Human PTPN3 cDNA Clone Expression Plasmid – Cat# MBS1273630

PTPN3 cDNA Clone – Protein Tyrosine Phosphatase, Non-Receptor Type 3 (Human)

Name: PTPN3 cDNA Clone; Human; MyBioSource
Brand: MyBioSource
SKU: MBS1273630
Price: 630 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1273630

MBS1273630 is a cDNA clone targeting PTPN3. More details

$630 / 0.01 mg Plasmid + 0.2 mL Glycerol-Stock +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

PTPN3, cDNA Clone

Full Product Name

PTPN3 cDNA Clone

Product Gene Name

PTPN3 cdna clone

Sequence

atgacctccc ggttacgtgc gttgggtgga agaattaata atatacgcac ctcggagtta cccaaagaga aaactcgatc agaagtcatt tgcagcatcc actttttaga tggcgtggta cagaccttta aagttactaa acaagacact ggccaggttc ttctggatat ggtgcacaac cacctgggtg tgactgaaaa ggaatatttt ggtttacagc atgatgacga ctccgtggac tctcctagat ggctggaagc aagcaaagcc atcaggaagc agttaaaagg aggtttcccc tgtaccctgc attttcgagt aagatttttt atacctgatc ccaacacact gcagcaagaa caaaccaggc acttgtattt cttacaactg aagatggata tttgcgaagg aaggttaacc tgccctctta actcagcagt ggttctagcg tcctatgccg tacaatctca ttttggagac tataattctt ccatacatca tccaggctat ctttccgata gtcactttat acccgatcaa aatgaggact ttttaacaaa agtcgaatct ctgcatgagc agcacagtgg gctaaaacaa tcagaagcag aatcctgcta tatcaacata gcgcggaccc tcgacttcta tggagtagaa ctgcacagtg gtagggatct gcacaattta gacctaatga ttggaattgc ttccgcgggt gttgctgtgt accgaaaata catttgcaca agtttctatc cttgggtgaa cattctcaaa atttctttca aaaggaaaaa gttcttcata catcagcgac agaaacaggc tgaatccagg gaacatattg tggccttcaa catgctgaat taccgatctt gcaaaaactt gtggaaatcc tgtgttgagc accatacgtt ctttcaggca aagaagctac tacctcagga aaagaatgtt ctgtctcagt actggactat gggctctcgg aacaccaaaa agtcggtaaa taaccaatat tgcaaaaagg tgattggcgg gatggtgtgg aacccagcca tgcggagatc cttatcagtg gagcacttag aaaccaagag tctgccttct cgttcccctc ccattactcc caactggcga agtcctcggc tccggcacga aatccgaaag ccacgccact cttctgcaga taaccttgca aatgaaatga cctacatcac ggaaacggaa gatgtatttt acacgtacaa gggctctctg gcccctcaag acagcgattc tgaagtttct cagaaccgaa gcccgcacca agagagttta tccgagaaca atccggcaca aagctacctg acccagaagt catccagttc tgtgtctcca tcttcaaatg ctccaggctc ctgctcacct gacggcgttg atcagcagct cttagatgac ttccacaggg tgaccaaagg gggctccacc gaggacgcca gccagtacta ctgtgacaag aatgataatg gtgacagcta cttagtcttg atccgtatca caccagatga agatggaaaa tttggattta atcttaaggg aggagtggat caaaagatgc ctcttgtggt atcaaggata aacccagagt cacctgcgga cacctgcatt cctaagctga acgaagggga tcaaatcgtg ttaatcaatg gccgggacat ctcagaacac acgcatgacc aagtggtgat gttcatcaaa gccagccggg agtcccactc acgggagctg gccctggtga tcaggaggag agctgtccgc tcatttgctg acttcaagtc tgaagatgaa ctgaaccagc ttttccccga agccattttc cccatgtgtc cggagggtgg ggacactttg gagggatcca tggcacagct aaagaagggc ctcgaaagcg ggacggtgct gatccagttt gagcaactct acagaaaaaa gccaggtttg gccatcacgt ttgcaaagct gcctcaaaat ttggacaaaa accgatataa agatgtgctg ccttatgaca ccacccgggt attattgcag ggaaatgaag attatattaa tgcaagttac gtgaacatgg aaattcctgc tgctaacctt gtgaacaagt acatcgccac tcaggggccc ctgccgcata cctgtgcaca gttttggcag gttgtctggg atcagaagtt gtcactcatt gtcatgttga cgactctcac agaacgaggg cggaccaaat gtcaccagta ctggccagat ccccccgacg tcatgaacca cggcggcttt cacatccagt gtcagtcaga ggactgcacc atcgcctatg tgtcccgaga aatgctggtc acaaacaccc agaccgggga agaacacaca gtgacacatc tccagtacgt cgcatggcct gaccacggtg tgcccgatga ctcctccgac tttctggaat ttgtaaacta tgtgaggtct ctgagagtgg acagcgagcc cgtcctagtt cactgcagtg ctggaatagg tcgaaccggt gtgttggtca ctatggaaac agccatgtgc ctaactgaga ggaacctgcc catttaccca ctggatattg tccgaaaaat gcgagaccag cgcgccatga tggtgcagac atcaagccag tacaagtttg tgtgtgaagc gattcttcgt gtgtatgaag aaggtttagt ccaaatgctg gatcctagtt aa

Molecular Weight

83,723 Da

OMIM

176877

Vector

pENTR223.1 or pUC

Clone Sequence Report

Provided with product shipment

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of PTPN3 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for PTPN3. It may not necessarily be applicable to this product.

NCBI GI #

116496600

NCBI GeneID

5774

NCBI Accession #

BC126117

UniProt Secondary Accession #

A0AUW9; E7EN99; E9PGU7

UniProt Related Accession #

P26045

NCBI Official Full Name

Homo sapiens protein tyrosine phosphatase, non-receptor type 3, mRNA

NCBI Official Synonym Full Names

protein tyrosine phosphatase, non-receptor type 3

NCBI Official Symbol

PTPN3

NCBI Official Synonym Symbols

PTPH1; PTP-H1

UniProt Protein Name

Tyrosine-protein phosphatase non-receptor type 3

UniProt Synonym Protein Names

Protein-tyrosine phosphatase H1; PTP-H1

Protein Family

Tyrosine-protein phosphatase non-receptor

UniProt Gene Name

PTPN3

UniProt Synonym Gene Names

PTPH1; PTP-H1

UniProt Entry Name

PTN3_HUMAN

NCBI Protein Information

tyrosine-protein phosphatase non-receptor type 3

NCBI Summary for PTPN3

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This protein contains a C-terminal PTP domain and an N-terminal domain homologous to the band 4.1 superfamily of cytoskeletal-associated proteins. P97, a cell cycle regulator involved in a variety of membrane related functions, has been shown to be a substrate of this PTP. This PTP was also found to interact with, and be regulated by adaptor protein 14-3-3 beta. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2009]

UniProt Comments for PTPN3

PTPN3: May act at junctions between the membrane and the cytoskeleton. Possesses tyrosine phosphatase activity. Belongs to the protein-tyrosine phosphatase family. Non-receptor class subfamily.

Protein type: Protein phosphatase, tyrosine (non-receptor); Motility/polarity/chemotaxis; EC 3.1.3.48

Chromosomal Location of Human Ortholog: 9q31

Cellular Component: cytoplasm; internal side of plasma membrane

Molecular Function: ATPase binding; phosphotyrosine binding; protein binding; protein tyrosine phosphatase activity; sodium channel regulator activity

Biological Process: negative regulation of membrane protein ectodomain proteolysis; negative regulation of mitotic cell cycle; protein amino acid dephosphorylation

Research Articles on PTPN3

1. Results indicate that protein tyrosine phosphatase non-receptor type 3 (PTPN3) may act as a tumor suppressor in lung cancer through its modulation of epidermal growth factor receptor (EGFR) signaling.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Diseases associated with PTPN3 cdna clone

Disease Name	Pubmed Publications
Carcinoma, Hepatocellular Antibodies	>2 publications with PTPN3 and Carcinoma, Hepatocellular
Breast Neoplasms Antibodies	>2 publications with PTPN3 and Breast Neoplasms
Liver Diseases Antibodies	>2 publications with PTPN3 and Liver Diseases
Lung Diseases Antibodies	>1 publications with PTPN3 and Lung Diseases
Hepatitis Antibodies	>1 publications with PTPN3 and Hepatitis
Necrosis Antibodies	>1 publications with PTPN3 and Necrosis
Inflammation Antibodies	>1 publications with PTPN3 and Inflammation

Organs/Tissues associated with PTPN3 cdna clone

Organ/Tissue Name	Pubmed Publications
Blood Antibodies	>5 publications with PTPN3 and Blood
Liver Antibodies	>3 publications with PTPN3 and Liver
Muscle Antibodies	>3 publications with PTPN3 and Muscle
Lung Antibodies	>2 publications with PTPN3 and Lung
Connective Tissue Antibodies	>1 publications with PTPN3 and Connective Tissue
Nerve Antibodies	>1 publications with PTPN3 and Nerve
Bone Antibodies	>1 publications with PTPN3 and Bone
Intestine Antibodies	>1 publications with PTPN3 and Intestine
Brain Antibodies	>1 publications with PTPN3 and Brain