Human SRGAP1 cDNA Clone Expression Plasmid – Cat# MBS1273706

SRGAP1 cDNA Clone – SLIT-ROBO Rho Gtpase Activating Protein 1 (Human)

Name: SRGAP1 cDNA Clone; Human; MyBioSource
Brand: MyBioSource
SKU: MBS1273706
Price: 235 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1273706

MBS1273706 is a cDNA clone targeting SRGAP1. More details

$235 / 0.01 mg Plasmid + 0.2 mL Glycerol-Stock +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

SRGAP1, cDNA Clone

Full Product Name

SRGAP1 cDNA Clone

Product Gene Name

SRGAP1 cdna clone

Sequence

atgcgagttc agcttctcca ggatctgcaa gatttcttcc gaaaaaaagc tgaaattgag acggaatatt cccggaatct agagaagtta gcagaaaggt tcatggcaaa aacaagaagc actaaggatc atcaacaata caagaaagac cagaacctgt tgtctccagt gaactgctgg tatttgctcc tgaaccaagt aaggagagaa agcaaagacc atgcaacctt gagtgacatc tatctgaaca atgtgattat gcggttcatg cagataagtg aggattctac caggatgttt aaaaagagca aagagattgc attccaactt catgaggatt taatgaaggt tcttaatgag ctttatacgg tgatgaaaac ataccatatg tatcatgcag agagcatcag tgcagagagc aagctgaaag aggccgaaaa acaagaggaa aagcaaattg ggagatctgg tgatccagtc ttccatattc gactagagga gagacatcaa cggcgaagct ctgtaaagaa aattgaaaaa atgaaagaaa aaagacaagc aaaatattca gaaaataagc taaaatcaat taaggcacgg aacgaatatc tcctaacact tgaagccacc aatgcctcag ttttcaagta ctatattcat gatctttctg atttaattga ttgctgtgat cttggctacc atgcaagtct gaacagagcc ctaagaacat atctgtctgc ggagtacaac cttgaaacct ccagacatga gggcttagac attattgaga atgcagttga taatttagag cccaggagcg ataagcagag attcatggag atgtaccctg ctgcgttctg tccaccaatg aagtttgagt ttcagtctca catgggtgat gaggtgtgcc aggtcagtgc ccagcagcca gtccaggcag agctcatgct caggtaccaa cagttgcagt cccgccttgc cacgctcaaa atcgagaatg aagaggttaa gaaaacgact gaagccacct tgcagacgat acaagatatg gtcaccatcg aggactatga tgtttctgaa tgcttccagc acagtcgttc cacagaatct gtgaagtcca ctgtctctga aacctacctg agtaaaccca gcatcgccaa gagaagagcc aaccagcagg aaactgaaca gttctacttc atgaaactca gagaatattt ggaaggcagt aatctcatca caaaacttca agccaaacat gacttgctgc agaggaccct gggagaaggt gagttatcca aaatgtatgg gaagatgacc tggatgatac atcgtatcat gtatatattc cagaaagagt atgaattgta tatttgtgct ttaagaagca gaggacactc tgtgtttaga tttggttttg tttgtatatg tcatgattaa

Molecular Weight

121,594 Da

OMIM

188470

Vector

pENTR223.1 or pUC

Clone Sequence Report

Provided with product shipment

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of SRGAP1 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for SRGAP1. It may not necessarily be applicable to this product.

NCBI GI #

20988664

NCBI GeneID

57522

NCBI Accession #

BC029919

UniProt Secondary Accession #

Q9H8A3; Q9P2P2

UniProt Related Accession #

Q7Z6B7

NCBI Official Full Name

Homo sapiens SLIT-ROBO Rho GTPase activating protein 1, mRNA

NCBI Official Synonym Full Names

SLIT-ROBO Rho GTPase activating protein 1

NCBI Official Symbol

SRGAP1

NCBI Official Synonym Symbols

NMTC2; ARHGAP13

UniProt Protein Name

SLIT-ROBO Rho GTPase-activating protein 1

UniProt Synonym Protein Names

Rho GTPase-activating protein 13

Protein Family

SLIT-ROBO Rho GTPase-activating protein

UniProt Gene Name

SRGAP1

UniProt Synonym Gene Names

ARHGAP13; KIAA1304; srGAP1

UniProt Entry Name

SRGP1_HUMAN

NCBI Protein Information

SLIT-ROBO Rho GTPase-activating protein 1

UniProt Comments for SRGAP1

ARHGAP13: GTPase-activating protein for RhoA and Cdc42 small GTPases. Together with CDC42 seems to be involved in the pathway mediating the repulsive signaling of Robo and Slit proteins in neuronal migration. SLIT2, probably through interaction with ROBO1, increases the interaction of SRGAP1 with ROBO1 and inactivates CDC42. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: GAPs; GAPs, Rac/Rho

Chromosomal Location of Human Ortholog: 12q14.2

Cellular Component: cytoplasm; cytosol

Molecular Function: GTPase activator activity; protein binding; Rac GTPase binding

Biological Process: negative regulation of cell migration; regulation of small GTPase mediated signal transduction

Disease: Thyroid Carcinoma, Follicular

Research Articles on SRGAP1

1. we identified a consistently replicated loci at 12q14.2 (rs11175194 in SRGAP1, P(meta) = 1.14 x 10(-7))

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with SRGAP1 cdna clone

Products by Pathway	Pathway Diagram
Axon Guidance Pathway antibodies	Axon Guidance Pathway Diagram
Axon Guidance Pathway antibodies	Axon Guidance Pathway Diagram
Axon Guidance Pathway antibodies	Axon Guidance Pathway Diagram
Axon Guidance Pathway antibodies	Axon Guidance Pathway Diagram
Developmental Biology Pathway antibodies	Developmental Biology Pathway Diagram
Developmental Biology Pathway antibodies	Developmental Biology Pathway Diagram
Inactivation Of Cdc42 And Rac Pathway antibodies	Inactivation Of Cdc42 And Rac Pathway Diagram
Inactivation Of Cdc42 And Rac Pathway antibodies	Inactivation Of Cdc42 And Rac Pathway Diagram
Regulation Of RhoA Activity Pathway antibodies	Regulation Of RhoA Activity Pathway Diagram
Rho GTPase Cycle Pathway antibodies	Rho GTPase Cycle Pathway Diagram

Diseases associated with SRGAP1 cdna clone

Disease Name	Pubmed Publications
Lung Diseases Antibodies	>2 publications with SRGAP1 and Lung Diseases
Nervous System Diseases Antibodies	>1 publications with SRGAP1 and Nervous System Diseases
Pneumonia Antibodies	>1 publications with SRGAP1 and Pneumonia
Lung Neoplasms Antibodies	>1 publications with SRGAP1 and Lung Neoplasms
Neoplasms Antibodies	>1 publications with SRGAP1 and Neoplasms
Inflammation Antibodies	>1 publications with SRGAP1 and Inflammation

Organs/Tissues associated with SRGAP1 cdna clone

Organ/Tissue Name	Pubmed Publications
Embryonic Tissue Antibodies	>3 publications with SRGAP1 and Embryonic Tissue