Human SLC13A3 cDNA Clone Expression Plasmid – Cat# MBS1275286

SLC13A3 cDNA Clone – Solute Carrier Family 13 (Sodium-Dependent Dicarboxylate Transporter), Member 3 (Human)

Name: SLC13A3 cDNA Clone; Human; MyBioSource
Brand: MyBioSource
SKU: MBS1275286
Price: 690 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1275286

MBS1275286 is a cDNA clone targeting SLC13A3. More details

$690 / 0.01 mg Plasmid + 0.2 mL Glycerol-Stock +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

SLC13A3, cDNA Clone

Full Product Name

SLC13A3 cDNA Clone

Product Gene Name

SLC13A3 cdna clone

Sequence

atggcggcgc tggcagcagc ggccaagaag gtgtggagcg cgcggcggct gctggtgctg ctgttcacgc cgctcgcgct gctgccggtg gtcttcgccc tcccgcccaa ggaaggccgc tgcttgtttg tcatcctgct catggcggtg tactggtgca cggaggccct gccgctctca gtgacggcgc tgctgcccat cgtcctgttc cccttcatgg gcatcttgcc ctccaacaag gtctgccccc agtacttcct cgacaccaac ttcctcttcc tcagtgggct gatcatggcc agcgccattg aggagtggaa cctgcaccgg cgaatcgccc tcaagatcct gatgcttgtt ggagtccagc cggccaggct catcctgggg atgatggtga ccacctcgtt cttgtccatg tggctgagca acaccgcctc cactgccatg atgcttccca ttgccaatgc catcctgaaa agtctctttg gccagaagga ggttcgaaag gaccccagcc aggagagtga agagaacaca gctgctgtgc ggagaaacgg cctacacact gtgcccacgg agatgcagtt tctcgccagc acagaagcca aagaccaccc tggggagaca gaggttccac tggatctgcc ggctgactcc aggaaggagg atgaatatcg tcggaacatc tggaagggct tcctcatctc catcccctac tcagccagta ttgggggcac agccacactc acgggcacag cccctaacct catcctgctt ggccagctca agagtttctt tccgcagtgt gacgtggtga atttcggctc ctggttcatt ttcgccttcc ctcttatgct gttgttcctg ttggcaggct ggctctggat ctccttcctg tacgggggac tgagcttcag gggctggagg aagaataaat ctgagataag aaccaatgca gaagataggg ctcgagctgt aattcgggaa gaataccaga acctggggcc catcaagttt gccgaacagg ctgttttcat ccttttctgc atgtttgcca tcctcctctt cacccgggac ccgaagttcg tccctggctg ggccagcctc ttcaatcctg ggtttctttc tgatgctgtc accggcgtgg ctattgtcac catcttgttc ttcttcccgt cccaaaggcc ctctctcaag tggtggtttg acttcaaagc tcccaacaca gagacagagc ccttgctgac ctggaagaag gcccaggaga cagtgccctg gaacatcatc cttctcctgg gagggggctt cgccatggcc aaaggctgtg aggaatcggg gctgtctgta tggattggtg ggcagctgca ccccctggag aatgtgcccc ccgccctggc tgtgctgctc atcactgtgg tcatcgcctt cttcactgag tttgccagca acacggcgac catcatcatc ttcctgccgg tcctggcaga gctggccatc cgcctgagag tgcaccccct gtatctgatg attccgggca cagtcggctg ctcctttgcc ttcatgctcc cggtctcaac gccccccaac tccatcgcct tcgcctctgg acacttgctg gtcaaagaca tggtgcggac aggcctcctg atgaacctga tgggtgtcct gctgctcagt ttggctatga atacctgggc acagaccatc ttccagctgg gcaccttccc ggactgggct gatatgtact cggtcaatgt cacagcattg ccacccacct tggccaatga cacatttcgg accctctga

Molecular Weight

61,757 Da

OMIM

606411

Vector

Please Inquire

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of SLC13A3 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for SLC13A3. It may not necessarily be applicable to this product.

NCBI GI #

23243409

NCBI GeneID

64849

NCBI Accession #

BC035966

UniProt Secondary Accession #

Q5JYC9; Q5JYD0; Q5JYD1; Q5TCQ2; Q8IVB1; Q8N8K4; Q96MM5; Q9BR25; B4DIR8; E1P5U4; F6WI18

UniProt Related Accession #

Q8WWT9

NCBI Official Full Name

Homo sapiens solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3, mRNA

NCBI Official Synonym Full Names

solute carrier family 13 member 3

NCBI Official Symbol

SLC13A3

NCBI Official Synonym Symbols

NADC3; SDCT2

UniProt Protein Name

Solute carrier family 13 member 3

UniProt Synonym Protein Names

Na(+)/dicarboxylate cotransporter 3; NaDC-3; hNaDC3; Sodium-dependent high-affinity dicarboxylate transporter 2

Protein Family

Solute carrier family

UniProt Gene Name

SLC13A3

UniProt Synonym Gene Names

NADC3; SDCT2; NaDC-3; hNaDC3

UniProt Entry Name

S13A3_HUMAN

NCBI Protein Information

solute carrier family 13 member 3

NCBI Summary for SLC13A3

Mammalian sodium-dicarboxylate cotransporters transport succinate and other Krebs cycle intermediates. They fall into 2 categories based on their substrate affinity: low affinity and high affinity. Both the low- and high-affinity transporters play an important role in the handling of citrate by the kidneys. The protein encoded by this gene represents the high-affinity form. Alternatively spliced transcript variants encoding different isoforms have been found for this gene, although the full-length nature of some of them have not been characterized yet. [provided by RefSeq, Jul 2008]

UniProt Comments for SLC13A3

SLC13A3: High-affinity sodium-dicarboxylate cotransporter that accepts a range of substrates with 4-5 carbon atoms. The stoichiometry is probably 3 Na(+) for 1 divalent succinate. Belongs to the SLC13A/DASS transporter (TC 2.A.47) family. NADC subfamily. 4 isoforms of the human protein are produced by alternative splicing.

Protein type: Transporter, SLC family; Membrane protein, multi-pass; Membrane protein, integral; Transporter

Chromosomal Location of Human Ortholog: 20q13.12

Cellular Component: integral to plasma membrane; plasma membrane

Molecular Function: citrate transmembrane transporter activity; high affinity sodium:dicarboxylate symporter activity; sodium:dicarboxylate symporter activity; succinate transmembrane transporter activity

Biological Process: citrate transport

Research Articles on SLC13A3

1. OAT1 and NaDC3 in the basolateral membrane and OAT4 in the luminal membrane of proximal tubule cells are responsible for the avid renal secretion of N-carbamoylglutamate.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with SLC13A3 cdna clone

Products by Pathway	Pathway Diagram
SLC-mediated Transmembrane Transport Pathway antibodies	SLC-mediated Transmembrane Transport Pathway Diagram
Sodium-coupled Sulphate, Di- And Tri-carboxylate Transporters Pathway antibodies	Sodium-coupled Sulphate, Di- And Tri-carboxylate Transporters Pathway Diagram
Transmembrane Transport Of Small Molecules Pathway antibodies	Transmembrane Transport Of Small Molecules Pathway Diagram
Transport Of Glucose And Other Sugars, Bile Salts And Organic Acids, Metal Ions And Amine Compounds Pathway antibodies	Transport Of Glucose And Other Sugars, Bile Salts And Organic Acids, Metal Ions And Amine Compounds Pathway Diagram

Diseases associated with SLC13A3 cdna clone

Disease Name	Pubmed Publications
Kidney Diseases Antibodies	>2 publications with SLC13A3 and Kidney Diseases
Cardiovascular Diseases Antibodies	>1 publications with SLC13A3 and Cardiovascular Diseases
Hypertension Antibodies	>1 publications with SLC13A3 and Hypertension

Organs/Tissues associated with SLC13A3 cdna clone

Organ/Tissue Name	Pubmed Publications
Kidney Antibodies	>6 publications with SLC13A3 and Kidney
Liver Antibodies	>2 publications with SLC13A3 and Liver
Brain Antibodies	>2 publications with SLC13A3 and Brain
Intestine Antibodies	>1 publications with SLC13A3 and Intestine
Eye Antibodies	>1 publications with SLC13A3 and Eye
Placenta Antibodies	>1 publications with SLC13A3 and Placenta