Human USP1 cDNA Clone Expression Plasmid – Cat# MBS1277481

USP1 cDNA Clone – Ubiquitin Specific Peptidase 1 (Human)

Name: USP1 cDNA Clone; Ubiquitin Specific Peptidase 1; Human; MyBioSource
Brand: MyBioSource
SKU: MBS1277481
Price: 885 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1277481

MBS1277481 is a cDNA clone targeting USP1. More details

$885 / 0.01 mg Plasmid + 0.2 mL Glycerol-Stock +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

USP1, cDNA Clone

Full Product Name

USP1 cDNA Clone

Product Gene Name

USP1 cdna clone

Sequence

atgcctggtg tcatacctag tgaaagtaat ggactttcaa gaggtagccc ttcaaagaaa aacagacttt ccttaaagtt ttttcagaaa aaggaaacta agagagcttt ggatttcaca gattctcaag aaaatgaaga aaaagcttct gaatatagag catctgaaat tgatcaagtt gttcctgcag cacagtcttc acctataaac tgtgagaaga gagaaaactt gttaccattt gtgggactga ataatctcgg caatacttgc tatcttaata gtatacttca ggtattatat ttttgtcccg gttttaaatc tggagtaaag cacttattta atattatttc aaggaagaaa gaagctctaa aggatgaagc caatcaaaaa gacaagggaa attgcaaaga agattctttg gcaagttatg aattgatatg cagtttacag tccttaatca tttcggttga acagctccag gctagttttc tcttaaatcc agagaaatat actgatgaac ttgccactca gccaaggcga ctgcttaaca cactgaggga actcaaccct atgtatgaag gatatctaca gcatgatgca caggaagtat tacaatgtat tttgggaaac attcaagaaa catgccaact cctaaaaaaa gaagaagtaa aaaatgtggc agaattacct actaaggtag aagaaatacc tcatccgaaa gaggaaatga atggtattaa cagcatagag atggacagta tgaggcattc tgaagacttt aaagagaaac tcccaaaagg aaatgggaaa agaaaaagtg acactgaatt tggtaacatg aagaaaaaag ttaaattatc caaggaacac cagtcattgg aagagaacca gagacaaact agatcaaaaa gaaaagctac aagtgataca ttagagagtc ctcctaaaat aattcccaag tatatttctg aaaatgagag tccaagaccc tcacaaaaga aatcaagagt taaaataaat tggttaaagt ctgcaactaa gcaacccagc attctttcta aattttgtag tctgggaaaa ataacaacaa accaaggagt caaaggacaa tctaaagaaa atgaatgtga tcctgaagag gacttgggga agtgtgaaag tgataacaca actaatggtt gtggacttga atctccagga aatactgtta cacctgtaaa tgttaatgaa gttaaaccca taaacaaagg tgaagaacaa attggttttg agctagtgga gaaattattt caaggtcagc tggtattaag gacgcgttgc ttggaatgtg aaagtttaac agaaagaaga gaagattttc aagacatcag tgtgccagta caagaagatg agctttccaa agtagaggag agttctgaaa tttctccaga gccaaaaaca gaaatgaaga ccctgagatg ggcaatttca caatttgctt cagtagaaag gattgtagga gaagataaat atttctgtga aaactgccat cattatactg aagctgaacg aagtcttttg tttgacaaaa tgcctgaagt tataactatt catttgaagt gctttgctgc tagtggtttg gagtttgatt gttatggtgg tggactttcc aagatcaaca ctcctttatt gacacctctt aaattgtcac tagaagaatg gagcacaaag ccaactaacg acagctatgg attatttgcg gttgtgatgc atagtggcat tacaattagt agtgggcatt acactgcttc tgttaaagtc actgacctta acagtttaga actagataaa ggaaattttg tggttgacca aatgtgtgaa ataggtaagc cagaaccatt gaatgaggag gaagcaaggg gtgtggttga gaattataat gatgaagaag tgtcaattag agttggtgga aatacacagc caagtaaagt tttgaacaaa aaaaatgtag aagctattgg acttcttgga ggacaaaaga gcaaagcaga ttatgagcta tacaacaaag cctctaatcc tgataaggtt gctagtacag cgtttgctga aaatagaaat tctgagacta gtgatactac tgggacccat gaatctgata gaaacaagga atccagtgac caaacaggca ttaatattag tggatttgag aacaaaattt catacgtagt gcaaagctta aaggagtatg aggggaagtg gttgcttttt gatgattctg aagtcaaagt tactgaagag aaggactttc tgaattctct ttccccttct acatctccta cttctactcc ttacttgcta ttttataaga aattatag

Molecular Weight

88,207 Da

OMIM

603478

Vector

Please Inquire

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of USP1 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for USP1. It may not necessarily be applicable to this product.

NCBI GI #

29791615

NCBI GeneID

7398

NCBI Accession #

BC050525

UniProt Secondary Accession #

Q05BX7; Q59H66; Q9UFR0; Q9UNJ3; A0PJ95; D3DQ57

UniProt Related Accession #

O94782

NCBI Official Full Name

Homo sapiens ubiquitin specific peptidase 1, mRNA

NCBI Official Synonym Full Names

ubiquitin specific peptidase 1

NCBI Official Symbol

USP1

NCBI Official Synonym Symbols

UBP

UniProt Protein Name

Ubiquitin carboxyl-terminal hydrolase 1

UniProt Synonym Protein Names

Deubiquitinating enzyme 1; hUBP; Ubiquitin thioesterase 1; Ubiquitin-specific-processing protease 1

Protein Family

Protein

UniProt Gene Name

USP1

UniProt Synonym Gene Names

hUBP

UniProt Entry Name

UBP1_HUMAN

NCBI Protein Information

ubiquitin carboxyl-terminal hydrolase 1

NCBI Summary for USP1

This gene encodes a member of the ubiquitin-specific processing (UBP) family of proteases that is a deubiquitinating enzyme (DUB) with His and Cys domains. This protein is located in the cytoplasm and cleaves the ubiquitin moiety from ubiquitin-fused precursors and ubiquitinylated proteins. The protein specifically deubiquitinates a protein in the Fanconi anemia (FA) DNA repair pathway. Alternate transcriptional splice variants have been characterized. [provided by RefSeq, Jul 2008]

UniProt Comments for USP1

USP1: Negative regulator of DNA damage repair which specifically deubiquitinates monoubiquitinated FANCD2. Also involved in PCNA-mediated translesion synthesis (TLS) by deubiquitinating monoubiquitinated PCNA. Has almost no deubiquitinating activity by itself and requires the interaction with WDR48 to have a high activity. Interacts with FANCD2 and PCNA. Interacts with WDR48. Down-regulated following DNA damage. Belongs to the peptidase C19 family.

Protein type: Ubiquitin conjugating system; Ubiquitin-specific protease; Protease; EC 3.4.19.12

Chromosomal Location of Human Ortholog: 1p31.3

Cellular Component: nucleoplasm; nucleus

Molecular Function: cysteine-type endopeptidase activity; protein binding; ubiquitin-specific protease activity

Biological Process: DNA damage response, detection of DNA damage; protein deubiquitination; regulation of DNA repair; response to UV

Research Articles on USP1

1. analysis of the function and regulation of the USP1-UAF1 complex

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with USP1 cdna clone

Products by Pathway	Pathway Diagram
DNA Repair Pathway antibodies	DNA Repair Pathway Diagram
Fanconi Anemia Pathway antibodies	Fanconi Anemia Pathway Diagram
Fanconi Anemia Pathway antibodies	Fanconi Anemia Pathway Diagram
Fanconi Anemia Pathway antibodies	Fanconi Anemia Pathway Diagram
Regulation Of The Fanconi Anemia Pathway antibodies	Regulation Of The Fanconi Anemia Pathway Diagram

Diseases associated with USP1 cdna clone

Disease Name	Pubmed Publications
Anemia Antibodies	>19 publications with USP1 and Anemia
Neoplasms Antibodies	>6 publications with USP1 and Neoplasms
Neoplasms, Experimental Antibodies	>1 publications with USP1 and Neoplasms, Experimental
Breast Neoplasms Antibodies	>1 publications with USP1 and Breast Neoplasms
Infertility, Female Antibodies	>1 publications with USP1 and Infertility, Female

Organs/Tissues associated with USP1 cdna clone

Organ/Tissue Name	Pubmed Publications
Bone Antibodies	>3 publications with USP1 and Bone
Skin Antibodies	>3 publications with USP1 and Skin
Bone Marrow Antibodies	>3 publications with USP1 and Bone Marrow
Blood Antibodies	>2 publications with USP1 and Blood
Lung Antibodies	>2 publications with USP1 and Lung
Ovary Antibodies	>1 publications with USP1 and Ovary
Placenta Antibodies	>1 publications with USP1 and Placenta
Kidney Antibodies	>1 publications with USP1 and Kidney
Embryonic Tissue Antibodies	>1 publications with USP1 and Embryonic Tissue