Human SULT2B1 cDNA Clone Expression Plasmid – Cat# MBS1271013

SULT2B1 cDNA Clone – Sulfotransferase Family, Cytosolic, 2b, Member 1 (Human)

Name: SULT2B1 cDNA Clone; Human; MyBioSource
Brand: MyBioSource
SKU: MBS1271013
Price: 235 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1271013

MBS1271013 is a cDNA clone targeting SULT2B1. More details

$235 / 0.01 mg Plasmid + 0.2 mL Glycerol-Stock +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

SULT2B1, cDNA Clone

Full Product Name

SULT2B1 cDNA Clone

Product Gene Name

SULT2B1 cdna clone

Sequence

atggacgggc ccgccgagcc ccagatcccg ggcttgtggg acacctatga agatgacatc tcggaaatca gccagaagtt gccaggtgaa tacttccggt acaagggcgt ccccttcccc gtcggcctgt actcgctcga gagcatcagc ttggcggaga acacccaaga tgtgcgggac gacgacatct ttatcatcac ctaccccaag tcaggcacga cctggatgat cgagatcatc tgcttaatcc tgaaggaagg ggatccatcc tggatccgct ccgtgcccat ctgggagcgg gcaccctggt gtgagaccat tgtgggtgcc ttcagcctcc cggaccagta cagcccccgc ctcatgagct cccatcttcc catccagatc ttcaccaagg ccttcttcag ctccaaggcc aaggtgatct acatgggccg caacccccgg gacgttgtgg tctccctcta tcattactcc aagatcgccg ggcagttaaa ggacccgggc acacccgacc agttcctgag ggacttcctc aaaggcgaag tgcagtttgg ctcctggttc gaccacatta agggctggct tcggatgaag ggcaaagaca acttcctatt tatcacctac gaggagctgc agcaggactt acagggctcc gtggagcgca tctgtgggtt cctgggccgt ccgctgggca aggaggcact gggctccgtc gtggcacact caaccttcag cgccatgaag gccaacacca tgtccaacta cacgctgctg cctcccagcc tgctggacca ccgtcgcggg gccttcctcc ggaaaggggt ctgtggcgac tggaagaacc acttcacggt ggcccagagc gaagccttcg atcgtgccta ccgcaagcag atgcggggga tgccgacctt cccctgggat gaagacccgg aggaggacgg cagcccagat cctgagccca gccctgagcc tgagcccaag cccagccttg agcccaacac cagcctggag cgtgagccca gacccaactc cagccccagc cccagccccg gccaggcctc tgagaccccg cacccacgac cctcataa

Molecular Weight

39,599 Da

OMIM

604125

Vector

pENTR223.1 or pUC

Clone Sequence Report

Provided with product shipment

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of SULT2B1 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for SULT2B1. It may not necessarily be applicable to this product.

NCBI GI #

21961208

NCBI GeneID

6820

NCBI Accession #

BC034694

UniProt Secondary Accession #

O00205; O75814

UniProt Related Accession #

O00204

NCBI Official Full Name

Homo sapiens sulfotransferase family, cytosolic, 2B, member 1, mRNA

NCBI Official Synonym Full Names

sulfotransferase family 2B member 1

NCBI Official Symbol

SULT2B1

NCBI Official Synonym Symbols

HSST2

UniProt Protein Name

Sulfotransferase family cytosolic 2B member 1

UniProt Synonym Protein Names

Alcohol sulfotransferase; Hydroxysteroid sulfotransferase 2

Protein Family

Sulfotransferase family cytosolic

UniProt Gene Name

SULT2B1

UniProt Synonym Gene Names

HSST2; ST2B1; Sulfotransferase 2B1

UniProt Entry Name

ST2B1_HUMAN

NCBI Protein Information

sulfotransferase family cytosolic 2B member 1

NCBI Summary for SULT2B1

Sulfotransferase enzymes catalyze the sulfate conjugation of many hormones, neurotransmitters, drugs, and xenobiotic compounds. These cytosolic enzymes are different in their tissue distributions and substrate specificities. The gene structure (number and length of exons) is similar among family members. This gene sulfates dehydroepiandrosterone but not 4-nitrophenol, a typical substrate for the phenol and estrogen sulfotransferase subfamilies. Two alternatively spliced variants that encode different isoforms have been described. [provided by RefSeq, Jul 2008]

UniProt Comments for SULT2B1

SULT2B1: Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of many hormones, neurotransmitters, drugs and xenobiotic compounds. Sulfonation increases the water solubility of most compounds, and therefore their renal excretion, but it can also result in bioactivation to form active metabolites. Sulfates hydroxysteroids like DHEA. Isoform 1 preferentially sulfonates cholesterol, and isoform 2 avidly sulfonates pregnenolone but not cholesterol. Belongs to the sulfotransferase 1 family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Energy Metabolism - sulfur; EC 2.8.2.2; Transferase; Lipid Metabolism - androgen and estrogen

Chromosomal Location of Human Ortholog: 19q13.3

Cellular Component: cytoplasm; cytosol; intracellular membrane-bound organelle

Molecular Function: alcohol sulfotransferase activity; protein binding; steroid sulfotransferase activity

Biological Process: 3'-phosphoadenosine 5'-phosphosulfate metabolic process; steroid metabolic process

Research Articles on SULT2B1

1. Since 1'-hydroxyestragole exposure readily produced DNA injury in B-13/H cells, these data suggest that cholangiocarcinomas generated in rats fed estragole may be dependent, in part, on SULT2B1 activation of the 1'-hydroxyestragole metabolite.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with SULT2B1 cdna clone

Products by Pathway	Pathway Diagram
Biological Oxidations Pathway antibodies	Biological Oxidations Pathway Diagram
Cytosolic Sulfonation Of Small Molecules Pathway antibodies	Cytosolic Sulfonation Of Small Molecules Pathway Diagram
Metabolism Pathway antibodies	Metabolism Pathway Diagram
Phase II Conjugation Pathway antibodies	Phase II Conjugation Pathway Diagram
Steroid Hormone Biosynthesis Pathway antibodies	Steroid Hormone Biosynthesis Pathway Diagram
Steroid Hormone Biosynthesis Pathway antibodies	Steroid Hormone Biosynthesis Pathway Diagram
Sulfation Biotransformation Reaction Pathway antibodies	Sulfation Biotransformation Reaction Pathway Diagram
Sulfur Metabolism Pathway antibodies	Sulfur Metabolism Pathway Diagram
Sulfur Metabolism Pathway antibodies	Sulfur Metabolism Pathway Diagram
Vitamin A And Carotenoid Metabolism Pathway antibodies	Vitamin A And Carotenoid Metabolism Pathway Diagram

Diseases associated with SULT2B1 cdna clone

Disease Name	Pubmed Publications
Neoplasms Antibodies	>8 publications with SULT2B1 and Neoplasms
Carcinoma Antibodies	>7 publications with SULT2B1 and Carcinoma
Adenocarcinoma Antibodies	>5 publications with SULT2B1 and Adenocarcinoma
Breast Neoplasms Antibodies	>5 publications with SULT2B1 and Breast Neoplasms
Hyperplasia Antibodies	>2 publications with SULT2B1 and Hyperplasia
Atherosclerosis Antibodies	>1 publications with SULT2B1 and Atherosclerosis
Carcinoma, Hepatocellular Antibodies	>1 publications with SULT2B1 and Carcinoma, Hepatocellular
Nervous System Diseases Antibodies	>1 publications with SULT2B1 and Nervous System Diseases
Inflammation Antibodies	>1 publications with SULT2B1 and Inflammation
Fatty Liver Antibodies	>1 publications with SULT2B1 and Fatty Liver

Organs/Tissues associated with SULT2B1 cdna clone

Organ/Tissue Name	Pubmed Publications
Skin Antibodies	>7 publications with SULT2B1 and Skin
Prostate Antibodies	>6 publications with SULT2B1 and Prostate
Intestine Antibodies	>5 publications with SULT2B1 and Intestine
Brain Antibodies	>5 publications with SULT2B1 and Brain
Placenta Antibodies	>5 publications with SULT2B1 and Placenta
Lung Antibodies	>4 publications with SULT2B1 and Lung
Testis Antibodies	>4 publications with SULT2B1 and Testis
Kidney Antibodies	>2 publications with SULT2B1 and Kidney
Connective Tissue Antibodies	>1 publications with SULT2B1 and Connective Tissue