Human TWF2 cDNA Clone Expression Plasmid – Cat# MBS1270894

TWF2 cDNA Clone – Twinfilin, Actin-Binding Protein, Homolog 2 (Drosophila) (Human)

Name: TWF2 cDNA Clone; Human; MyBioSource
Brand: MyBioSource
SKU: MBS1270894
Price: 235 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1270894

MBS1270894 is a cDNA clone targeting TWF2. More details

$235 / 0.01 mg Plasmid + 0.2 mL Glycerol-Stock +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

TWF2, cDNA Clone

Full Product Name

TWF2 cDNA Clone

Product Gene Name

TWF2 cdna clone

Sequence

atggcgcacc aaacgggcat ccacgccacg gaagagctga aggaattctt tgccaaggca cgggctggct ctgtgcggct catcaaggtt gtgattgagg acgagcagct cgtgctgggt gcctcgcagg agccagtagg ccgctgggat caggactatg acagggccgt gctgccactg ctggacgccc agcagccctg ctacctgctc taccgcctcg actcacagaa tgctcagggc ttcgaatggc tcttcctcgc ctggtcgcct gataactccc ccgtgcggct gaagatgctg tacgcggcca cgcgggccac agtgaaaaag gagtttggag gtggccacat caaggatgag ctcttcggga ctgtgaagga tgacctctct tttgctgggt accagaaaca cctgtcgtcc tgtgcggcac ctgccccgct gacctcggct gagagagagc tccagcagat ccgcattaac gaggtgaaga cagagatcag tgtggaaagc aagcaccaga ccctgcaggg cctcgccttc cccctgcagc ctgaggccca gcgggcactc cagcagctca agcagaaaat ggtcaactac atccagatga agctggacct agagcgggaa accattgagc tggtgcacac agagcccacg gatgtggccc agctgccctc ccgggtgccc cgagatgctg cccgctacca cttcttcctc tacaagcaca cccatgaggg cgaccccctt gagtctgtag tgttcatcta ctccatgccg gggtacaagt gcagcatcaa ggagcgaatg ctctactcca gctgcaagag ccgcctcctc gactccgtgg agcaggactt ccatctggag atcgccaaga aaattgagat tggcgatggg gcagagctga cggcagagtt cctctacgac gaggtgcacc ccaagcaaca cgccttcaag caggccttcg ccaagcccaa gggcccaggg ggcaagcggg gccataagcg cctcatccgc ggcccgggtg aaaatgggga tgacagctag

Molecular Weight

39,548 Da

OMIM

607433

Vector

pENTR223.1 or pUC

Clone Sequence Report

Provided with product shipment

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of TWF2 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for TWF2. It may not necessarily be applicable to this product.

NCBI GI #

13111976

NCBI GeneID

11344

NCBI Accession #

BC003161

UniProt Secondary Accession #

Q9Y3F5

UniProt Related Accession #

Q6IBS0

NCBI Official Full Name

Homo sapiens twinfilin, actin-binding protein, homolog 2 (Drosophila), mRNA

NCBI Official Synonym Full Names

twinfilin actin binding protein 2

NCBI Official Symbol

TWF2

NCBI Official Synonym Symbols

A6r; A6RP; PTK9L; MSTP011

UniProt Protein Name

Twinfilin-2

UniProt Synonym Protein Names

A6-related protein; hA6RP; Protein tyrosine kinase 9-like; Twinfilin-1-like protein

Protein Family

Twinfilin

UniProt Gene Name

TWF2

UniProt Synonym Gene Names

PTK9L; hA6RP

UniProt Entry Name

TWF2_HUMAN

NCBI Protein Information

twinfilin-2

NCBI Summary for TWF2

The protein encoded by this gene was identified by its interaction with the catalytic domain of protein kinase C-zeta. The encoded protein contains an actin-binding site and an ATP-binding site. It is most closely related to twinfilin (PTK9), a conserved actin monomer-binding protein. [provided by RefSeq, Jul 2008]

UniProt Comments for TWF2

A6r: Actin-binding protein involved in motile and morphological processes. Inhibits actin polymerization, likely by sequestering G-actin. By capping the barbed ends of filaments, it also regulates motility. Seems to play an important role in clathrin-mediated endocytosis and distribution of endocytic organelles. May play a role in regulating the mature length of the middle and short rows of stereocilia. Belongs to the actin-binding proteins ADF family. Twinfilin subfamily.

Protein type: Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 3p21.1

Cellular Component: cell-cell adherens junction; cytoplasm; filopodium; growth cone; lamellipodium; myofibril; perinuclear region of cytoplasm; stereocilium

Molecular Function: actin monomer binding; ATP binding; phosphatidylinositol-4,5-bisphosphate binding; protein binding; protein kinase C binding

Biological Process: barbed-end actin filament capping; negative regulation of actin filament polymerization; positive regulation of axon extension; regulation of actin cytoskeleton organization and biogenesis; regulation of microvillus length; sequestering of actin monomers

Research Articles on TWF2

1. Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator)

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with TWF2 cdna clone

Products by Pathway	Pathway Diagram
IGF1R Signaling Cascade Pathway antibodies	IGF1R Signaling Cascade Pathway Diagram
IRS-mediated Signalling Pathway antibodies	IRS-mediated Signalling Pathway Diagram
IRS-related Events Pathway antibodies	IRS-related Events Pathway Diagram
IRS-related Events Triggered By IGF1R Pathway antibodies	IRS-related Events Triggered By IGF1R Pathway Diagram
Immune System Pathway antibodies	Immune System Pathway Diagram
Innate Immune System Pathway antibodies	Innate Immune System Pathway Diagram
Insulin Receptor Signalling Cascade Pathway antibodies	Insulin Receptor Signalling Cascade Pathway Diagram
MyD88 Dependent Cascade Initiated On Endosome Pathway antibodies	MyD88 Dependent Cascade Initiated On Endosome Pathway Diagram
PI3K Cascade Pathway antibodies	PI3K Cascade Pathway Diagram
Signal Transduction Pathway antibodies	Signal Transduction Pathway Diagram

Organs/Tissues associated with TWF2 cdna clone

Organ/Tissue Name	Pubmed Publications
Muscle Antibodies	>2 publications with TWF2 and Muscle
Heart Antibodies	>2 publications with TWF2 and Heart