Human SLC33A1 cDNA Clone Expression Plasmid – Cat# MBS1274077

SLC33A1 cDNA Clone – Solute Carrier Family 33 (Acetyl-Coa Transporter), Member 1 (Human)

Name: SLC33A1 cDNA Clone; Human; MyBioSource
Brand: MyBioSource
SKU: MBS1274077
Price: 400 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1274077

MBS1274077 is a cDNA clone targeting SLC33A1. More details

$400 / 0.01 mg Plasmid + 0.2 mL Glycerol-Stock +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

SLC33A1, cDNA Clone

Full Product Name

SLC33A1 cDNA Clone

Product Gene Name

SLC33A1 cdna clone

Sequence

atgtcaccca ccatctccca caaggacagc agccggcaac ggcggccagg gaatttcagt cactctctgg atatgaagag cggtcccctg ccgccaggcg gttgggatga cagtcatttg gactcagcgg gccgggaagg ggacagagaa gctcttctgg gggataccgg cactggcgac ttcttaaaag ccccacagag cttccgggcc gaactaagca gcattttgct actactcttt ctttacgtgc ttcagggtat tcccctgggc ttggcgggaa gcatcccact cattttgcaa agcaaaaatg ttagctatac agaccaagct ttcttcagtt ttgtcttttg gcccttcagt ctcaaattac tctgggcccc gttggttgat gcggtctacg ttaagaactt cggtcgtcgc aaatcttggc ttgtcccgac acagtatata ctaggactct tcatgatcta tttatccact caggtggacc gtttgcttgg gaataccgat gacagaacac ccgacgtgat tgctctcact gtggcgttct ttttgtttga attcttggcc gccactcagg acattgccgt cgatggttgg gcgttaacta tgttatccag ggaaaatgtg ggttatgctt ctacttgcaa ttcggtgggc caaacagcgg gttacttttt gggcaatgtt ttgtttttgg cccttgaatc tgccgacttt tgtaacaaat atttgcggtt tcagcctcaa cccagaggaa tcgttactct ttcagatttc ctttttttct ggggaactgt atttttaata acaacaacat tggttgccct tctgaaaaaa gaaaacgaag tatcagtagt aaaagaagaa acacaaggga tcacagatac ttacaagctg ctttttgcaa ttataaaaat gccagcagtt ctgacatttt gccttctgat tctaactgca aagattggtt tttcagcagc agatgctgta acaggactga aattggtaga agagggagta cccaaagaac atttagcctt attggcagtt ccaatggttc ctttgcagat aatactgcct ctgattatca gcaaatacac tgcaggtccc cagccattaa acacatttta caaagccatg ccctacagat tattgcttgg gttagaatat gccctactgg tttggtggac tcctaaagta gaacatcaag ggggattccc tatatattac tatatcgtag tcctgctgag ttatgcttta catcaggtta cagtgtacag catgtatgtt tctataatgg ctttcaatgc aaaggttagt gatccactta ttggaggaac atacatgacc cttttaaata ccgtgtccaa tctgggagga aactggcctt ctacagtagc tctttggctt gtagatcccc tcacagtaaa agagtgtgta ggagcatcaa accagaattg tcgaacacct gatgctgttg agctttgcaa aaaactgggt ggctcatgtg ttacagccct ggatggttat tatgtggagt ccattatttg tgttttcatt ggatttggtt ggtggttctt tcttggtcca aaatttaaaa agttacagga tgaaggatca tcttcgtgga aatgcaaaag gaacaattaa

Molecular Weight

60,909 Da

OMIM

603690

Vector

pENTR223.1 or pUC

Clone Sequence Report

Provided with product shipment

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of SLC33A1 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for SLC33A1. It may not necessarily be applicable to this product.

NCBI GI #

15680145

NCBI GeneID

9197

NCBI Accession #

BC014416

UniProt Secondary Accession #

B2R5Q2; D3DNK4

UniProt Related Accession #

O00400

NCBI Official Full Name

Homo sapiens solute carrier family 33 (acetyl-CoA transporter), member 1, mRNA

NCBI Official Synonym Full Names

solute carrier family 33 member 1

NCBI Official Symbol

SLC33A1

NCBI Official Synonym Symbols

AT1; AT-1; ACATN; SPG42; CCHLND

UniProt Protein Name

Acetyl-coenzyme A transporter 1

UniProt Synonym Protein Names

Solute carrier family 33 member 1

Protein Family

Acetyl-coenzyme A transporter

UniProt Gene Name

SLC33A1

UniProt Synonym Gene Names

ACATN; AT1; AT-1; Acetyl-CoA transporter 1

UniProt Entry Name

ACATN_HUMAN

NCBI Protein Information

acetyl-coenzyme A transporter 1

NCBI Summary for SLC33A1

The protein encoded by this gene is required for the formation of O-acetylated (Ac) gangliosides. The encoded protein is predicted to contain 6 to 10 transmembrane domains, and a leucine zipper motif in transmembrane domain III. Defects in this gene have been reported to cause spastic paraplegia autosomal dominant type 42 (SPG42) in one Chinese family, but not in similar patients of European descent. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2010]

UniProt Comments for SLC33A1

SLC33A1: Probable acetyl-CoA transporter necessary for O- acetylation of gangliosides. Defects in SLC33A1 are the cause of spastic paraplegia autosomal dominant type 42 (SPG42). Spastic paraplegia is a neurodegenerative disorder characterized by a slow, gradual, progressive weakness and spasticity of the lower limbs. Rate of progression and the severity of symptoms are quite variable. Initial symptoms may include difficulty with balance, weakness and stiffness in the legs, muscle spasms, and dragging the toes when walking. In some forms of the disorder, bladder symptoms (such as incontinence) may appear, or the weakness and stiffness may spread to other parts of the body. Defects in SLC33A1 are the cause of congenital cataracts, hearing loss, and neurodegeneration (CCHLND). CCHLND is an autosomal recessive disorder characterized by congenital cataracts, severe psychomotor retardation, and hearing loss associated with decreased serum ceruloplasmin and copper. Brain MRI shows cerebral and cerebellar atrophy and hypomyelination. Belongs to the SLC33A transporter family.

Protein type: Transporter; Membrane protein, multi-pass; Membrane protein, integral; Transporter, SLC family; Glycan Metabolism - glycosphingolipid biosynthesis - ganglio series

Chromosomal Location of Human Ortholog: 3q25.31

Cellular Component: Golgi membrane; integral to plasma membrane; membrane

Molecular Function: acetyl-CoA transporter activity; solute:hydrogen symporter activity

Biological Process: BMP signaling pathway; transmembrane transport; transport

Disease: Congenital Cataracts, Hearing Loss, And Neurodegeneration; Spastic Paraplegia 42, Autosomal Dominant

Research Articles on SLC33A1

1. SLC33A1 can negatively regulate BMP signaling.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with SLC33A1 cdna clone

Products by Pathway	Pathway Diagram
Ganglio Sphingolipid Metabolism Pathway antibodies	Ganglio Sphingolipid Metabolism Pathway Diagram
Glycosphingolipid Biosynthesis - Ganglio Series Pathway antibodies	Glycosphingolipid Biosynthesis - Ganglio Series Pathway Diagram
Glycosphingolipid Biosynthesis - Ganglio Series Pathway antibodies	Glycosphingolipid Biosynthesis - Ganglio Series Pathway Diagram
SLC-mediated Transmembrane Transport Pathway antibodies	SLC-mediated Transmembrane Transport Pathway Diagram
Transmembrane Transport Of Small Molecules Pathway antibodies	Transmembrane Transport Of Small Molecules Pathway Diagram
Transport Of Vitamins, Nucleosides, And Related Molecules Pathway antibodies	Transport Of Vitamins, Nucleosides, And Related Molecules Pathway Diagram

Diseases associated with SLC33A1 cdna clone

Disease Name	Pubmed Publications
Nervous System Diseases Antibodies	>5 publications with SLC33A1 and Nervous System Diseases
Liver Neoplasms Antibodies	>1 publications with SLC33A1 and Liver Neoplasms

Organs/Tissues associated with SLC33A1 cdna clone

Organ/Tissue Name	Pubmed Publications
Brain Antibodies	>4 publications with SLC33A1 and Brain
Embryonic Tissue Antibodies	>2 publications with SLC33A1 and Embryonic Tissue
Liver Antibodies	>1 publications with SLC33A1 and Liver
Skin Antibodies	>1 publications with SLC33A1 and Skin
Blood Antibodies	>1 publications with SLC33A1 and Blood
Bladder Antibodies	>1 publications with SLC33A1 and Bladder
Muscle Antibodies	>1 publications with SLC33A1 and Muscle