• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

STAT4 cDNA Clone – Signal Transducer and Activator of Transcription 4 (Human)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1278133

MBS1278133 is a cDNA clone targeting STAT4. More details

$235 / 0.01 mg Plasmid + 0.2 mL Glycerol-Stock +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
STAT4, cDNA Clone
Full Product Name
STAT4 cDNA Clone
Product Gene Name
STAT4 cdna clone
Sequence
atgtctcagt ggaatcaagt ccaacagtta gaaatcaagt ttttggagca ggtggatcaa ttctatgatg acaactttcc catggaaatt cggcatctgt tggcccaatg gattgaaaat caagactggg aggcagcttc taacaatgaa accatggcaa cgattcttct tcaaaacttg ttaatacaac tggatgaaca gttaggtcgt gtttccaaag agaaaaacct actcttgata cacaatctaa aaagaattag gaaggtcctt cagggaaaat ttcatggaaa tccaatgcat gtagctgtgg ttatttcaaa ctgtttaagg gaagagagga gaatattggc tgcagccaac atgcctgtcc aggggcctct agagaaatcc ttacaaagtt cttcagtttc agaaagacag aggaatgtgg agcacaaagt ggctgccatt aaaaacagtg tgcagatgac agaacaagat accaaatact tagaagatct gcaagacgaa tttgactaca ggtataaaac aattcagaca atggatcaga gtgacaagaa tagtgccatg gtgaatcagg aagttttgac actgcaggaa atgcttaaca gcctcgattt caagagaaag gaggctctca gtaaaatgac ccaaatcatc catgagacag acctgttaat gaacaccatg ctcatagaag agctgcaaga ctggaagcgg cggcagcaaa tcgcctgcat cgggggtcca ctccacaatg ggctcgacca gcttcagaac tgctttacac tattggcaga aagtcttttc caactgagaa ggcaattgga gaaactagag gagcaatcta ccaaaatgac atatgaaggt gatcccattc caatgcaaag aactcacatg ctagaaagag tcaccttctt gatctacaac cttttcaaga actcatttgt ggttgagcga cagccatgta tgccaaccca ccctcagagg ccgttggtac ttaaaaccct aattcagttc actgtaaaac taaggctact aataaaattg ccagaactaa actatcaggt aaaggttaag gcatcaattg acaagaatgt ttcaactcta agcaaccgaa gatttgtact ttgtggaact aatgtcaaag ccatgtctat tgaagaatct tccaatggga gtctctcagt agaatttcga catttgcaac caaaggaaat gaagtccagt gctggaggta aaggaaatga gggctgtcac atggtgactg aagaacttca ttccataacg tttgaaacac agatctgcct ctatggcctg accatagatt tggagaccag ctcattgcct gtggtgatga tttccaatgt cagtcagtta cctaatgctt gggcatccat catttggtac aacgtgtcaa ccaacgattc ccagaacttg gttttcttta ataatcctcc acctgccaca ttgagtcaac tactggaggt gatgagctgg cagttttcat cgtacgttgg tcgtggtctt aactcagatc aactccatat gctggcagag aagcttacag tccaatctag ctacagtgat ggtcacctca cctgggccaa gttctgcaag gaacatttac ctggtaaatc atttaccttt tggacatggc ttgaagcaat attggatcta attaagaaac acattcttcc cctttggatt gatgggtatg tcatgggctt tgttagcaaa gagaaggaac ggctgttgct aaaggataaa atgcctggca cctttttatt aagattcagt gaaagccatc tcggaggaat aactttcacc tgggtggacc attctgaaag tggggaagtg agattccact ctgtagaacc ctacaataaa ggccggttgt ctgctctgcc attcgctgac atcctgcgag actacaaagt tattatggct gaaaacattc ctgaaaaccc tctgaagtac ctatatcctg acattcccaa agacaaagcc ttcggtaaac actacagctc tcagccttgc gaagtttcaa gaccaacaga aaggggtgac aaaggttatg ttccttctgt ttttatcccc atctcaacaa tccgaagtga ttcaacagag ccacattctc catcagacct tcttcccatg tctccaagtg tgtatgcggt gttgagagaa aacctgagtc ccacaacaat tgaaactgca atgaagtctc cttattctgc tgaatga
Molecular Weight
85,941 Da
OMIM
180300
Vector
pENTR223.1
Clone Sequence Report
Provided with product shipment
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of STAT4 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for STAT4. It may not necessarily be applicable to this product.

NCBI GI #
21411473
NCBI GeneID
6775
NCBI Accession #
BC031212
UniProt Secondary Accession #
Q96NZ6
UniProt Related Accession #
Q14765
NCBI Official Full Name
Homo sapiens signal transducer and activator of transcription 4, mRNA
NCBI Official Synonym Full Names
signal transducer and activator of transcription 4
NCBI Official Symbol
STAT4
NCBI Official Synonym Symbols
SLEB11
UniProt Protein Name
Signal transducer and activator of transcription 4
Protein Family
Signal transducer and activator of transcription
UniProt Gene Name
STAT4
UniProt Entry Name
STAT4_HUMAN
NCBI Protein Information
signal transducer and activator of transcription 4

NCBI Summary for STAT4

The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is essential for mediating responses to IL12 in lymphocytes, and regulating the differentiation of T helper cells. Mutations in this gene may be associated with systemic lupus erythematosus and rheumatoid arthritis. Alternate splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Aug 2011]
Show more

UniProt Comments for STAT4

STAT4: transcription factor of the STAT family. Phosphorylated and activated by receptor-associated kinases downstream of many cytokines and growth-factor receptors. Essential for mediating responses to IL12 in lymphocytes, and regulating the differentiation of T helper cells.

Protein type: DNA-binding; Transcription factor

Chromosomal Location of Human Ortholog: 2q32.2-q32.3

Cellular Component: nucleoplasm

Molecular Function: protein binding

Biological Process: JAK-STAT cascade

Disease: Systemic Lupus Erythematosus, Susceptibility To, 11
Show more

Research Articles on STAT4

1. There is a significant association between STAT4 rs7574865 polymorphism and IBD susceptibility in overall population.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with STAT4 cdna clone

 Products by Pathway  Pathway Diagram
 Downstream Signaling In Naive CD8+ T Cells Pathway antibodies  Downstream Signaling In Naive CD8+ T Cells Pathway Diagram
 Hepatitis B Pathway antibodies  Hepatitis B Pathway Diagram
 IL12 Signaling Mediated By STAT4 Pathway antibodies  IL12 Signaling Mediated By STAT4 Pathway Diagram
 IL12-mediated Signaling Events Pathway antibodies  IL12-mediated Signaling Events Pathway Diagram
 IL23-mediated Signaling Events Pathway antibodies  IL23-mediated Signaling Events Pathway Diagram
 IL27-mediated Signaling Events Pathway antibodies  IL27-mediated Signaling Events Pathway Diagram
 Jak-STAT Signaling Pathway antibodies  Jak-STAT Signaling Pathway Diagram
 Jak-STAT Signaling Pathway antibodies  Jak-STAT Signaling Pathway Diagram
 TSLP Signaling Pathway antibodies  TSLP Signaling Pathway Diagram

Diseases associated with STAT4 cdna clone

 Disease Name  Pubmed Publications
 Inflammation Antibodies  >136 publications with STAT4 and Inflammation
 Arthritis, Rheumatoid Antibodies  >105 publications with STAT4 and Arthritis, Rheumatoid
 Lupus Erythematosus, Systemic Antibodies  >85 publications with STAT4 and Lupus Erythematosus, Systemic
 Necrosis Antibodies  >71 publications with STAT4 and Necrosis
 Neoplasms Antibodies  >54 publications with STAT4 and Neoplasms
 Cardiovascular Diseases Antibodies  >35 publications with STAT4 and Cardiovascular Diseases
 Liver Diseases Antibodies  >26 publications with STAT4 and Liver Diseases
 Scleroderma, Systemic Antibodies  >18 publications with STAT4 and Scleroderma, Systemic
 Kidney Diseases Antibodies  >17 publications with STAT4 and Kidney Diseases
 Drug Toxicity Antibodies  >16 publications with STAT4 and Drug Toxicity

Organs/Tissues associated with STAT4 cdna clone

 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >609 publications with STAT4 and Blood
 Spleen Antibodies  >73 publications with STAT4 and Spleen
 Skin Antibodies  >52 publications with STAT4 and Skin
 Lung Antibodies  >45 publications with STAT4 and Lung
 Lymph Node Antibodies  >30 publications with STAT4 and Lymph Node
 Heart Antibodies  >28 publications with STAT4 and Heart
 Intestine Antibodies  >27 publications with STAT4 and Intestine
 Bone Marrow Antibodies  >15 publications with STAT4 and Bone Marrow
 Kidney Antibodies  >15 publications with STAT4 and Kidney
 Brain Antibodies  >15 publications with STAT4 and Brain
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000