTTAT GCGCCAGCGG AGCTTCCAGG AGAGCATGGG GCATGGGTCC CGGAGGGACC TGTACGGCCA GTGCCCTAGG ACTGTGTCGG ACCTGGCTTT GCAGAATGCC TTTGGGGACC GCTGGGGACC CTACTTCGCC GAGTATGATT GGTGTTCCAC CTGCTCCTCC TCTTCAGAGT CTGACAACGA GGGCTATTTC CTAGGAGAAC CCATCCCCCA GCCAGCGCGC CTGCGATACG TCACAAGCGA TGAGCTGCTG CACAAATACA GCTCCTACGG CCTCCCCAAA TCTTCCACAT TAGGTGGCAG AGGACAGTTG CACAGCAGGA AAAGACAGAA GAGCAAAAAC TGTATCATTT CTTAA

Molecular Weight

95,615 Da

OMIM

607459

Vector

Please Inquire

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of PRICKLE2 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for PRICKLE2. It may not necessarily be applicable to this product.

NCBI GI #

111600369

NCBI GeneID

166336

NCBI Accession #

BC119002

UniProt Secondary Accession #

Q0VF44

UniProt Related Accession #

Q7Z3G6

NCBI Official Full Name

Homo sapiens prickle homolog 2 (Drosophila), mRNA

NCBI Official Synonym Full Names

prickle planar cell polarity protein 2

NCBI Official Symbol

PRICKLE2

NCBI Official Synonym Symbols

EPM5

UniProt Protein Name

Prickle-like protein 2

Protein Family

Prickle-like protein

UniProt Gene Name

PRICKLE2

UniProt Entry Name

PRIC2_HUMAN

NCBI Protein Information

prickle-like protein 2

NCBI Summary for PRICKLE2

This gene encodes a homolog of Drosophila prickle. The exact function of this gene is not known, however, studies in mice suggest that it may be involved in seizure prevention. Mutations in this gene are associated with progressive myoclonic epilepsy type 5. [provided by RefSeq, Dec 2011]

UniProt Comments for PRICKLE2

PRICKLE2: Defects in PRICKLE2 are the cause of progressive myoclonic epilepsy type 5 (EPM5). EPM5 is a neurodegenerative disorder characterized by myoclonic seizures and variable neurologic symptoms including cognitive decline and persistent movement abnormalities. Belongs to the prickle / espinas / testin family.

Protein type: Unknown function

Chromosomal Location of Human Ortholog: 3p14.1

Cellular Component: cytoplasm

Disease: Epilepsy, Progressive Myoclonic 5

Research Articles on PRICKLE2

1. 2 autism-spectrum-disorder patients had distinct, paternally inherited, heterozygous, non-synonymous PRICKLE2 variants (p.E8Q and p.V153I) shared by their affected siblings. These variants had deficits in morphological and electrophysiological assays.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with PRICKLE2 cdna clone

Products by Pathway	Pathway Diagram
Wnt Signaling Pathway antibodies	Wnt Signaling Pathway Diagram
Wnt Signaling Pathway antibodies	Wnt Signaling Pathway Diagram

Diseases associated with PRICKLE2 cdna clone

Disease Name	Pubmed Publications
Neoplasms Antibodies	>4 publications with PRICKLE2 and Neoplasms
Nervous System Diseases Antibodies	>2 publications with PRICKLE2 and Nervous System Diseases
Carcinoma, Squamous Cell Antibodies	>1 publications with PRICKLE2 and Carcinoma, Squamous Cell
Fibrosis Antibodies	>1 publications with PRICKLE2 and Fibrosis
Congenital Abnormalities Antibodies	>1 publications with PRICKLE2 and Congenital Abnormalities
Abnormalities, Multiple Antibodies	>1 publications with PRICKLE2 and Abnormalities, Multiple
Lung Neoplasms Antibodies	>1 publications with PRICKLE2 and Lung Neoplasms
Learning Disorders Antibodies	>1 publications with PRICKLE2 and Learning Disorders
Nervous System Malformations Antibodies	>1 publications with PRICKLE2 and Nervous System Malformations