Human TYMP cDNA Clone Expression Plasmid – Cat# MBS1265698

TYMP cDNA Clone – Thymidine Phosphorylase (Human)

Name: TYMP cDNA Clone; Thymidine Phosphorylase; Human; MyBioSource
Brand: MyBioSource
SKU: MBS1265698
Price: 235 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1265698

MBS1265698 is a cDNA clone targeting TYMP. More details

$235 / 0.01 mg Plasmid + 0.2 mL Glycerol-Stock +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

TYMP, cDNA Clone

Full Product Name

TYMP cDNA Clone

Product Gene Name

TYMP cdna clone

Sequence

atggcagcct tgatgacccc gggaaccggg gccccacccg cgcctggtga cttctccggg gaagggagcc agggacttcc cgacccttcg ccagagccca agcagctccc ggagctgatc cgcatgaagc gagacggagg ccgcctgagc gaagcggaca tcaggggctt cgtggccgct gtggtgaatg ggagcgcgca gggcgcacag atcggggcca tgctgatggc catccgactt cggggcatgg atctggagga gacctcggtg ctgacccagg ccctggctca gtcgggacag cagctggagt ggccagaggc ctggcgccag cagcttgtgg acaagcattc cacagggggt gtgggtgaca aggtcagcct ggtcctcgca cctgccctgg cggcatgtgg ctgcaaggtg ccaatgatca gcggacgtgg tctggggcac acaggaggca ccttggataa gctggagtct attcctggat tcaatgtcat ccagagccca gagcagatgc aagtgctgct ggaccaggcg ggctgctgta tcgtgggtca gagtgagcag ctggttcctg cggacggaat cctatatgca gccagagatg tgacagccac cgtggacagc ctgccactca tcacagcctc cattctcagt aagaaactcg tggaggggct gtccgctctg gtggtggacg ttaagttcgg aggggccgcc gtcttcccca accaggagca ggcccgggag ctggcaaaga cgctggttgg cgtgggagcc agcctagggc ttcgggtcgc ggcagcgctg accgccatgg acaagcccct gggtcgctgc gtgggccacg ccctggaggt ggaggaggcg ctgctctgca tggacggcgc aggcccgcca gacttaaggg acctggtcac cacgctcggg ggcgccctgc tctggctcag cggacacgcg gggactcagg cccagggcgc tgcccgggtg gccgcggcgc tggacgacgg ctcggccctt ggccgcttcg agcggatgct ggcggcgcag ggcgtggatc ccggtctggc ccgagccctg tgctcgggaa gtcccgcaga acgccggcag ctgctgcctc gcgcccggga gcaggaggag ctgctggcgc ccgcagatgg caccgtggag ctggtccggg cgctgccgct ggcgctggtg ctgcacgagc tcggggccgg gcgcagccgc gctggggagc cgctccgcct gggggtgggc gcagagctgc tggtcgacgt gggtcagagg ctgcgccgtg ggaccccctg gctccgcgtg caccgggacg gccccgcgct cagcggcccg cagagccgcg ccctgcagga ggcgctcgta ctctccgacc gcgcgccatt cgccgccccc ttgcccttcg cagagctcgt tctgccgccg cagcaataa

Molecular Weight

50,405 Da

OMIM

131222

Vector

pENTR223.1 or pUC

Clone Sequence Report

Provided with product shipment

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of TYMP cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for TYMP. It may not necessarily be applicable to this product.

NCBI GI #

31324963

NCBI GeneID

1890

NCBI Accession #

BC052211

UniProt Secondary Accession #

Q13390; Q8WVB7; A8MW15; H9KVA0

UniProt Related Accession #

P19971

NCBI Official Full Name

Homo sapiens thymidine phosphorylase, mRNA

NCBI Official Synonym Full Names

thymidine phosphorylase

NCBI Official Symbol

TYMP

NCBI Official Synonym Symbols

TP; ECGF; ECGF1; MNGIE; MEDPS1; MTDPS1; PDECGF; hPD-ECGF

UniProt Protein Name

Thymidine phosphorylase

UniProt Synonym Protein Names

Gliostatin; Platelet-derived endothelial cell growth factor; PD-ECGF; TdRPase

UniProt Gene Name

TYMP

UniProt Synonym Gene Names

ECGF1; TP; PD-ECGF

UniProt Entry Name

TYPH_HUMAN

NCBI Protein Information

thymidine phosphorylase

NCBI Summary for TYMP

This gene encodes an angiogenic factor which promotes angiogenesis in vivo and stimulates the in vitro growth of a variety of endothelial cells. It has a highly restricted target cell specificity acting only on endothelial cells. Mutations in this gene have been associated with mitochondrial neurogastrointestinal encephalomyopathy. Multiple alternatively spliced transcript variants have been identified. [provided by RefSeq, Apr 2012]

UniProt Comments for TYMP

ECGF1: May have a role in maintaining the integrity of the blood vessels. Has growth promoting activity on endothelial cells, angiogenic activity in vivo and chemotactic activity on endothelial cells in vitro. Homodimer. Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.

Protein type: Nucleotide Metabolism - pyrimidine; Transferase; Phosphorylase; Motility/polarity/chemotaxis; EC 2.4.2.4; DNA replication; Cytokine; Xenobiotic Metabolism - drug metabolism - other enzymes

Chromosomal Location of Human Ortholog: 22q13.33

Cellular Component: cytosol

Molecular Function: phosphorylase activity; platelet-derived growth factor receptor binding; transferase activity, transferring pentosyl groups

Biological Process: DNA replication; mitochondrial genome maintenance; pyrimidine nucleoside catabolic process; pyrimidine nucleoside salvage; pyrimidine nucleotide metabolic process

Disease: Mitochondrial Dna Depletion Syndrome 1 (mngie Type)

Research Articles on TYMP

1. Gastrointestinal cancer patient carriers of the thymidine phosphorylase rs11479 T allele, with a low platelet count, could be at risk of a poor outcome.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with TYMP cdna clone

Products by Pathway	Pathway Diagram
Bladder Cancer Pathway antibodies	Bladder Cancer Pathway Diagram
Bladder Cancer Pathway antibodies	Bladder Cancer Pathway Diagram
Drug Metabolism - Other Enzymes Pathway antibodies	Drug Metabolism - Other Enzymes Pathway Diagram
Drug Metabolism - Other Enzymes Pathway antibodies	Drug Metabolism - Other Enzymes Pathway Diagram
Fluoropyrimidine Activity Pathway antibodies	Fluoropyrimidine Activity Pathway Diagram
Metabolism Pathway antibodies	Metabolism Pathway Diagram
Metabolism Of Nucleotides Pathway antibodies	Metabolism Of Nucleotides Pathway Diagram
Pyrimidine Catabolism Pathway antibodies	Pyrimidine Catabolism Pathway Diagram
Pyrimidine Metabolism Pathway antibodies	Pyrimidine Metabolism Pathway Diagram
Pyrimidine Metabolism Pathway antibodies	Pyrimidine Metabolism Pathway Diagram

Diseases associated with TYMP cdna clone

Disease Name	Pubmed Publications
Nervous System Diseases Antibodies	>21 publications with TYMP and Nervous System Diseases
Brain Diseases Antibodies	>20 publications with TYMP and Brain Diseases
Neoplasms Antibodies	>19 publications with TYMP and Neoplasms
Carcinoma Antibodies	>7 publications with TYMP and Carcinoma
Mitochondrial neurogastrointestinal encephalopathy syndrome Antibodies	>6 publications with TYMP and Mitochondrial neurogastrointestinal encephalopathy syndrome
Colorectal Neoplasms Antibodies	>6 publications with TYMP and Colorectal Neoplasms
Adenocarcinoma Antibodies	>5 publications with TYMP and Adenocarcinoma
Diarrhea Antibodies	>4 publications with TYMP and Diarrhea
Vomiting Antibodies	>4 publications with TYMP and Vomiting
Pain Antibodies	>3 publications with TYMP and Pain

Organs/Tissues associated with TYMP cdna clone

Organ/Tissue Name	Pubmed Publications
Muscle Antibodies	>16 publications with TYMP and Muscle
Blood Antibodies	>12 publications with TYMP and Blood
Liver Antibodies	>9 publications with TYMP and Liver
Brain Antibodies	>9 publications with TYMP and Brain
Skin Antibodies	>4 publications with TYMP and Skin
Nerve Antibodies	>4 publications with TYMP and Nerve
Lung Antibodies	>2 publications with TYMP and Lung
Heart Antibodies	>2 publications with TYMP and Heart
Eye Antibodies	>2 publications with TYMP and Eye
Mammary Gland Antibodies	>1 publications with TYMP and Mammary Gland