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VDAC3 cDNA Clone – Voltage-Dependent Anion Channel 3 (Human)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1278028

MBS1278028 is a cDNA clone targeting VDAC3. More details

$235 / 0.01 mg Plasmid + 0.2 mL Glycerol-Stock +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
VDAC3, cDNA Clone
Full Product Name
VDAC3 cDNA Clone
Product Gene Name
VDAC3 cdna clone
Sequence
atgtgtaaca caccaacgta ctgtgaccta ggaaaggctg ctaaggatgt cttcaacaaa ggatatggct ttggcatggt caagatagac ctgaaaacca agtcttgtag tggagtggaa ttttctactt ctggtcatgc ttacactgat acagggaaag catcaggcaa cctagaaacc aaatataagg tctgtaacta tggacttacc ttcacccaga aatggaacac agacaatact ctagggacag aaatctcttg ggagaataag ttggctgaag ggttgaaact gactcttgat accatatttg taccgaacac aggaaagaag agtgggaaat tgaaggcctc ctataaacgg gattgtttta gtgttggcag taatgttgat atagattttt ctggaccaac catctatggc tgggctgtgt tggccttcga agggtggctt gctggctatc agatgagttt tgacacagcc aaatccaaac tgtcacagaa taatttcgcc ctgggttaca aggctgcgga cttccagctg cacacacatg tgaacgatgg cactgaattt ggaggttcta tctaccagaa ggtgaatgag aagattgaaa catccataaa ccttgcttgg acagctggga gtaacaacac ccgttttggc attgctgcta agtacatgct ggattgtaga acttctctct ctgctaaagt aaataatgcc agcctgattg gactgggtta tactcagacc cttcgaccag gagtcaaatt gactttatca gctttaatcg atgggaagaa cttcagtgca ggaggtcaca aggttggctt gggatttgaa ctggaagctt aa
Molecular Weight
30,790 Da
OMIM
610029
Vector
pENTR223.1 or pUC
Clone Sequence Report
Provided with product shipment
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of VDAC3 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for VDAC3. It may not necessarily be applicable to this product.

NCBI GI #
34783949
NCBI GeneID
7419
NCBI Accession #
BC056870
UniProt Secondary Accession #
Q9UIS0
UniProt Related Accession #
Q9Y277
NCBI Official Full Name
Homo sapiens voltage-dependent anion channel 3, mRNA
NCBI Official Synonym Full Names
voltage dependent anion channel 3
NCBI Official Symbol
VDAC3
NCBI Official Synonym Symbols
VDAC-3; HD-VDAC3
UniProt Protein Name
Voltage-dependent anion-selective channel protein 3
UniProt Synonym Protein Names
Outer mitochondrial membrane protein porin 3
Protein Family
Mitochondrial outer membrane protein porin
UniProt Gene Name
VDAC3
UniProt Synonym Gene Names
VDAC-3; hVDAC3
UniProt Entry Name
VDAC3_HUMAN
NCBI Protein Information
voltage-dependent anion-selective channel protein 3

NCBI Summary for VDAC3

This gene encodes a voltage-dependent anion channel (VDAC), and belongs to the mitochondrial porin family. VDACs are small, integral membrane proteins that traverse the outer mitochondrial membrane and conduct ATP and other small metabolites. They are known to bind several kinases of intermediary metabolism, thought to be involved in translocation of adenine nucleotides, and are hypothesized to form part of the mitochondrial permeability transition pore, which results in the release of cytochrome c at the onset of apoptotic cell death. Alternatively transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Oct 2011]
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UniProt Comments for VDAC3

VDAC3: a protein of the eukaryotic mitochondrial porin family. Forms a voltage-dependent anion channel through the mitochondrial outer membrane that allows diffusion of small hydrophilic molecules. Two splice-variant isoforms have been described.

Protein type: Mitochondrial; Membrane protein, integral; Channel, misc.

Chromosomal Location of Human Ortholog: 8p11.2

Cellular Component: mitochondrion; nucleus

Molecular Function: voltage-gated anion channel activity

Biological Process: adenine transport
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Research Articles on VDAC3

1. The works available on VDAC cysteines support the notion that VDAC1, VDAC2, and VDAC3 proteins are paralogs with a similar pore-function and slightly different, but important, ancillary biological functions. (Review)

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with VDAC3 cdna clone

 Products by Pathway  Pathway Diagram
 Calcium Signaling Pathway antibodies  Calcium Signaling Pathway Diagram
 Calcium Signaling Pathway antibodies  Calcium Signaling Pathway Diagram
 HTLV-I Infection Pathway antibodies  HTLV-I Infection Pathway Diagram
 HTLV-I Infection Pathway antibodies  HTLV-I Infection Pathway Diagram
 Hepatitis B Pathway antibodies  Hepatitis B Pathway Diagram
 Huntington's Disease Pathway antibodies  Huntington's Disease Pathway Diagram
 Huntington's Disease Pathway antibodies  Huntington's Disease Pathway Diagram
 Parkinson's Disease Pathway antibodies  Parkinson's Disease Pathway Diagram
 Viral Carcinogenesis Pathway antibodies  Viral Carcinogenesis Pathway Diagram
 Viral Carcinogenesis Pathway antibodies  Viral Carcinogenesis Pathway Diagram

Diseases associated with VDAC3 cdna clone

 Disease Name  Pubmed Publications
 Death Antibodies  >12 publications with VDAC3 and Death
 Neoplasms Antibodies  >6 publications with VDAC3 and Neoplasms
 Carcinoma, Hepatocellular Antibodies  >4 publications with VDAC3 and Carcinoma, Hepatocellular
 Liver Diseases Antibodies  >3 publications with VDAC3 and Liver Diseases
 Liver Neoplasms Antibodies  >3 publications with VDAC3 and Liver Neoplasms
 Hypertension Antibodies  >1 publications with VDAC3 and Hypertension
 Drug Toxicity Antibodies  >1 publications with VDAC3 and Drug Toxicity
 Necrosis Antibodies  >1 publications with VDAC3 and Necrosis
 Edema Antibodies  >1 publications with VDAC3 and Edema
 Liver Neoplasms, Experimental Antibodies  >1 publications with VDAC3 and Liver Neoplasms, Experimental

Organs/Tissues associated with VDAC3 cdna clone

 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >8 publications with VDAC3 and Brain
 Muscle Antibodies  >7 publications with VDAC3 and Muscle
 Liver Antibodies  >5 publications with VDAC3 and Liver
 Heart Antibodies  >4 publications with VDAC3 and Heart
 Eye Antibodies  >4 publications with VDAC3 and Eye
 Embryonic Tissue Antibodies  >4 publications with VDAC3 and Embryonic Tissue
 Nerve Antibodies  >3 publications with VDAC3 and Nerve
 Testis Antibodies  >2 publications with VDAC3 and Testis
 Placenta Antibodies  >1 publications with VDAC3 and Placenta
 Uterus Antibodies  >1 publications with VDAC3 and Uterus
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