TAGLN cDNA Clone Expression Plasmid – Cat# MBS200649

TAGLN cDNA Clone – Transgelin

Name: TAGLN cDNA Clone; Transgelin; MyBioSource
Brand: MyBioSource
SKU: MBS200649
Price: 245 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS200649

TAGLN encoded by this gene is a transformation and shape-change sensitive actin cross-linking/gelling protein found in fibroblasts and smooth muscle. Its expression is down-regulated in many cell lines, and this down-regulation may be an early and sensitive… More details

$245 / 0.01 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

TAGLN, cDNA Clone

Full Product Name

TAGLN

Product Gene Name

TAGLN cdna clone

Product Synonym Names

SM22; SMCC; TAGLN1; WS3-10

Sequence

Nucleotide Sequence: ATGGCCAACA AGGGTCCTTC CTATGGCATG AGCCGCGAAG TGCAGTCCAA AATCGAGAAG AAGTATGACG AGGAGCTGGA GGAGCGGCTG GTGGAGTGGA TCATAGTGCA GTGTGGCCCT GATGTGGGCC GCCCAGACCG TGGGCGCTTG GGCTTCCAGG TCTGGCTGAA GAATGGCGTG ATTCTGAGCA AGCTGGTGAA CAGCCTGTAC CCTGATGGCT CCAAGCCGGT GAAGGTGCCC GAGAACCCAC CCTCCATGGT CTTCAAGCAG ATGGAGCAGG TGGCTCAGTT CCTGAAGGCG GCTGAGGACT ATGGGGTCAT CAAGACTGAC ATGTTCCAGA CTGTTGACCT CTTTGAAGGC AAAGACATGG CAGCAGTGCA GAGGACCCTG ATGGCTTTGG GCAGCTTGGC AGTGACCAAG AATGATGGGC ACTACCGTGG AGATCCCAAC TGGTTTATGA AGAAAGCGCA GGAGCATAAG AGGGAATTCA CAGAGAGCCA GCTGCAGGAG GGAAAGCATG TCATTGGCCT TCAGATGGGC AGCAACAGAG GGGCCTCCCA GGCCGGCATG ACAGGCTACG GACGACCTCG GCAGATCATC AGTTAG

Transl ation Sequence: MANKGPSYGM SREVQSKIEK KYDEELEERL VEWIIVQCGP DVGRPDRGRL GFQVWLKNGV ILSKLVNSLY PDGSKPVKVP ENPPSMVFKQ MEQVAQFLKA AEDYGVIKTD MFQTVDLFEG KDMAAVQRTL MALGSLAVTK NDGHYRGDPN WFMKKAQEHK REFTESQLQE GKHVIGLQMG SNRGASQAGM TGYGRPRQII S

Form/Format

Lyophilized

Preparation and Storage

Store the plasmid at -20 degree C.

OMIM

600818

3D Structure

ModBase 3D Structure for Q01995

Species

Human

Chromosome Location

11q23.2

OMIM Reference Number

600818

cDNA Size

606bp

Vector Description

This shuttle vector contains the complete ORF. It is inseted BamH I to Xho I. The gene insert contains multiple cloning sites which can be used to easily cut and transfer the gene and recombination site into your expression vector.

Vector

(puc19-derived cloning vector)

Preparation Before Usage

1. Centrifuge at 7000rpm for 1 minute. 2. Carefully open the vial and add 100ul of sterile water to dissolve the DNA. Each tube contains approximately 10ug of lyophilized plasmid.

Product Categories/Family for TAGLN cdna clone

Cytoskeleton; Signal Transduction

Other Notes

Small volumes of TAGLN cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for TAGLN purchase

MBS200649 is a cDNA clone targeting TAGLN.

Additional Details

NCBI/Uniprot data below describe general gene information for TAGLN. It may not necessarily be applicable to this product.

NCBI GI #

48255907

NCBI Accession #

NP_001001522.1

UniProt Primary Accession #

Q01995

GenBank Nucleotide #

NM_001001522

NCBI Official Full Name

transgelin

UniProt Protein Name

Transgelin

UniProt Synonym Protein Names

22 kDa actin-binding protein; Protein WS3-10; Smooth muscle protein 22-alpha

Protein Family

Transgelin

UniProt Gene Name

TAGLN

UniProt Synonym Gene Names

SM22; WS3-10; SM22-alpha

UniProt Entry Name

TAGL_HUMAN

UniProt Comments for TAGLN

TAGLN: Actin cross-linking/gelling protein. Involved in calcium interactions and contractile properties of the cell that may contribute to replicative senescence. Belongs to the calponin family.

Protein type: Nuclear receptor co-regulator; Motility/polarity/chemotaxis; Actin-binding

Chromosomal Location of Human Ortholog: 11q23.2

Cellular Component: cytoplasm

Molecular Function: actin filament binding; protein binding

Biological Process: muscle development; epithelial cell differentiation

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with TAGLN cdna clone

Reference Product	PubMed Publications
SRF cdna clone	>22 publications with TAGLN and SRF
ACTA2 cdna clone	>10 publications with TAGLN and ACTA2
MYOCD cdna clone	>5 publications with TAGLN and MYOCD
MYH11 cdna clone	>4 publications with TAGLN and MYH11
TPM2 cdna clone	>3 publications with TAGLN and TPM2
ELK1 cdna clone	>2 publications with TAGLN and ELK1
CNN1 cdna clone	>1 publications with TAGLN and CNN1
MYL9 cdna clone	>1 publications with TAGLN and MYL9
GATA6 cdna clone	>1 publications with TAGLN and GATA6

Diseases associated with TAGLN cdna clone

Disease Name	Pubmed Publications
Neoplasms Antibodies	>173 publications with TAGLN and Neoplasms
Cardiovascular Diseases Antibodies	>35 publications with TAGLN and Cardiovascular Diseases
Nervous System Diseases Antibodies	>16 publications with TAGLN and Nervous System Diseases
Disease Models, Animal Antibodies	>15 publications with TAGLN and Disease Models, Animal
Brain Diseases Antibodies	>13 publications with TAGLN and Brain Diseases
Kidney Diseases Antibodies	>12 publications with TAGLN and Kidney Diseases
Heart Diseases Antibodies	>12 publications with TAGLN and Heart Diseases
Hyperplasia Antibodies	>9 publications with TAGLN and Hyperplasia
Liver Diseases Antibodies	>8 publications with TAGLN and Liver Diseases
Liver Neoplasms Antibodies	>8 publications with TAGLN and Liver Neoplasms

Organs/Tissues associated with TAGLN cdna clone

Organ/Tissue Name	Pubmed Publications
Muscle Antibodies	>351 publications with TAGLN and Muscle
Vascular Antibodies	>105 publications with TAGLN and Vascular
Blood Antibodies	>36 publications with TAGLN and Blood
Heart Antibodies	>35 publications with TAGLN and Heart
Lung Antibodies	>26 publications with TAGLN and Lung
Bone Antibodies	>20 publications with TAGLN and Bone
Embryonic Tissue Antibodies	>20 publications with TAGLN and Embryonic Tissue
Lymph Antibodies	>19 publications with TAGLN and Lymph
Lymph Node Antibodies	>19 publications with TAGLN and Lymph Node
Liver Antibodies	>14 publications with TAGLN and Liver