Human SLC22A17 cDNA Clone Expression Plasmid – Cat# MBS1269136

SLC22A17 cDNA Clone – Solute Carrier Family 22, Member 17 (Human)

Name: SLC22A17 cDNA Clone; Human; MyBioSource
Brand: MyBioSource
SKU: MBS1269136
Price: 400 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1269136

MBS1269136 is a cDNA clone targeting SLC22A17. More details

$400 / 0.01 mg Plasmid + 0.2 mL Glycerol-Stock +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

SLC22A17, cDNA Clone

Full Product Name

SLC22A17 cDNA Clone

Product Gene Name

SLC22A17 cdna clone

Sequence

atggcctcgg accccatctt cacgctggcg cccccgctgc attgccacta cggggccttc ccccctaatg cctctggctg ggagcagcct cccaatgcca gcggcgtcag cgtcgccagc gctgccctag cagccagcgc cgccagccgt gtcgccacca gtaccgaccc ctcgtgcagc ggcttcgccc cgccggactt caaccattgc ctcaaggatt gggactataa tggccttcct gtgctcacca ccaacgccat cggccagtgg gatctggtgt gtgacctggg ctggcaggtg atcctggagc agatcctctt catcttgggc tttgcctccg gctacctgtt cctgggttac cccgcagaca gatttggccg tcgcgggatt gtgctgctga ccttggggct ggtgggcccc tgtggagtag gaggggctgc tgcaggctcc tccacaggcg tcatggccct ccgattcctc ttgggctttc tgcttgccgg tgttgacctg ggtgtctacc tgatgcgcct ggagctgtgc gacccaaccc agaggcttcg ggtggccctg gcaggggagt tggtgggggt gggagggcac ttcctgttcc tgggcctggc ccttgtctct aaggattggc gattcctaca gcgaatgatc accgctccct gcatcctctt cctgttttat ggctggcctg gtttgttcct ggagtccgca cggtggctga tagtgaagcg gcagattgag gaggctcagt ctgtgctgag gatcctggct gagcgaaacc ggccccatgg gcagatgctg ggggaggagg cccaggaggc cctgcaggac ctggagaata cctgccctct ccctgcaaca tcctcctttt cctttgcttc cctcctcaac taccgcaaca tctggaaaaa tctgcttatc ctgggcttca ccaacttcat tgcccatgcc attcgccact gctaccagcc tgtgggagga ggagggagcc catcggactt ctacctgtgc tctctgctgg ccagcggcac cgcagccctg gcctgtgtct tcctgggggt caccgtggac cgatttggcc gccggggcat ccttcttctc tccatgaccc ttaccggcat tgcttccctg gtcctgctgg gcctgtggga ttgtgagcat cctatcttcc ccacagtgtg ggctcaacaa gggaacccca acagagatct gaacgaggct gccatcacca ctttctctgt ccttgggctc ttctcctccc aagctgccgc catcctcagc accctccttg ctgctgaggt catccccacc actgtccggg gccgtggcct gggcctgatc atggctctag gggcgcttgg aggactgagc ggcccggccc agcgcctcca catgggccat ggagccttcc tgcagcacgt ggtgctggcg gcctgcgccc tcctctgcat tctcagcatt atgctgctgc cggagaccaa gcgcaagctc ctgcccgagg tgctccggga cggggagctg tgtcgccggc cttccctgct gcggcagcca ccccctaccc gctgtgacca cgtcccgctg cttgccaccc ccaaccctgc cctctga

Molecular Weight

21,712 Da

OMIM

611461

Vector

pENTR223.1 or pUC

Clone Sequence Report

Provided with product shipment

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of SLC22A17 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for SLC22A17. It may not necessarily be applicable to this product.

NCBI GI #

18088250

NCBI GeneID

51310

NCBI Accession #

BC020565

UniProt Secondary Accession #

Q2TAB0; Q5BKY8; Q86U04; Q9H1D3; Q9NQD5; A4UA13; A8MUT0

UniProt Related Accession #

Q8WUG5

NCBI Official Full Name

Homo sapiens solute carrier family 22, member 17, mRNA

NCBI Official Synonym Full Names

solute carrier family 22 member 17

NCBI Official Symbol

SLC22A17

NCBI Official Synonym Symbols

BOCT; BOIT; 24p3R; NGALR; hBOIT; NGALR2; NGALR3

UniProt Protein Name

Solute carrier family 22 member 17

UniProt Synonym Protein Names

24p3 receptor; 24p3R; Brain-type organic cation transporter; Lipocalin-2 receptor; Neutrophil gelatinase-associated lipocalin receptor; NgalR

Protein Family

Solute carrier family

UniProt Gene Name

SLC22A17

UniProt Synonym Gene Names

BOCT; BOIT; 24p3R; NgalR

UniProt Entry Name

S22AH_HUMAN

NCBI Protein Information

solute carrier family 22 member 17

UniProt Comments for SLC22A17

SLC22A17: Cell surface receptor for LCN2 (24p3) that plays a key role in iron homeostasis and transport. Able to bind iron-bound LCN2 (holo-24p3), followed by internalization of holo-24p3 and release of iron, thereby increasing intracellular iron concentration and leading to inhibition of apoptosis. Also binds iron-free LCN2 (apo-24p3), followed by internalization of apo-24p3 and its association with an intracellular siderophore, leading to iron chelation and iron transfer to the extracellular medium, thereby reducing intracellular iron concentration and resulting in apoptosis. Belongs to the major facilitator (TC 2.A.1) superfamily. Organic cation transporter (TC 2.A.1.19) family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Membrane protein, multi-pass; Transporter, SLC family; Transporter

Chromosomal Location of Human Ortholog: 14q11.2

Cellular Component: integral to plasma membrane; plasma membrane

Molecular Function: organic anion transmembrane transporter activity; transmembrane receptor activity; transmembrane transporter activity

Biological Process: cellular iron ion homeostasis; siderophore transport

Research Articles on SLC22A17

1. Biochemical and Structural Characterization of the Interaction between the Siderocalin NGAL/LCN2 (Neutrophil Gelatinase-associated Lipocalin/Lipocalin 2) and the N-terminal Domain of Its Endocytic Receptor SLC22A17.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Diseases associated with SLC22A17 cdna clone

Disease Name	Pubmed Publications
Liver Neoplasms Antibodies	>2 publications with SLC22A17 and Liver Neoplasms
Liver Diseases Antibodies	>2 publications with SLC22A17 and Liver Diseases
Disease Models, Animal Antibodies	>1 publications with SLC22A17 and Disease Models, Animal
Carcinoma, Hepatocellular Antibodies	>1 publications with SLC22A17 and Carcinoma, Hepatocellular

Organs/Tissues associated with SLC22A17 cdna clone

Organ/Tissue Name	Pubmed Publications
Blood Antibodies	>4 publications with SLC22A17 and Blood
Brain Antibodies	>4 publications with SLC22A17 and Brain
Vascular Antibodies	>2 publications with SLC22A17 and Vascular
Uterus Antibodies	>1 publications with SLC22A17 and Uterus
Heart Antibodies	>1 publications with SLC22A17 and Heart
Placenta Antibodies	>1 publications with SLC22A17 and Placenta
Lung Antibodies	>1 publications with SLC22A17 and Lung
Embryonic Tissue Antibodies	>1 publications with SLC22A17 and Embryonic Tissue