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TRAM1 cDNA Clone – Translocation Associated Membrane Protein 1 (Human)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1277276

MBS1277276 is a cDNA clone targeting TRAM1. More details

$235 / 0.01 mg Plasmid + 0.2 mL Glycerol-Stock +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
TRAM1, cDNA Clone
Full Product Name
TRAM1 cDNA Clone
Product Gene Name
TRAM1 cdna clone
Sequence
atggcgattc gcaagaaaag caccaagagc cccccagtgc tgagccacga attcgtcctg cagaatcacg cggacatcgt ctcctgtgtg gcgatggtct tcctgctggg gctcatgttt gagataacgg caaaagcttc tatcattttt gttactcttc agtacaatgt caccctccca gcaacagaag aacaagctac tgaatcagtg tccctttatt actatggcat caaagatttg gctactgttt tcttctacat gctagtggcg ataattattc atgccgtaat tcaagagtat atgttggata aaattaacag gcgaatgcac ttctccaaaa caaaacacag caagtttaat gaatctggtc agcttagtgc gttctacctt tttgcctgtg tttggggcac attcattctc atctctgaaa actacatctc agacccaact atcttatgga gggcttatcc ccataacctg atgacatttc aaatgaagtt tttctacata tcacagctgg cttactggct tcatgctttt cctgaactct acttccagaa aaccaaaaaa gaagatattc ctcgtcagct tgtctacatt ggtctttacc tcttccacat tgctggagct taccttttga acttgaatca tctaggactt gttcttctgg tgctacatta ttttgttgaa tttcttttcc acatttcccg cctgttttat tttagcaatg aaaagtatca gaaaggattt tctctgtggg cagttctttt tgttttggga agacttctga ctttaattct ttcagtactg actgttggtt ttggccttgc aagagcagaa aatcagaagc tggatttcag tactggaaac ttcaatgtgt tagctgttag aatcgctgtt ctggcatcca tttgcgttac tcaggcattt atgatgtgga agttcattaa ttttcagctt cgaaggtgga gggaacattc tgcttttcag gcaccagctg tgaagaagaa accaacagta actaaaggca gatcttctaa aaaaggaaca gaaaatggtg tgaatggaac attaacttca aatgtagcag actctccccg gaataaaaaa gagaaatctt cataa
Molecular Weight
39,683 Da
OMIM
605190
Vector
pENTR223.1 or pUC
Clone Sequence Report
Provided with product shipment
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of TRAM1 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for TRAM1. It may not necessarily be applicable to this product.

NCBI GI #
33990663
NCBI GeneID
23471
NCBI Accession #
BC000687
UniProt Secondary Accession #
B4E0K2
UniProt Related Accession #
Q15629
NCBI Official Full Name
Homo sapiens translocation associated membrane protein 1, mRNA
NCBI Official Synonym Full Names
translocation associated membrane protein 1
NCBI Official Symbol
TRAM1
NCBI Official Synonym Symbols
TRAM; PNAS8; TRAMP
UniProt Protein Name
Translocating chain-associated membrane protein 1
Protein Family
Translocating chain-associated membrane protein
UniProt Gene Name
TRAM1
UniProt Synonym Gene Names
TRAM
UniProt Entry Name
TRAM1_HUMAN
NCBI Protein Information
translocating chain-associated membrane protein 1

NCBI Summary for TRAM1

This gene encodes a multi-pass membrane protein that is part of the mammalian endoplasmic reticulum. The encoded protein influences glycosylation and facilitates the translocation of secretory proteins across the endoplasmic reticulum membrane by regulating which domains of the nascent polypeptide chain are visible to the cytosol during a translocational pause. [provided by RefSeq, Oct 2009]
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UniProt Comments for TRAM1

TRAM1: Stimulatory or required for the translocation of secretory proteins across the ER membrane. Belongs to the TRAM family.

Protein type: Receptor, misc.; Membrane protein, multi-pass; Transporter; Membrane protein, integral

Chromosomal Location of Human Ortholog: 8q13.3

Cellular Component: endoplasmic reticulum; rough endoplasmic reticulum

Molecular Function: protein binding; receptor activity

Biological Process: cotranslational protein targeting to membrane
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Research Articles on TRAM1

1. TRAM1 protect HepG2 cells from palmitate-induced insulin resistance. The protection of TRAM1 to HepG2 cells is through endoplasmic reticulum stress-JNK pathway.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with TRAM1 cdna clone

 Products by Pathway  Pathway Diagram
 Gene Expression Pathway antibodies  Gene Expression Pathway Diagram
 Metabolism Of Proteins Pathway antibodies  Metabolism Of Proteins Pathway Diagram
 Protein Processing In Endoplasmic Reticulum Pathway antibodies  Protein Processing In Endoplasmic Reticulum Pathway Diagram
 Protein Processing In Endoplasmic Reticulum Pathway antibodies  Protein Processing In Endoplasmic Reticulum Pathway Diagram
 SRP-dependent Cotranslational Protein Targeting To Membrane Pathway antibodies  SRP-dependent Cotranslational Protein Targeting To Membrane Pathway Diagram
 Translation Pathway antibodies  Translation Pathway Diagram

Diseases associated with TRAM1 cdna clone

 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >4 publications with TRAM1 and Neoplasms
 Liver Diseases Antibodies  >2 publications with TRAM1 and Liver Diseases
 Breast Neoplasms Antibodies  >2 publications with TRAM1 and Breast Neoplasms
 Necrosis Antibodies  >2 publications with TRAM1 and Necrosis
 Fatty Liver Antibodies  >1 publications with TRAM1 and Fatty Liver
 Ovarian Neoplasms Antibodies  >1 publications with TRAM1 and Ovarian Neoplasms
 Kidney Diseases Antibodies  >1 publications with TRAM1 and Kidney Diseases
 Prostatic Neoplasms Antibodies  >1 publications with TRAM1 and Prostatic Neoplasms
 Adenocarcinoma Antibodies  >1 publications with TRAM1 and Adenocarcinoma
 Ovarian Diseases Antibodies  >1 publications with TRAM1 and Ovarian Diseases

Organs/Tissues associated with TRAM1 cdna clone

 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >3 publications with TRAM1 and Liver
 Thyroid Antibodies  >2 publications with TRAM1 and Thyroid
 Kidney Antibodies  >2 publications with TRAM1 and Kidney
 Bone Antibodies  >1 publications with TRAM1 and Bone
 Umbilical Cord Antibodies  >1 publications with TRAM1 and Umbilical Cord
 Mouth Antibodies  >1 publications with TRAM1 and Mouth
 Blood Antibodies  >1 publications with TRAM1 and Blood
 Stomach Antibodies  >1 publications with TRAM1 and Stomach
 Vascular Antibodies  >1 publications with TRAM1 and Vascular
 Prostate Antibodies  >1 publications with TRAM1 and Prostate
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