Human ROR1 cDNA Clone Expression Plasmid – Cat# MBS1272182

ROR1 cDNA Clone – Receptor Tyrosine Kinase-Like Orphan Receptor 1 (Human)

Name: ROR1 cDNA Clone; Human; MyBioSource
Brand: MyBioSource
SKU: MBS1272182
Price: 480 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1272182

MBS1272182 is a cDNA clone targeting ROR1. More details

$480 / 0.01 mg Plasmid + 0.2 mL Glycerol-Stock +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

ROR1, cDNA Clone

Full Product Name

ROR1 cDNA Clone

Product Gene Name

ROR1 cdna clone

Sequence

atgcaccggc cgcgccgccg cgggacgcgc ccgccgctcc tggcgctgct ggccgcgctg ctgctggccg cacgcggggc tgctgcccaa gaaacagagc tgtcagtcag tgctgaatta gtgcctacct catcatggaa catctcaagt gaactcaaca aagattctta cctgaccctt gatgaaccaa tgaataacat caccacgtct ctgggccaga cagcagaact gcactgcaaa gtctctggga atccacctcc caccatccgc tggttcaaaa atgatgctcc tgtggtccag gagccccgga ggctctcctt tcggtccacc atctatggct ctcggctgcg gattagaaac ctcgacacca cagacacagg ctacttccag tgcgtggcaa caaacggcaa ggaggtggtt tcttccactg gagtcttgtt tgtcaagttt ggcccccctc ccactgcaag tccaggatac tcagatgagt atgaagaaga tggattctgt cagccataca gagggattgc atgtgcaaga tttattggca accgcaccgt ctatatggag tctttgcaca tgcaagggga aatagaaaat cagatcacag ctgccttcac tatgattggc acttccagtc acttatctga taagtgttct cagttcgcca ttccttccct gtgccactat gccttcccgt actgcgatga aacttcatcc gtcccaaagc cccgtgactt gtgtcgcgat gaatgtgaaa tcctggagaa tgtcctgtgt caaacagagt acatttttgc aagatcaaat cccatgattc tgatgaggct gaaactgcca aactgtgaag atctccccca gccagagagc ccagaagctg cgaactgtat ccggattgga attcccatgg cagatcctat aaataaaaat cacaagtgtt ataacagcac aggtgtggac taccggggga ccgtcagtgt gaccaaatca gggcgccagt gccagccatg gaattcccag tatccccaca cacacacttt caccgccctt cgtttcccag agctgaatgg aggccattcc tactgccgca acccagggaa tcaaaaggaa gctccctggt gcttcacctt ggatgaaaac tttaagtctg atctgtgtga catcccagct tgcggtaaat ag

Molecular Weight

43,826 Da

OMIM

602336

Vector

Please Inquire

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of ROR1 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for ROR1. It may not necessarily be applicable to this product.

NCBI GI #

13623530

NCBI GeneID

4919

NCBI Accession #

BC006374

UniProt Secondary Accession #

Q5VVX6; Q66K77; Q92776

UniProt Related Accession #

Q01973

NCBI Official Full Name

Homo sapiens receptor tyrosine kinase-like orphan receptor 1, mRNA

NCBI Official Synonym Full Names

receptor tyrosine kinase like orphan receptor 1

NCBI Official Symbol

ROR1

NCBI Official Synonym Symbols

NTRKR1; dJ537F10.1

UniProt Protein Name

Inactive tyrosine-protein kinase transmembrane receptor ROR1

UniProt Synonym Protein Names

Neurotrophic tyrosine kinase, receptor-related 1

Protein Family

Inactive tyrosine-protein kinase transmembrane receptor

UniProt Gene Name

ROR1

UniProt Synonym Gene Names

NTRKR1

UniProt Entry Name

ROR1_HUMAN

NCBI Protein Information

inactive tyrosine-protein kinase transmembrane receptor ROR1

NCBI Summary for ROR1

This gene encodes a receptor tyrosine kinase-like orphan receptor that modulates neurite growth in the central nervous system. The encoded protein is a glycosylated type I membrane protein that belongs to the ROR subfamily of cell surface receptors. It is a pseudokinase that lacks catalytic activity and may interact with the non-canonical Wnt signalling pathway. This gene is highly expressed during early embryonic development but expressed at very low levels in adult tissues. Increased expression of this gene is associated with B-cell chronic lymphocytic leukaemia. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jun 2012]

UniProt Comments for ROR1

ROR1: Tyrosine-protein kinase receptor whose role is not yet clear. Expressed strongly in human heart, lung and kidney, but weakly in the CNS. Isoform Short is strongly expressed in fetal and adult CNS and in a variety of human cancers, including those originating from CNS or PNS neuroectoderm. Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; EC 2.7.10.1; Protein kinase, TK; Kinase, protein; Protein kinase, tyrosine (receptor); TK group; Ror family

Chromosomal Location of Human Ortholog: 1p31.3

Cellular Component: cytoplasm; integral to plasma membrane; plasma membrane; receptor complex

Molecular Function: protein binding; transmembrane receptor protein tyrosine kinase activity; Wnt-protein binding

Research Articles on ROR1

1. the b-catenin-independent WNT score correlated with reduced overall survival only in the metastasized situation . This is in line with the in vitro results of the alternative WNT receptors ROR1 and ROR2, which foster invasion

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with ROR1 cdna clone

Products by Pathway	Pathway Diagram
Nuclear Receptors Pathway antibodies	Nuclear Receptors Pathway Diagram

Diseases associated with ROR1 cdna clone

Disease Name	Pubmed Publications
Neoplasms Antibodies	>36 publications with ROR1 and Neoplasms
Lymphoma Antibodies	>16 publications with ROR1 and Lymphoma
Carcinoma Antibodies	>6 publications with ROR1 and Carcinoma
Nervous System Diseases Antibodies	>5 publications with ROR1 and Nervous System Diseases
Adenocarcinoma Antibodies	>5 publications with ROR1 and Adenocarcinoma
Lung Neoplasms Antibodies	>4 publications with ROR1 and Lung Neoplasms
Breast Neoplasms Antibodies	>3 publications with ROR1 and Breast Neoplasms
Inflammation Antibodies	>3 publications with ROR1 and Inflammation
Liver Neoplasms Antibodies	>2 publications with ROR1 and Liver Neoplasms
Liver Diseases Antibodies	>2 publications with ROR1 and Liver Diseases

Organs/Tissues associated with ROR1 cdna clone

Organ/Tissue Name	Pubmed Publications
Blood Antibodies	>16 publications with ROR1 and Blood
Brain Antibodies	>16 publications with ROR1 and Brain
Bone Antibodies	>11 publications with ROR1 and Bone
Embryonic Tissue Antibodies	>11 publications with ROR1 and Embryonic Tissue
Lung Antibodies	>9 publications with ROR1 and Lung
Heart Antibodies	>5 publications with ROR1 and Heart
Eye Antibodies	>4 publications with ROR1 and Eye
Thyroid Antibodies	>3 publications with ROR1 and Thyroid
Stomach Antibodies	>3 publications with ROR1 and Stomach
Lymph Node Antibodies	>3 publications with ROR1 and Lymph Node