Human VIM cDNA Clone Expression Plasmid – Cat# MBS1275586

VIM cDNA Clone – Vimentin (Human)

Name: VIM cDNA Clone; Vimentin; Human; MyBioSource
Brand: MyBioSource
SKU: MBS1275586
Price: 560 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1275586

MBS1275586 is a cDNA clone targeting VIM. More details

$560 / 0.01 mg Plasmid + 0.2 mL Glycerol-Stock +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

VIM, cDNA Clone

Full Product Name

VIM cDNA Clone

Product Gene Name

VIM cdna clone

Sequence

atgtccacca ggtccgtgtc ctcgtcctcc taccgcagga tgttcggcgg cccgggcacc gcgagccggc cgagctccag ccggagctac gtgactacgt ccacccgcac ctacagcctg ggcagcgcgc tgcgccccag caccagccgc agcctctacg cctcgtcccc gggcggcgtg tatgccacgc gctcctctgc cgtgcgcctg cggagcagcg tgcccggggt gcggctcctg caggactcgg tggacttctc gctggccgac gccatcaaca ccgagttcaa gaacacccgc accaacgaga aggtggagct gcaggagctg aatgaccgct tcgccaacta catcgacaag gtgcgcttcc tggagcagca gaataagatc ctgctggccg agctcgagca gctcaagggc caaggcaagt cgcgcctggg ggacctctac gaggaggaga tgcgggagct gcgccggcag gtggaccagc taaccaacga caaagcccgc gtcgaggtgg agcgcgacaa cctggccgag gacatcatgc gcctccggga gaaattgcag gaggagatgc ttcagagaga ggaagccgaa aacaccctgc aatctttcag acaggatgtt gacaatgcgt ctctggcacg tcttgacctt gaacgcaaag tggaatcttt gcaagaagag attgcctttt tgaagaaact ccacgaagag gaaatccagg agctgcaggc tcagattcag gaacagcatg tccaaatcga tgtggatgtt tccaagcctg acctcacggc tgccctgcgt gacgtacgtc agcaatatga aagtgtggct gccaagaacc tgcaggaggc agaagaatgg tacaaatcca agtttgctga cctctctgag gctgccaacc ggaacaatga cgccctgcgc caggcaaagc aggagtccac tgagtaccgg agacaggtgc agtccctcac ctgtgaagtg gatgccctta aaggaaccaa tgagtccctg gaacgccaga tgcgtgaaat ggaagagaac tttgccgttg aagctgctaa ctaccaagac actattggcc gcctgcagga tgagattcag aatatgaagg aggaaatggc tcgtcacctt cgtgaatacc aagacctgct caatgttaag atggcccttg acattgagat tgccacctac aggaagctgc tggaaggcga ggagagcagg atttctctgc ctcttccaaa cttttcctcc ctgaacctga gggaaactaa tctggattca ctccctctgg ttgataccca ctcaaaaagg acacttctga ttaagacggt tgaaactaga gatggacagg ttatcaacga aacttctcag catcacgatg accttgaata a

Molecular Weight

53,652 Da

OMIM

116300

Vector

Please Inquire

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of VIM cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for VIM. It may not necessarily be applicable to this product.

NCBI GI #

13111800

NCBI GeneID

7431

NCBI Accession #

BC000163

UniProt Secondary Accession #

Q15867; Q15868; Q15869; Q548L2; Q6LER9; Q8N850; Q96ML2; Q9NTM3; B0YJC2; D3DRU4

UniProt Related Accession #

P08670

NCBI Official Full Name

Homo sapiens vimentin, mRNA

NCBI Official Synonym Full Names

vimentin

NCBI Official Symbol

VIM

NCBI Official Synonym Symbols

HEL113; CTRCT30

UniProt Protein Name

Vimentin

Protein Family

Vimentin

UniProt Gene Name

VIM

UniProt Entry Name

VIME_HUMAN

NCBI Protein Information

vimentin

NCBI Summary for VIM

This gene encodes a member of the intermediate filament family. Intermediate filamentents, along with microtubules and actin microfilaments, make up the cytoskeleton. The protein encoded by this gene is responsible for maintaining cell shape, integrity of the cytoplasm, and stabilizing cytoskeletal interactions. It is also involved in the immune response, and controls the transport of low-density lipoprotein (LDL)-derived cholesterol from a lysosome to the site of esterification. It functions as an organizer of a number of critical proteins involved in attachment, migration, and cell signaling. Mutations in this gene causes a dominant, pulverulent cataract.[provided by RefSeq, Jun 2009]

UniProt Comments for VIM

Vimentin: an intermediate filament protein. Intermediate filament proteins are expressed in a tissue-specific manner. Desmin is the subunit specific for muscle and vimentin the subunit specific for mesenchymal tissue.

Protein type: Cytoskeletal; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 10p13

Cellular Component: cytoplasm; cytoskeleton; cytosol; extracellular matrix; focal adhesion; intermediate filament; intermediate filament cytoskeleton; peroxisome; plasma membrane

Molecular Function: double-stranded RNA binding; glycoprotein binding; identical protein binding; protein binding; protein C-terminus binding; structural constituent of cytoskeleton

Biological Process: cell motility; muscle filament sliding

Disease: Cataract 30

Research Articles on VIM

1. HtrA2 under stress conditions induces vimentin cleavage in wild-type and SH-SY5Y cells transfected with APP with the Alzheimer disease-associated Swedish mutation. Interplay between Omi/HtrA2 and vimentin affects mitochondrial distribution in neurons.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with VIM cdna clone

Products by Pathway	Pathway Diagram
Alpha6-Beta4 Integrin Signaling Pathway antibodies	Alpha6-Beta4 Integrin Signaling Pathway Diagram
Apoptosis Pathway antibodies	Apoptosis Pathway Diagram
Apoptotic Cleavage Of Cellular Proteins Pathway antibodies	Apoptotic Cleavage Of Cellular Proteins Pathway Diagram
Apoptotic Execution Phase Pathway antibodies	Apoptotic Execution Phase Pathway Diagram
Aurora B Signaling Pathway antibodies	Aurora B Signaling Pathway Diagram
Caspase Cascade In Apoptosis Pathway antibodies	Caspase Cascade In Apoptosis Pathway Diagram
Caspase-mediated Cleavage Of Cytoskeletal Proteins Pathway antibodies	Caspase-mediated Cleavage Of Cytoskeletal Proteins Pathway Diagram
Epstein-Barr Virus Infection Pathway antibodies	Epstein-Barr Virus Infection Pathway Diagram
Epstein-Barr Virus Infection Pathway antibodies	Epstein-Barr Virus Infection Pathway Diagram
Muscle Contraction Pathway antibodies	Muscle Contraction Pathway Diagram

Diseases associated with VIM cdna clone

Disease Name	Pubmed Publications
Nervous System Diseases Antibodies	>383 publications with VIM and Nervous System Diseases
Neoplasms Antibodies	>283 publications with VIM and Neoplasms
Brain Diseases Antibodies	>246 publications with VIM and Brain Diseases
Neurodegenerative Diseases Antibodies	>166 publications with VIM and Neurodegenerative Diseases
Inflammation Antibodies	>46 publications with VIM and Inflammation
Kidney Diseases Antibodies	>37 publications with VIM and Kidney Diseases
Hemorrhage Antibodies	>32 publications with VIM and Hemorrhage
Disease Models, Animal Antibodies	>32 publications with VIM and Disease Models, Animal
Pain Antibodies	>31 publications with VIM and Pain
Liver Diseases Antibodies	>29 publications with VIM and Liver Diseases

Organs/Tissues associated with VIM cdna clone

Organ/Tissue Name	Pubmed Publications
Brain Antibodies	>461 publications with VIM and Brain
Blood Antibodies	>187 publications with VIM and Blood
Muscle Antibodies	>101 publications with VIM and Muscle
Nerve Antibodies	>79 publications with VIM and Nerve
Bone Antibodies	>69 publications with VIM and Bone
Kidney Antibodies	>52 publications with VIM and Kidney
Liver Antibodies	>51 publications with VIM and Liver
Bone Marrow Antibodies	>46 publications with VIM and Bone Marrow
Eye Antibodies	>38 publications with VIM and Eye
Vascular Antibodies	>35 publications with VIM and Vascular