Human TKT cDNA Clone Expression Plasmid – Cat# MBS1270797

TKT cDNA Clone – Transketolase (Human)

Name: TKT cDNA Clone; Transketolase; Human; MyBioSource
Brand: MyBioSource
SKU: MBS1270797
Price: 720 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1270797

MBS1270797 is a cDNA clone targeting TKT. More details

$720 / 0.01 mg Plasmid + 0.2 mL Glycerol-Stock +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

TKT, cDNA Clone

Full Product Name

TKT cDNA Clone

Product Gene Name

TKT cdna clone

Sequence

atggagagct accacaagcc tgaccagcag aagctgcagg ccttgaagga cacggccaac cgcctacgta tcagctccat ccaggccacc actgcggcgg gctctggcca ccccacgtca tgctgcagcg ccgcagagat catggctgtc ctctttttcc acaccatgcg ctacaagtcc caggaccccc ggaatccgca caatgaccgc tttgtgctct ccaagggcca tgcagctccc atcctctacg cggtctgggc tgaagctggt ttcctggccg aggcggagct gctgaacctg aggaagatca gctccgactt ggacgggcac ccggtcccga aacaagcttt caccgacgtg gccactggct ccctgggcca gggcctcggg gccgcttgtg ggatggccta caccggcaaa tacttcgaca aggccagcta ccgagtctat tgcttgctgg gagatgggga gctgtcagag ggctctgtat gggaggccat ggccttcgcc agcatctata agctggacaa ccttgtggcc attctagaca tcaatcgcct gggccagagt gacccggccc cgctgcagca ccagatggac atctaccaga agcggtgcga ggccttcggt tggcatgcca tcatcgtgga tggacacagc gtggaggagc tgtgcaaggc ctttggccag gccaagcacc agccaacagc catcattgcc aagaccttca agggccgagg gatcacgggg gtagaagata aggagtcttg gcatgggaag cccctcccca aaaacatggc tgagcagatc atccaggaga tctacagcca gatccagagc aaaaagaaga tcctggcaac ccctccacag gaggacgcac cctcagtgga cattgccaac atccgcatgc ccagcctgcc cagctacaaa gttggggaca agatagccac ccgcaaggcc tacgggcagg cactggccaa gctgggccat gccagtgacc gcatcatcgc cctggatggg gacaccaaaa attccacctt ctcggagatc ttcaaaaagg agcacccgga ccgcttcatc gagtgctaca ttgccgagca gaacatggtg agcatcgcgg tgggctgtgc cacccgcaac aggacggtgc ccttctgcag cacttttgca gccttcttca cgcgggcctt tgaccagatt cgcatggccg ccatctccga gagcaacatc aacctctgcg gctcccactg cggcgtttcc atcggggaag acgggccctc ccagatggcc ctagaagatc tggctatgtt tcggtcagtc cccacatcaa ctgtctttta cccaagtgat ggcgttgcta cagagaaggc agtggaacta gccgccaata caaagggtat ctgcttcatc cggaccagcc gcccagaaaa tgccatcatc tataacaaca atgaggactt ccaggtcgga caagccaagg tggtcctgaa gagcaaggat gaccaggtga ccgttatcgg ggctggggtg accctgcacg aggccttggc cgctgccgaa ctgctgaaga aagaaaagat caacatccgc gtgctggacc ccttcaccat caagcccctg gacagaaaac tcattctcga cagcgctcgt gccaccaagg gcaggatcct caccgtggag gaccattatt atgaaggtgg cattggtgag gctgtgtcca gtgcagtagt gggcgagcct ggcatcactg tcacccacct ggcagttaac cgggtaccaa gaagtgggaa gccagctgag ctgctgaaga tgtttggtat cgacagggat gccattgcac aagctgtgag gggcctcatc accaaggcct ag

Molecular Weight

68,814 Da

OMIM

606781

Vector

Please Inquire

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of TKT cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for TKT. It may not necessarily be applicable to this product.

NCBI GI #

33874807

NCBI GeneID

7086

NCBI Accession #

BC009970

UniProt Secondary Accession #

Q8TBA3; Q96HH3; A8K089; B4DE31; E7EPA7

UniProt Related Accession #

P29401

NCBI Official Full Name

Homo sapiens transketolase, mRNA

NCBI Official Synonym Full Names

transketolase

NCBI Official Symbol

TKT

NCBI Official Synonym Symbols

TK; TKT1; SDDHD; HEL107; HEL-S-48

UniProt Protein Name

Transketolase

Protein Family

Transketolase

UniProt Gene Name

TKT

UniProt Synonym Gene Names

UniProt Entry Name

TKT_HUMAN

NCBI Protein Information

transketolase

NCBI Summary for TKT

This gene encodes a thiamine-dependent enzyme which plays a role in the channeling of excess sugar phosphates to glycolysis in the pentose phosphate pathway. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Apr 2012]

UniProt Comments for TKT

TKT: Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. Homodimer. Belongs to the transketolase family.

Protein type: Carbohydrate Metabolism - pentose phosphate pathway; Transferase; EC 2.2.1.1

Chromosomal Location of Human Ortholog: 3p14.3

Cellular Component: cytosol; nucleoplasm; nucleus; peroxisome; vesicle

Molecular Function: cofactor binding; protein binding; protein homodimerization activity; transketolase activity

Biological Process: glyceraldehyde-3-phosphate biosynthetic process; pentose-phosphate shunt; xylulose biosynthetic process

Disease: Short Stature, Developmental Delay, And Congenital Heart Defects

Research Articles on TKT

1. transketolase (TKT)is required for cancer growth because of its ability to affect the production of NAPDH to counteract oxidative stress.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with TKT cdna clone

Products by Pathway	Pathway Diagram
Biosynthesis Of Amino Acids Pathway antibodies	Biosynthesis Of Amino Acids Pathway Diagram
Biosynthesis Of Amino Acids Pathway antibodies	Biosynthesis Of Amino Acids Pathway Diagram
Insulin Effects Increased Synthesis Of Xylulose-5-Phosphate Pathway antibodies	Insulin Effects Increased Synthesis Of Xylulose-5-Phosphate Pathway Diagram
Integration Of Energy Metabolism Pathway antibodies	Integration Of Energy Metabolism Pathway Diagram
Metabolism Pathway antibodies	Metabolism Pathway Diagram
Metabolism Of Carbohydrates Pathway antibodies	Metabolism Of Carbohydrates Pathway Diagram
Pentose Phosphate Pathway antibodies	Pentose Phosphate Pathway Diagram
Pentose Phosphate Pathway antibodies	Pentose Phosphate Pathway Diagram
Pentose Phosphate Pathway antibodies	Pentose Phosphate Pathway Diagram
Pentose Phosphate Pathway (Pentose Phosphate Cycle) antibodies	Pentose Phosphate Pathway (Pentose Phosphate Cycle) Diagram

Diseases associated with TKT cdna clone

Disease Name	Pubmed Publications
Neoplasms Antibodies	>27 publications with TKT and Neoplasms
Carcinoma Antibodies	>18 publications with TKT and Carcinoma
Adenocarcinoma Antibodies	>8 publications with TKT and Adenocarcinoma
Kidney Diseases Antibodies	>6 publications with TKT and Kidney Diseases
Nervous System Diseases Antibodies	>6 publications with TKT and Nervous System Diseases
Congenital Abnormalities Antibodies	>5 publications with TKT and Congenital Abnormalities
Liver Diseases Antibodies	>5 publications with TKT and Liver Diseases
Liver Neoplasms Antibodies	>4 publications with TKT and Liver Neoplasms
Abnormalities, Drug-Induced Antibodies	>3 publications with TKT and Abnormalities, Drug-Induced
Fatty Liver Antibodies	>3 publications with TKT and Fatty Liver

Organs/Tissues associated with TKT cdna clone

Organ/Tissue Name	Pubmed Publications
Eye Antibodies	>14 publications with TKT and Eye
Liver Antibodies	>13 publications with TKT and Liver
Blood Antibodies	>13 publications with TKT and Blood
Kidney Antibodies	>11 publications with TKT and Kidney
Connective Tissue Antibodies	>8 publications with TKT and Connective Tissue
Mouth Antibodies	>7 publications with TKT and Mouth
Bone Antibodies	>6 publications with TKT and Bone
Brain Antibodies	>6 publications with TKT and Brain
Heart Antibodies	>4 publications with TKT and Heart
Skin Antibodies	>4 publications with TKT and Skin