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SMEK1 cDNA Clone – SMEK Homolog 1, Suppressor of Mek1 (Dictyostelium) (Human)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1270181

MBS1270181 is a cDNA clone targeting SMEK1. More details

$400 / 0.01 mg Plasmid + 0.2 mL Glycerol-Stock +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
SMEK1, cDNA Clone
Full Product Name
SMEK1 cDNA Clone
Product Gene Name
SMEK1 cdna clone
Sequence
atgaccgaca cccggcggcg ggtgaaggtg tacacgctca acgaggaccg gcagtgggac gaccggggca ccgggcatgt gtcgtctggc tacgtggagc ggctgaaggg catgtccctg cttgtcaggg ctgagagcga cggttctcta cttttagagt cgaaaataaa tcctaacact gcataccaga aacaacagga agatgaaaaa tttctgacag atttgtttgc acaactaaca gatgaagcaa cagatgagga aaaaagacag gaattggtta actttttaaa agaattttgt gcgttttccc aaacgctaca gcctcaaaac agagatgctt ttttcaagac tttgtcaaac atgggcatat taccagcttt agaagtcatc cttggcatgg atgatacaca ggtgcgaagt gctgctactg atatattctc atacttggtt gaatataatc catccatggt acgagagttt gtcatgcagg aggcacaaca gaatgatgat gtaagtaaga agttaacaga gcaaaaaata accagcaagg atattttgct catcaacctc attatagaac atatgatttg tgatacagat cctgaacttg gaggagcagt ccagcttatg ggcctgcttc gaactttagt tgacccagag aacatgctag ccactgccaa taaaacagaa aagactgaat ttctgggttt cttctacaag cactgtatgc atgttctcac tgctccttta ctagcaaata caacagaaga caaacctagt aaagatgatt ttcagactgc ccaactattg gcacttgtat tggaattgtt aacattttgt gtggagcacc atacctacca cataaagaac tacattatta ataaggatat cctccggaga gtgctagttc ttatggcctc gaagcatgct ttcttggcat tatgtgccct tcgttttaaa agaaagatta ttggattaaa agatgagttt tacaaccgct acataatgaa aagttttttg tttgaaccag tagtgaaagc atttctcaac aatggatccc gctacaatct gatgaactct gccataatag agatgtttga atttattaga gtggaagata taaaatcatt aactgctcat gtaattgaaa attactggaa agcactggaa gatgtagatt atgtacagac atttaaagga ttaaaactga gatttgaaca acaaagagaa aggcaagata atcccaaact tgacagtatg cgttccattt tgaggaatca cagatatcga agagatgcca gaacactaga agatgaagaa gagatgtggt ttaacacaga tgaagatgac atggaagatg gagaagctgt agtgtctcca tctgacaaaa ctaaaaatga tgatgatatt atggatccaa taagtaaatt catggaaagg aagaaattaa aagaaagtga ggaaaaggaa gtgcttctga aaacaaacct ttctggacgg cagagcccaa gtttcaagct ttccctgtcc agtggaacga agactaacct caccagccag tcatctacaa caaatctgcc tggttctccg ggatcacctg gatccccagg atctccaggc tctcctggat ccgtacctaa aaatacatct cagacggcag ctattactac aaagggaggc ctcgtgggtc tggtagatta tcctgatgat gatgaagatg atgatgagga tgaagataag gaagatacgt taccattgtc aaagaaagca aaatttgatt cataa
Molecular Weight
62,020 Da
OMIM
610351
Vector
pENTR223.1 or pUC
Clone Sequence Report
Provided with product shipment
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of SMEK1 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for SMEK1. It may not necessarily be applicable to this product.

NCBI GI #
25058564
NCBI GeneID
55671
NCBI Accession #
BC038932
UniProt Secondary Accession #
Q69YK6; Q86U23; Q86YI7; Q8IVG1; Q9H3F1; Q9H7U8; Q9NV01; Q9NWP1
UniProt Related Accession #
Q6IN85
NCBI Official Full Name
Homo sapiens SMEK homolog 1, suppressor of mek1 (Dictyostelium), mRNA
NCBI Official Synonym Full Names
protein phosphatase 4 regulatory subunit 3A
NCBI Official Symbol
PPP4R3A
NCBI Official Synonym Symbols
smk1; FLFL1; PP4R3; SMEK1; smk-1; PP4R3A; MSTP033; KIAA2010
UniProt Protein Name
Serine/threonine-protein phosphatase 4 regulatory subunit 3A
UniProt Synonym Protein Names
SMEK homolog 1
UniProt Gene Name
PPP4R3A
UniProt Entry Name
P4R3A_HUMAN
NCBI Protein Information
serine/threonine-protein phosphatase 4 regulatory subunit 3A

UniProt Comments for SMEK1

SMEK1: a conserved single-pass membrane protein. In Dictyostelium, the SMEK homolog regulates myosin II assembly and cytokinesis during vegetative growth. Loss of SMEK suppresses defects in cell polarity, chemotaxis, and gene expression in MEK1 null cells. Six alternatively-spliced isoforms have been described.

Protein type: Membrane protein, integral; Protein phosphatase, regulatory subunit; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 14q32.12
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Research Articles on SMEK1

1. Loss of sMEK1 is associated with Ovarian Neoplasms.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with SMEK1 cdna clone

 Products by Pathway  Pathway Diagram
 Integrated Breast Cancer Pathway antibodies  Integrated Breast Cancer Pathway Diagram

Diseases associated with SMEK1 cdna clone

 Disease Name  Pubmed Publications
 Carcinoma Antibodies  >1 publications with SMEK1 and Carcinoma
 Ovarian Diseases Antibodies  >1 publications with SMEK1 and Ovarian Diseases
 Uterine Cervical Neoplasms Antibodies  >1 publications with SMEK1 and Uterine Cervical Neoplasms

Organs/Tissues associated with SMEK1 cdna clone

 Organ/Tissue Name  Pubmed Publications
 Vascular Antibodies  >1 publications with SMEK1 and Vascular
 Liver Antibodies  >1 publications with SMEK1 and Liver
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