Human TES cDNA Clone Expression Plasmid – Cat# MBS1267277

TES cDNA Clone – Testis Derived Transcript (3 LIM Domains) (Human)

Name: TES cDNA Clone; Human; MyBioSource
Brand: MyBioSource
SKU: MBS1267277
Price: 505 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1267277

MBS1267277 is a cDNA clone targeting TES. More details

$505 / 0.01 mg Plasmid + 0.2 mL Glycerol-Stock +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

TES, cDNA Clone

Full Product Name

TES cDNA Clone

Product Gene Name

TES cdna clone

Sequence

atggacctgg aaaacaaagt gaagaagatg ggcttaggtc acgagcaagg atttggagcc ccttgtttaa aatgcaaaga aaaatgtgaa ggattcgaac tgcacttctg gagaaaaata tgtcgtaact gcaagtgtgg ccaagaagag catgatgtcc tcttgagcaa tgaagaggat cgaaaagtgg gaaaactttt tgaagacacc aagtatacca ctctgattgc aaaactaaag tcagatggaa ttcccatgta taaacgcaat gttatgatat tgacgaatcc agttgctgcc aagaagaatg tctccatcaa tacagttacc tatgagtggg ctcctcctgt ccagaatcaa gcattggcca ggcagtacat gcagatgcta cccaaggaaa agcagccagt agcaggctca gagggggcac agtaccggaa gaagcagctg gcaaagcagc tccctgcaca tgaccaggac ccttcaaagt gccatgagtt gtctcccaga gaggtgaagg agatggagca gtttgtgaag aaatataaga gcgaagctct gggagtagga gatgtcaaac ttccctgtga gatggatgcc caaggcccca aacaaatgaa cattcctgga ggggatagaa gcaccccagc agcagtgggg gccatggagg acaaatctgc tgagcacaaa agaactcaat attcctgcta ttgctgcaaa ctgagtatga aagaaggtga cccagccatc tatgccgaaa gggctggcta tgataaactg tggcacccag cttgttttgt ctgcagcacc tgccatgaac tcctggttga catgatttat ttttggaaga atgagaagct atactgtggc agacattact gtgacagcga gaaaccccga tgtgctggct gtgacgagct gatattcagc aatgagtata cccaggcaga aaaccagaat tggcacctga aacacttctg ctgctttgac tgtgatagca ttctagctgg ggagatatac gtgatggtca atgacaagcc cgtgtgcaag ccctgctatg tgaagaatca cgctgtggtg tgtcaaggat gccacaatgc catcgaccca gaagtgcagc gggtgaccta taacaatttc agctggcatg catccacaga gtgctttctg tgctcttgct gcagcaaatg cctcattggg cagaagttca tgccagtaga agggatggtt ttctgttcag tggaatgtaa gaagaggatg tcttag

Molecular Weight

46,910 Da

OMIM

606085

Vector

Please Inquire

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of TES cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for TES. It may not necessarily be applicable to this product.

NCBI GI #

12655188

NCBI GeneID

26136

NCBI Accession #

BC001451

UniProt Secondary Accession #

Q9GZQ1; Q9HAJ9; A4D0U6

UniProt Related Accession #

Q9UGI8

NCBI Official Full Name

Homo sapiens testis derived transcript (3 LIM domains), mRNA

NCBI Official Synonym Full Names

testin LIM domain protein

NCBI Official Symbol

TES

NCBI Official Synonym Symbols

TESS; TESS-2

UniProt Protein Name

Testin

UniProt Synonym Protein Names

TESS

Protein Family

Terpinolene synthase

UniProt Gene Name

TES

UniProt Entry Name

TES_HUMAN

NCBI Protein Information

testin

NCBI Summary for TES

Cancer-associated chromosomal changes often involve regions containing fragile sites. This gene maps to a commom fragile site on chromosome 7q31.2 designated FRA7G. This gene is similar to mouse Testin, a testosterone-responsive gene encoding a Sertoli cell secretory protein containing three LIM domains. LIM domains are double zinc-finger motifs that mediate protein-protein interactions between transcription factors, cytoskeletal proteins and signaling proteins. This protein is a negative regulator of cell growth and may act as a tumor suppressor. This scaffold protein may also play a role in cell adhesion, cell spreading and in the reorganization of the actin cytoskeleton. Multiple protein isoforms are encoded by transcript variants of this gene.[provided by RefSeq, Mar 2011]

UniProt Comments for TES

TES: Scaffold protein that may play a role in cell adhesion, cell spreading and in the reorganization of the actin cytoskeleton. Plays a role in the regulation of cell proliferation. May act as a tumor suppressor. Inhibits tumor cell growth. Belongs to the prickle / espinas / testin family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Motility/polarity/chemotaxis; Cytoskeletal

Chromosomal Location of Human Ortholog: 7q31.2

Cellular Component: cell junction; cell-cell adherens junction; cytoplasm; focal adhesion; nucleus; plasma membrane; protein complex

Molecular Function: protein binding; zinc ion binding

Biological Process: negative regulation of cell proliferation

Research Articles on TES

1. we confirm that the TES promoter is unmethylated in normal adult and fetal tissues. Re-expression of TESTIN protein in acute lymphoblastic leukemia cells using expression plasmid transfection results in rapid cell death or cell cycle arrest.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Diseases associated with TES cdna clone

Disease Name	Pubmed Publications
Neoplasms Antibodies	>217 publications with TES and Neoplasms
Nervous System Diseases Antibodies	>187 publications with TES and Nervous System Diseases
Cardiovascular Diseases Antibodies	>153 publications with TES and Cardiovascular Diseases
Brain Diseases Antibodies	>102 publications with TES and Brain Diseases
Immune System Diseases Antibodies	>62 publications with TES and Immune System Diseases
Liver Diseases Antibodies	>35 publications with TES and Liver Diseases
Disease Models, Animal Antibodies	>33 publications with TES and Disease Models, Animal
Hemorrhage Antibodies	>26 publications with TES and Hemorrhage
Drug Toxicity Antibodies	>25 publications with TES and Drug Toxicity
Liver Neoplasms Antibodies	>25 publications with TES and Liver Neoplasms

Organs/Tissues associated with TES cdna clone

Organ/Tissue Name	Pubmed Publications
Liver Antibodies	>68 publications with TES and Liver
Lung Antibodies	>49 publications with TES and Lung
Testis Antibodies	>48 publications with TES and Testis
Intestine Antibodies	>37 publications with TES and Intestine
Pancreas Antibodies	>7 publications with TES and Pancreas
Placenta Antibodies	>7 publications with TES and Placenta