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PTPN7 cDNA Clone – Protein Tyrosine Phosphatase, Non-Receptor Type 7 (Human)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1271967

MBS1271967 is a cDNA clone targeting PTPN7. More details

$235 / 0.01 mg Plasmid + 0.2 mL Glycerol-Stock +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
PTPN7, cDNA Clone
Full Product Name
PTPN7 cDNA Clone
Product Gene Name
PTPN7 cdna clone
Sequence
atgggagcct ccttctggcc aatcaggcag gccagagaac agcagcggag ggccctgtct ttcaggcaga cctcatggct gagtgagcct cccctgggcc cagcacccca cctcagcatg gtccaagccc atggggggcg ctccagagca cagccgttga ccttgtcttt gggggcagcc atgacccagc ctccgcctga aaaaacgcca gccaagaagc atgtgcgact gcaggagagg cggggctcca atgtggctct gatgctggac gttcggtccc tgggggccgt agaacccatc tgctctgtga acacaccccg ggaggtcacc ctacactttc tgcgcactgc tggacacccc cttacccgct gggcccttca gcgccagcca cccagcccca agcaactgga agaagaattc ttgaagatcc cttcaaactt tgtcagcccc gaagacctgg acatccctgg ccacgcctcc aaggaccgat acaagaccat cttgccaaat ccccagagcc gtgtctgtct aggccgggca cagagccagg aggacggaga ttacatcaat gccaactaca tccgaggcta tgacgggaag gagaaggtct acattgccac ccagggcccc atgcccaaca ctgtgtcgga cttctgggag atggtgtggc aagaggaagt gtccctcatt gtcatgctca ctcagctccg agagggcaag gagaaatgtg tccactactg gcccacagaa gaggaaacct atggaccctt ccagatccgc atccaggaca tgaaagagtg cccagaatac actgtgcggc agctcaccat ccagtaccag gaagagcgcc ggtcagtaaa gcacatcctc ttttcggcct ggccagacca tcagacacca gaatcagctg ggcccctgct gcgcctagtg gcagaggtgg aggagagccc ggagacagcc gcccaccccg ggcctatcgt agtccactgc agtgcaggga ttggccggac gggctgcttc atcgccacgc gaattggctg tcaacagctg aaagcccgag gagaagtgga cattctgggt attgtgtgcc aactgcggct agacagaggg gggatgatcc agacggcaga gcagtaccag ttcctgcacc acactttggc cctgtatgca ggccagctgc ctgaggaacc cagcccctga
Molecular Weight
52,284 Da
OMIM
176889
Vector
pENTR223.1 or pUC
Clone Sequence Report
Provided with product shipment
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of PTPN7 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for PTPN7. It may not necessarily be applicable to this product.

NCBI GI #
12804642
NCBI GeneID
5778
NCBI Accession #
BC001746
UniProt Secondary Accession #
Q53XK4; Q5SXQ0; Q5SXQ1; Q9BV05; B3KXE1
UniProt Related Accession #
P35236
NCBI Official Full Name
Homo sapiens protein tyrosine phosphatase, non-receptor type 7, mRNA
NCBI Official Synonym Full Names
protein tyrosine phosphatase, non-receptor type 7
NCBI Official Symbol
PTPN7
NCBI Official Synonym Symbols
LPTP; HEPTP; PTPNI; BPTP-4; LC-PTP
UniProt Protein Name
Tyrosine-protein phosphatase non-receptor type 7
UniProt Synonym Protein Names
Hematopoietic protein-tyrosine phosphatase; HEPTP; Protein-tyrosine phosphatase LC-PTP
Protein Family
Tyrosine-protein phosphatase non-receptor
UniProt Gene Name
PTPN7
UniProt Synonym Gene Names
HEPTP
UniProt Entry Name
PTN7_HUMAN
NCBI Protein Information
tyrosine-protein phosphatase non-receptor type 7

NCBI Summary for PTPN7

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This gene is preferentially expressed in a variety of hematopoietic cells, and is an early response gene in lymphokine stimulated cells. The non-catalytic N-terminus of this PTP can interact with MAP kinases and suppress the MAP kinase activities. This PTP was shown to be involved in the regulation of T cell antigen receptor (TCR) signaling, which was thought to function through dephosphorylating the molecules related to MAP kinase pathway. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Dec 2010]
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UniProt Comments for PTPN7

HePTP: a non-receptor protein-tyrosine phosphatase. Preferentially expressed in a variety of hematopoietic cells, and is an early response gene in lymphokine stimulated cells. Its noncatalytic N-terminus can interact with MAP kinases and suppress the MAP kinase activities. Shown to be involved in the regulation of T cell antigen receptor (TCR) signaling, which was thought to function through dephosphorylating the molecules related to MAP kinase pathway. Three alternatively spliced transcript variants of this gene, which encode two distinct isoforms, are reported. May play a role in the regulation of lymphocyte development.

Protein type: EC 3.1.3.48; Motility/polarity/chemotaxis; Protein phosphatase, tyrosine (non-receptor)

Chromosomal Location of Human Ortholog: 1q32.1

Cellular Component: cytoplasm; cytosol; internal side of plasma membrane

Molecular Function: protein binding

Biological Process: protein amino acid dephosphorylation
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Research Articles on PTPN7

1. Observational study and genome-wide association study of gene-disease association. (HuGE Navigator)

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with PTPN7 cdna clone

 Products by Pathway  Pathway Diagram
 Downstream Signaling In Naive CD8+ T Cells Pathway antibodies  Downstream Signaling In Naive CD8+ T Cells Pathway Diagram
 MAPK Signaling Pathway antibodies  MAPK Signaling Pathway Diagram
 MAPK Signaling Pathway antibodies  MAPK Signaling Pathway Diagram
 MAPK Signaling Pathway antibodies  MAPK Signaling Pathway Diagram
 Ras Signaling In The CD4+ TCR Pathway antibodies  Ras Signaling In The CD4+ TCR Pathway Diagram

Diseases associated with PTPN7 cdna clone

 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >3 publications with PTPN7 and Neoplasms
 Inflammation Antibodies  >3 publications with PTPN7 and Inflammation
 Lymphoma Antibodies  >1 publications with PTPN7 and Lymphoma
 Hematologic Diseases Antibodies  >1 publications with PTPN7 and Hematologic Diseases
 Necrosis Antibodies  >1 publications with PTPN7 and Necrosis

Organs/Tissues associated with PTPN7 cdna clone

 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >9 publications with PTPN7 and Blood
 Lung Antibodies  >1 publications with PTPN7 and Lung
 Kidney Antibodies  >1 publications with PTPN7 and Kidney
 Brain Antibodies  >1 publications with PTPN7 and Brain
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