• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

TPX2 cDNA Clone – TPX2, Microtubule-Associated, Homolog (Xenopus Laevis) (Human)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1277377

MBS1277377 is a cDNA clone targeting TPX2. More details

$840 / 0.01 mg Plasmid + 0.2 mL Glycerol-Stock +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
TPX2, cDNA Clone
Full Product Name
TPX2 cDNA Clone
Product Gene Name
TPX2 cdna clone
Sequence
atgtcacaag ttaaaagctc ttattcctat gatgccccct cggatttcat caatttttca tccttggatg atgaaggaga tactcaaaac atagattcat ggtttgagga gaaggccaat ttggagaata agttactggg gaagaatgga actggagggc tttttcaggg caaaactcct ttgagaaagg ctaatcttca gcaagctatt gtcacacctt tgaaaccagt tgacaacact tactacaaag aggcagaaaa agaaaatctt gtggaacaat ccattccgtc aaatgcttgt tcttccctgg aagttgaggc agccatatca agaaaaactc cagcccagcc tcagagaaga tctcttaggc tttctgctca gaaggatttg gaacagaaag aaaagcatca tgtaaaaatg aaagccaaga gatgtgccac tcctgtaatc atcgatgaaa ttctaccctc taagaaaatg aaagtttcta acaacaaaaa gaagccagag gaagaaggca gtgctcatca agatactgct gaaaagaatg catcttcccc agagaaagcc aagggtagac atactgtgcc ttgtatgcca cctgcaaagc agaagtttct aaaaagtact gaggagcaag agctggagaa gagtatgaaa atgcagcaag aggtggtgga gatgcggaaa aagaatgaag aattcaagaa acttgctctg gctggaatag ggcaacctgt gaagaaatca gtgagccagg tcaccaaatc agttgacttc cacttccgca cagatgagcg aatcaaacaa catcctaaga accaggagga atataaggaa gtgaacttta catctgaact acgaaagcat ccttcatctc ctgcccgagt gactaaggga tgtaccattg ttaagccttt caacctgtcc caaggaaaga aaagaacatt tgatgaaaca gtttctacat atgtgcccct tgcacagcaa gttgaagact tccataaacg aacccctaac agatatcatt tgaggagcaa gaaggatgat attaacctgt taccctccaa atcttctgtg accaagattt gcagagaccc acagactcct gtactgcaaa ccaaacaccg tgcacgggct gtgacctgca aaagtacagc agagctggag gctgaggagc tcgagaaatt gcaacaatac aaattcaaag cacgtgaact tgatcccaga atacttgaag gtgggcccat cttgcccaag aaaccacctg tgaaaccacc caccgagcct attggctttg atttggaaat tgagaaaaga atccaggagc gagaatcaaa gaagaaaaca gaggatgaac actttgaatt tcattccaga ccttgcccta ctaagatttt ggaagatgtt gtgggtgttc ctgaaaagaa ggtacttcca atcaccgtcc ccaagtcacc agcctttgca ttgaagaaca gaattcgaat gcccaccaaa gaagatgagg aagaggacga accggtagtg ataaaagctc aacctgtgcc acattatggg gtgcctttta agccccaaat cccagaggca agaactgtgg aaatatgccc tttctcgttt gattctcgag acaaagaacg tcagttacag aaggagaaga aaataaaaga actgcagaaa ggggaggtgc ccaagttcaa ggcacttccc ttgcctcatt ttgacaccat taacctgcca gagaagaagg taaagaatgt gacccagatt gaacctttct gcttggagac tgacagaaga ggtgctctga aggcacagac ttggaagcac cagctggaag aagaactgag acagcagaaa gaagcagctt gtttcaaggc tcgtccaaac accgtcatct ctcaggagcc ctttgttccc aagaaagaga agaaatcagt tgctgagggc ctttctggtt ctctagttca ggaacctttt cagctggcta ctgagaagag agccaaagag cggcaggagc tggagaagag aatggctgag gtagaagccc agaaagccca gcagttggag gaggccagac tacaggagga agagcagaaa aaagaggagc tggccaggct acggagagaa ctggtgcata aggcaaatcc aatacgcaag taccagggtc tggagataaa gtcaagtgac cagcctctga ctgtgcctgt atctcccaaa ttctccactc gattccactg ctaa
Molecular Weight
89,393 Da
OMIM
605917
Vector
Please Inquire
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of TPX2 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for TPX2. It may not necessarily be applicable to this product.

NCBI GI #
13278710
NCBI GeneID
22974
NCBI Accession #
BC004136
UniProt Secondary Accession #
Q96RR5; Q9H1R4; Q9NRA3; Q9UFN9; Q9UL00; Q9Y2M1
UniProt Related Accession #
Q9ULW0
NCBI Official Full Name
Homo sapiens TPX2, microtubule-associated, homolog (Xenopus laevis), mRNA
NCBI Official Synonym Full Names
TPX2, microtubule nucleation factor
NCBI Official Symbol
TPX2
NCBI Official Synonym Symbols
DIL2; p100; DIL-2; HCTP4; FLS353; HCA519; REPP86; C20orf1; C20orf2; GD:C20orf1
UniProt Protein Name
Targeting protein for Xklp2
UniProt Synonym Protein Names
Differentially expressed in cancerous and non-cancerous lung cells 2; DIL-2; Hepatocellular carcinoma-associated antigen 519; Hepatocellular carcinoma-associated antigen 90; Protein fls353; Restricted expression proliferation-associated protein 100; p100
Protein Family
Protein
UniProt Gene Name
TPX2
UniProt Synonym Gene Names
C20orf1; C20orf2; DIL2; HCA519; DIL-2; p100
UniProt Entry Name
TPX2_HUMAN
NCBI Protein Information
targeting protein for Xklp2

UniProt Comments for TPX2

Spindle assembly factor required for normal assembly of mitotic spindles. Required for normal assembly of microtubules during apoptosis. Required for chromatin and/or kinetochore dependent microtubule nucleation. Mediates AURKA localization to spindle microtubules (PubMed:18663142, PubMed:19208764). Activates AURKA by promoting its autophosphorylation at 'Thr-288' and protects this residue against dephosphorylation (PubMed:18663142, PubMed:19208764). TPX2 is inactivated upon binding to importin-alpha (PubMed:26165940). At the onset of mitosis, GOLGA2 interacts with importin-alpha, liberating TPX2 from importin-alpha, allowing TPX2 to activates AURKA kinase and stimulates local microtubule nucleation (PubMed:26165940).
Show more

Research Articles on TPX2

1. expression of both TPX2 and PD-L1 are associated with persistence/recurrence of cervical intraepithelial neoplasia after cervical conization

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with TPX2 cdna clone

 Products by Pathway  Pathway Diagram
 Aurora A Signaling Pathway antibodies  Aurora A Signaling Pathway Diagram
 Gastric Cancer Network 1 Pathway antibodies  Gastric Cancer Network 1 Pathway Diagram
 PLK1 Signaling Events Pathway antibodies  PLK1 Signaling Events Pathway Diagram

Diseases associated with TPX2 cdna clone

 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >40 publications with TPX2 and Neoplasms
 Carcinoma, Squamous Cell Antibodies  >7 publications with TPX2 and Carcinoma, Squamous Cell
 Lung Neoplasms Antibodies  >7 publications with TPX2 and Lung Neoplasms
 Cell Transformation, Neoplastic Antibodies  >6 publications with TPX2 and Cell Transformation, Neoplastic
 Neoplasms, Experimental Antibodies  >5 publications with TPX2 and Neoplasms, Experimental
 Drug Toxicity Antibodies  >4 publications with TPX2 and Drug Toxicity
 Breast Neoplasms Antibodies  >4 publications with TPX2 and Breast Neoplasms
 Neoplasm Metastasis Antibodies  >4 publications with TPX2 and Neoplasm Metastasis
 Ovarian Diseases Antibodies  >4 publications with TPX2 and Ovarian Diseases
 Ovarian Neoplasms Antibodies  >4 publications with TPX2 and Ovarian Neoplasms

Organs/Tissues associated with TPX2 cdna clone

 Organ/Tissue Name  Pubmed Publications
 Lung Antibodies  >11 publications with TPX2 and Lung
 Bone Antibodies  >4 publications with TPX2 and Bone
 Brain Antibodies  >3 publications with TPX2 and Brain
 Lymph Antibodies  >2 publications with TPX2 and Lymph
 Prostate Antibodies  >2 publications with TPX2 and Prostate
 Blood Antibodies  >2 publications with TPX2 and Blood
 Bone Marrow Antibodies  >2 publications with TPX2 and Bone Marrow
 Lymph Node Antibodies  >2 publications with TPX2 and Lymph Node
 Kidney Antibodies  >1 publications with TPX2 and Kidney
 Uterus Antibodies  >1 publications with TPX2 and Uterus
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000