Human TRMT12 cDNA Clone Expression Plasmid – Cat# MBS1271004

TRMT12 cDNA Clone – Trna Methyltransferase 12 Homolog (S. Cerevisiae) (Human)

Name: TRMT12 cDNA Clone; Human; MyBioSource
Brand: MyBioSource
SKU: MBS1271004
Price: 235 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1271004

MBS1271004 is a cDNA clone targeting TRMT12. More details

$235 / 0.01 mg Plasmid + 0.2 mL Glycerol-Stock +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

TRMT12, cDNA Clone

Full Product Name

TRMT12 cDNA Clone

Product Gene Name

TRMT12 cdna clone

Sequence

atgagagaga atgtggttgt tagcaacatg gagagagaaa gtgggaagcc cgtggctgtt gtcgcagttg tgactgagcc tcggtttacc cagcgataca gagaatatct ccagaggcag aaactctttg atacacagca ccgtgtggaa aagatgccgg atggctcggt ggcgctaccg gtgctgggag agacgcttcc agagcagcac ctgcaggagc tgaggaatcg tgttgcccca ggcagtccct gtatgctcac gcagctcccg gatcctgttc cttcgaagag ggcccagggt tgttcacctg cccaaaaatt gtgtcttgag gtgagtcgct gggtggaggg tcggggagtc aagtggtcag ccgagctgga ggctgatttg ccccgatcat ggcaacggca tggtaatctc ttgttgctga gtgaagactg tttccaagcc aagcagtgga aaaatctggg accggaactc tgggagaccg ttgccttggc acttggcgtc cagcgtttgg caaaacgagg gcgggtatca ccggatggta ctcgaactcc agcagtgaca ctgctgctgg gtgaccatgg ctgggtagag catgtggata atggtatccg ttataagttt gacgtgaccc agtgtatgtt ctcctttgga aacatcactg agaagcttcg agtggcatcg ttgtcctgtg ctggagaagt gctggtggat ctctatgcag ggattggtta ttttacattg cctttcctag ttcatgctgg tgctgccttc gtccatgctt gtgagtggaa tccccatgct gtagttgctc tgagaaataa ccttgagatc aatggagtag cagatcggtg ccaaatacac tttggagata acagaaaact gaagctctca aatattgcag atagggtgat cctggggctg attcccagct ctgaagaagg ctggcccatt gcctgccaag tgttaaggca ggatgctgga ggcattttgc atatccacca aaatgtggaa tctttcccag ggaagaatct tcaggctctt ggagtcagca aagtagagaa agagcattgg ctgtatcctc agcaaattac caccaaccaa tggaaaaatg gagctaccag ggattctagg ggaaaaatgc tgtcaccagc caccaagcca gagtggcaaa ggtgggcaga atctgcagaa actcgaatcg ccactcttct tcagcaggtg catgggaaac catggaagac acaaattctg cacatccaac cagtgaaatc ctatgctccc catgtggatc acatagtcct ggatctggaa tgctgcccct gtccttcagt tggctag

Molecular Weight

50,236 Da

OMIM

611244

Vector

pENTR223.1 or pUC

Clone Sequence Report

Provided with product shipment

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of TRMT12 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for TRMT12. It may not necessarily be applicable to this product.

NCBI GI #

33873310

NCBI GeneID

55039

NCBI Accession #

BC011713

UniProt Secondary Accession #

Q6PKB9; Q96F21; Q9NWK6

UniProt Related Accession #

Q53H54

NCBI Official Full Name

Homo sapiens tRNA methyltransferase 12 homolog (S. cerevisiae), mRNA

NCBI Official Synonym Full Names

tRNA methyltransferase 12 homolog

NCBI Official Symbol

TRMT12

NCBI Official Synonym Symbols

TYW2; TRM12

UniProt Protein Name

tRNA wybutosine-synthesizing protein 2 homolog

UniProt Synonym Protein Names

tRNA(Phe) (4-demethylwyosine(37)-C(7)) aminocarboxypropyltransferase

Protein Family

tRNA wybutosine-synthesizing protein

UniProt Gene Name

TRMT12

UniProt Synonym Gene Names

TRM12; TYW2; tRNA-yW-synthesizing protein 2

UniProt Entry Name

TYW2_HUMAN

NCBI Protein Information

tRNA wybutosine-synthesizing protein 2 homolog

NCBI Summary for TRMT12

Wybutosine (yW) is a hypermodified guanosine at the 3-prime position adjacent to the anticodon of phenylalanine tRNA that stabilizes codon-anticodon interactions during decoding on the ribosome. TRMT12 is the human homolog of a yeast gene essential for yW synthesis (Noma and Suzuki, 2006).[supplied by OMIM, Mar 2008]

UniProt Comments for TRMT12

TRMT12: Probable S-adenosyl-L-methionine-dependent transferase that acts as a component of the wybutosine biosynthesis pathway. Wybutosine is a hyper modified guanosine with a tricyclic base found at the 3'-position adjacent to the anticodon of eukaryotic phenylalanine tRNA. Belongs to the TRM5 / TYW2 family.

Protein type: Methyltransferase; EC 2.5.1.114

Chromosomal Location of Human Ortholog: 8q24.13

Molecular Function: protein binding

Research Articles on TRMT12

1. analysis by RT-qPCR using RNA from 30 breast tumors showed TRMT12 was overexpressed >2 fold in 87% of the tumors. TRMT12 is a homologue of a yeast gene encoding a tRNA methyltransferase involved in the posttranscriptional modification of tRNA(Phe)

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Diseases associated with TRMT12 cdna clone

Disease Name	Pubmed Publications
Neoplasms Antibodies	>1 publications with TRMT12 and Neoplasms
Breast Neoplasms Antibodies	>1 publications with TRMT12 and Breast Neoplasms