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RUSC1 cDNA Clone – RUN and SH3 Domain Containing 1 (Human)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1272435

MBS1272435 is a cDNA clone targeting RUSC1. More details

$235 / 0.01 mg Plasmid + 0.2 mL Glycerol-Stock +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
RUSC1, cDNA Clone
Full Product Name
RUSC1 cDNA Clone
Product Gene Name
RUSC1 cdna clone
Sequence
atggcagaag cccagagtgg gactggtcag ctgcaggagc agaagaaagg tcttctgata gccgtcagcg tctccgttga taaaatcatc tcgcatttcg gggccgcccg gaacttggtg cagaaggccc agttgggtga tagccggctg agcccggatg tggggcacct ggtgctgacc accctctgcc cggccctcca cgccctggtg gcggacgggc tgaagccttt ccggaaggac ctcatcaccg ggcagcgcag gagcagcccc tggagcgtgg tggaggcgtc ggtgaagcca ggctccagca cccgctccct tggaaccctg tatagccagg tcagccgtct agccccgctg agcagcagcc gtagccgctt ccatgccttt atcctgggcc tcctcaacac caagcagttg gagctgtggt tttccagtct ccaggaagat gcaggcctgc tctccctcct gtacctgcca acaggatttt tctccctggc ccgcggtggt tgtccctccc tgtccacaga gctgctgctc ctgctgcagc cattgtcggt gctcactttc cacctggacc tgctctttga gcaccaccac cacctgcccc tgggcccacc tcaggcccct gcccctccag gcccacctcc agctctgcag cagactatgc aagccatgct gcactttggg ggccggctgg cccagagcct tcgggggact tccaaggaag ctgcttcaga cccctctgac tctccaaacc ttcccacacc agggagctgg tgggagcagt tgacccaggc ctcccgggtc tatgcctctg ggggcactga gggctttcct ctttcccgat gggcaccggg gcgtcatggg actgcagctg aagaaggtgc acaggagaga cccctgccca cagatgagat ggcaccaggc aggggcctct ggttgggaag actatttgga gtgcctgggg gccccgcaga aaatgagaat ggagccctaa agtccaggag accatctagc tggctgcccc cgacagtgag tgtgttggct cttgtgaagc ggggggcacc tcccgagatg ccttctcctc aggagcttga ggcctcagca cccaggatgg tgcaaaccca tagggcagtg cgggctctct gtgatcacac tgctgcaaga cctgaccagt tgagcttccg gcgtggggaa gtgctgcgtg tcatcaccac agtggatgag gactggctcc gctgtgggcg ggatggcatg gagggtctgg tgcctgtggg gtatacctcc cttgttctgt ag
Molecular Weight
85,216 Da
Vector
pENTR223.1
Clone Sequence Report
Provided with product shipment
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of RUSC1 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for RUSC1. It may not necessarily be applicable to this product.

NCBI GI #
33875915
NCBI GeneID
23623
NCBI Accession #
BC001045
UniProt Secondary Accession #
Q5T9U9; Q5T9V0; Q5T9V1; Q5T9V2; Q9UPY4; Q9Y4T5; B3KWM9
UniProt Related Accession #
Q9BVN2
NCBI Official Full Name
Homo sapiens RUN and SH3 domain containing 1, mRNA
NCBI Official Synonym Full Names
RUN and SH3 domain containing 1
NCBI Official Symbol
RUSC1
NCBI Official Synonym Symbols
NESCA
UniProt Protein Name
RUN and SH3 domain-containing protein 1
UniProt Synonym Protein Names
New molecule containing SH3 at the carboxy-terminus; Nesca
Protein Family
RUN and SH3 domain-containing protein
UniProt Gene Name
RUSC1
UniProt Synonym Gene Names
NESCA; Nesca
UniProt Entry Name
RUSC1_HUMAN
NCBI Protein Information
RUN and SH3 domain-containing protein 1

UniProt Comments for RUSC1

RUSC1: Putative signaling adapter which may play a role in neuronal differentiation. May be involved in regulation of NGF- dependent neurite outgrowth. Proposed to play a role in neuronal vesicular trafficking, specifically involving pre-synaptic membrane proteins. Seems to be involved in signaling pathways that are regulated by the prolonged activation of MAPK. Can regulate the polyubiquitination of IKBKG and thus may be involved in regulation of the NF-kappa-B pathway. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Adaptor/scaffold

Chromosomal Location of Human Ortholog: 1q21-q22

Cellular Component: cytoplasmic vesicle; early endosome; Golgi apparatus; microtubule cytoskeleton

Molecular Function: actin binding; protein binding; SH3/SH2 adaptor activity

Biological Process: protein polyubiquitination
Show more

Research Articles on RUSC1

1. RUN domain of NESCA can bind H-Ras, a downstream signaling molecule of TrkA, with high affinity. Moreover, NESCA RUN can directly interact with TrkA.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with RUSC1 cdna clone

 Products by Pathway  Pathway Diagram
 Trk Receptor Signaling Mediated By The MAPK Pathway antibodies  Trk Receptor Signaling Mediated By The MAPK Pathway Diagram

Diseases associated with RUSC1 cdna clone

 Disease Name  Pubmed Publications
 Inflammation Antibodies  >1 publications with RUSC1 and Inflammation

Organs/Tissues associated with RUSC1 cdna clone

 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >3 publications with RUSC1 and Brain
 Nerve Antibodies  >2 publications with RUSC1 and Nerve
 Placenta Antibodies  >2 publications with RUSC1 and Placenta
 Kidney Antibodies  >1 publications with RUSC1 and Kidney
 Embryonic Tissue Antibodies  >1 publications with RUSC1 and Embryonic Tissue
 Bladder Antibodies  >1 publications with RUSC1 and Bladder
 Prostate Antibodies  >1 publications with RUSC1 and Prostate
 Lung Antibodies  >1 publications with RUSC1 and Lung
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