• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

UBE3C cDNA Clone – Ubiquitin Protein Ligase E3C (Human)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1267850

MBS1267850 is a cDNA clone targeting UBE3C. More details

$235 / 0.01 mg Plasmid + 0.2 mL Glycerol-Stock +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
UBE3C, cDNA Clone
Full Product Name
UBE3C cDNA Clone
Product Gene Name
UBE3C cdna clone
Sequence
atgttcagct tcgaaggcga cttcaagacg cggcccaagg tgtcccttgg cggcgcgagc aggaagtatt ccatccaaag aagtgcattt gatcgctgtg ctaccttgtc acagtccggg ggcgcttttc ccattgctaa tggccccaac cttacccttt tggtaaggca gcttctgttt ttttacaaac aaaatgaaga ctcaaaacgt ttgatatggc tgtatcagaa cttaattaaa cacagctctc tgtttgtcaa gcagttggat ggatctgaga gacttacatg cttatttcag ataaaaagat tgatgagcct ctgttgcagg ttgctgcaaa actgtaatga tgacagtttg aatgttgcac ttccaatgag aatgcttgaa gtattttcgt ctgagaatac ttacttgcct gttttacaag atgctagcta tgtggtgtca gtgattgaac aaattttgca ctacatgatt cacaatgggt attataggtc tctatatttg ttgattaaca gcaagcttcc atcaagtatt gaatattctg atttatctcg agttcctata gcaaaaattt tgctagagaa tgttctaaaa ccattgcact ttacttacaa ctcctgtccg gaaggtgcga ggcaacaagt ttttacagcc ttcacagagg agtttctggc agcacctttt acagatcaga tttttcattt catcattccg gcgcttgcag atgcgcagac cgttttccct tacgagccct ttctgaatgc actgttgtta atagagagta gatgttcaag aaagagtggt ggagcaccct ggcttttcta tttcgtttta actgttggcg aaaattattt gggggccctc tctgaggaag ggctgctggt gtatttgcgg gtgctgcaga ccttcctctc tcagttacca gtctctcctg ccagcgcgag ctgtcacgac tcagccagtg actctgagga ggagagtgaa gaagccgaca agccctcaag cccggaggat ggcagactgt cagtatcata cataacagag gaatgcctga agaagctgga cacaaagcag cagaccaaca ccctgctcaa cctggtgtgg agggactctg cgagcgagga ggtcttcacc accatggcct ccgtctgcca cacgctgatg gtgcagcacc gcatgatggt acccaaagtc agggtgtaca aatga
Molecular Weight
45,845 Da
OMIM
614454
Vector
pENTR223.1
Clone Sequence Report
Provided with product shipment
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of UBE3C cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for UBE3C. It may not necessarily be applicable to this product.

NCBI GI #
20072204
NCBI GeneID
9690
NCBI Accession #
BC026241
UniProt Secondary Accession #
Q8TC15; Q96CR4; Q9UDU3; A4D235; A6NCP3
UniProt Related Accession #
Q15386
NCBI Official Full Name
Homo sapiens ubiquitin protein ligase E3C, mRNA
NCBI Official Synonym Full Names
ubiquitin protein ligase E3C
NCBI Official Symbol
UBE3C
NCBI Official Synonym Symbols
HECTH2
UniProt Protein Name
Ubiquitin-protein ligase E3C
UniProt Synonym Protein Names
HectH2
Protein Family
Ubiquitin-protein ligase
UniProt Gene Name
UBE3C
UniProt Synonym Gene Names
KIAA0010; KIAA10
UniProt Entry Name
UBE3C_HUMAN
NCBI Protein Information
ubiquitin-protein ligase E3C

UniProt Comments for UBE3C

UBE3C: E3 ubiquitin-protein ligase that accepts ubiquitin from the E2 ubiquitin-conjugating enzyme UBE2D1 in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Can assemble unanchored poly-ubiquitin chains in either 'Lys-29'- or 'Lys-48'-linked polyubiquitin chains. Has preference for 'Lys-48' linkages. It can target itself for ubiquitination in vitro and may promote its own degradation in vivo. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: EC 6.3.2.-; Ubiquitin ligase; Ligase; EC 6.3.2.19; Ubiquitin conjugating system

Chromosomal Location of Human Ortholog: 7q36.3

Cellular Component: cytoplasm; intracellular; nucleus

Molecular Function: protein binding; ubiquitin-protein ligase activity

Biological Process: protein polyubiquitination; protein ubiquitination during ubiquitin-dependent protein catabolic process
Show more

Research Articles on UBE3C

1. data reveal that high UBE3C expression contributes to glioma progression by ubiquitination and degradation of ANXA7, and thus presents a novel and promising target for glioma therapy.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with UBE3C cdna clone

 Products by Pathway  Pathway Diagram
 Adaptive Immune System Pathway antibodies  Adaptive Immune System Pathway Diagram
 Antigen Processing: Ubiquitination & Proteasome Degradation Pathway antibodies  Antigen Processing: Ubiquitination & Proteasome Degradation Pathway Diagram
 Class I MHC Mediated Antigen Processing & Presentation Pathway antibodies  Class I MHC Mediated Antigen Processing & Presentation Pathway Diagram
 Immune System Pathway antibodies  Immune System Pathway Diagram
 Ubiquitin Mediated Proteolysis Pathway antibodies  Ubiquitin Mediated Proteolysis Pathway Diagram
 Ubiquitin Mediated Proteolysis Pathway antibodies  Ubiquitin Mediated Proteolysis Pathway Diagram

Diseases associated with UBE3C cdna clone

 Disease Name  Pubmed Publications
 Inflammation Antibodies  >1 publications with UBE3C and Inflammation

Organs/Tissues associated with UBE3C cdna clone

 Organ/Tissue Name  Pubmed Publications
 Spinal Cord Antibodies  >1 publications with UBE3C and Spinal Cord
 Bone Antibodies  >1 publications with UBE3C and Bone
 Muscle Antibodies  >1 publications with UBE3C and Muscle
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000