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TBX18 cDNA Clone – T-Box 18 (Human)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1271468

MBS1271468 is a cDNA clone targeting TBX18. More details

$400 / 0.01 mg Plasmid + 0.2 mL Glycerol-Stock +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
TBX18, cDNA Clone
Full Product Name
TBX18 cDNA Clone
Product Gene Name
TBX18 cdna clone
Sequence
atggccgaga agcgaagggg ctcgccgtgc agcatgctaa gcctcaaggc gcacgctttc tcggtggagg cgctgatcgg cgccgagaag cagcaacagc ttcagaagaa gcggcgaaaa ctgggcgccg aagaggcggc gagggccgtg gacgacggag gctgcagccg cggcggcggc gcgggcgaaa agggttcttc tgagggagac gaaggcgctg cgctcccgcc gccggctggg gcgacgtctg ggccggctcg gagtggcgca gacctggagc gcggagccgc gggcggctgt gaggacggct tccagcaggg agcttcccct ctggcgtcac cgggaggctc ccccaagggg tctccggcgc gctccctggc ccggcccggg acccctctgc cctcgccgca ggccccgcgg gtggatctgc agggagccga gctctggaag cgctttcatg agataggcac tgagatgatc atcaccaagg ccggcaggcg catgtttcca gcaatgagag tgaagatctc tggattagat cctcaccagc aatattacat tgccatggat attgtaccag tggacaacaa aagatacagg tatgtttacc acagttcgaa atggatggtg gcaggtaatg ctgactcgcc tgtgccaccc cgtgtgtaca ttcatccaga ctcgcctgcc tcgggggaga cttggatgag acaagttatc agcttcgaca agctgaagct caccaacaat gaactggatg accaaggcca tattattctt cattctatgc acaaatacca accgcgagtg cacgtcatcc gtaaagactg tggagacgat ctttctccca tcaagcctgt tccatccggg gagggagtaa aggcattctc ctttccagaa actgtcttca caaccgtcac tgcctatcag aatcagcaga ttactcgcct gaagatagat aggaatccat ttgctaaagg cttccgagac tccgggcgca acagaatggg tttggaagcc ttggtggaat catatgcatt ctggcgacca tcactacgga ctctgacctt tgaagatatc cctggaattc ccaagcaagg caatgcaagt tcctccacct tgctccaagg tactgggaat ggcgttcctg ccactcaccc tcaccttttg tctggctcct cttgctcctc tcctgccttc catctggggc ccaacaccag ccagctgtgt agtctggccc ctgctgacta ttctgcctgt gcccgctcag gcctcaccct caaccgatac agcacatctt tggcagagac ctacaacagg ctcaccaacc aggctggtga gacctttgcc ccgcccagga ctccctccta tgtgggcgtg agcagcagca cctccgtgaa catgtccatg ggtggcactg atggggacac cttcagctgc ccacagacca gcttatccat gcagatttcg ggaatgtccc cccagctcca gtatatcatg ccatcaccct ccagcaatgc cttcgccact aaccagaccc atcagggttc ctataatact tttagattac acagcccctg tgcactatat ggatataact tctccacatc ccccaaactg gctgccagtc ctgagaaaat tgtttcttcc caaggaagtt tcttggggtc ctcaccgagt gggaccatga cggatcggca gatgttgccc cctgtggaag gagtgcacct gcttagcagt gggggtcagc agagtttctt tgactctagg accctaggaa gcttaactct gtcatcatct caagtatctg cacatatggt ctga
Molecular Weight
64,753 Da
OMIM
143400
Vector
pUC
Clone Sequence Report
Provided with product shipment
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of TBX18 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for TBX18. It may not necessarily be applicable to this product.

NCBI GI #
124376545
NCBI GeneID
9096
NCBI Accession #
BC132715
UniProt Secondary Accession #
Q7Z6U4; Q9UJI6; A2RU13
UniProt Related Accession #
O95935
NCBI Official Full Name
Homo sapiens T-box 18, mRNA
NCBI Official Synonym Full Names
T-box 18
NCBI Official Symbol
TBX18
NCBI Official Synonym Symbols
CAKUT2
UniProt Protein Name
T-box transcription factor TBX18
Protein Family
T-box transcription factor
UniProt Gene Name
TBX18
UniProt Synonym Gene Names
T-box protein 18
UniProt Entry Name
TBX18_HUMAN
NCBI Protein Information
T-box transcription factor TBX18

NCBI Summary for TBX18

This genes codes for a member of an evolutionarily conserved family of transcription factors that plays a crucial role in embryonic development. The family is characterized by the presence of the DNA-binding T-box domain and is divided into five sub-families based on sequence conservation in this domain. The encoded protein belongs to the vertebrate specific Tbx1 sub-family. The protein acts as a transcriptional repressor by antagonizing transcriptional activators in the T-box family. The protein forms homo- or heterodimers with other transcription factors of the T-box family or other transcription factors. [provided by RefSeq, Nov 2012]
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UniProt Comments for TBX18

TBX18: Probable transcriptional regulator involved in developmental processes.

Protein type: Transcription factor; DNA-binding

Chromosomal Location of Human Ortholog: 6q14-q15

Cellular Component: nucleus

Molecular Function: protein binding; protein heterodimerization activity; protein homodimerization activity

Disease: Congenital Anomalies Of Kidney And Urinary Tract 2; Huntington Disease
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Research Articles on TBX18

1. Mutations in TBX18 cause dominant urinary tract malformations via transcriptional dysregulation of ureter development.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Diseases associated with TBX18 cdna clone

 Disease Name  Pubmed Publications
 Congenital Abnormalities Antibodies  >8 publications with TBX18 and Congenital Abnormalities
 Heart Diseases Antibodies  >8 publications with TBX18 and Heart Diseases
 Kidney Diseases Antibodies  >5 publications with TBX18 and Kidney Diseases
 Musculoskeletal Diseases Antibodies  >2 publications with TBX18 and Musculoskeletal Diseases
 Fetal Death Antibodies  >1 publications with TBX18 and Fetal Death
 Nervous System Diseases Antibodies  >1 publications with TBX18 and Nervous System Diseases
 Musculoskeletal Abnormalities Antibodies  >1 publications with TBX18 and Musculoskeletal Abnormalities
 Necrosis Antibodies  >1 publications with TBX18 and Necrosis

Organs/Tissues associated with TBX18 cdna clone

 Organ/Tissue Name  Pubmed Publications
 Muscle Antibodies  >40 publications with TBX18 and Muscle
 Embryonic Tissue Antibodies  >39 publications with TBX18 and Embryonic Tissue
 Vascular Antibodies  >14 publications with TBX18 and Vascular
 Bone Antibodies  >13 publications with TBX18 and Bone
 Kidney Antibodies  >7 publications with TBX18 and Kidney
 Skin Antibodies  >3 publications with TBX18 and Skin
 Lung Antibodies  >3 publications with TBX18 and Lung
 Connective Tissue Antibodies  >2 publications with TBX18 and Connective Tissue
 Liver Antibodies  >2 publications with TBX18 and Liver
 Ear Antibodies  >2 publications with TBX18 and Ear
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