Human VPS52 cDNA Clone Expression Plasmid – Cat# MBS1276292

VPS52 cDNA Clone – Vacuolar Protein Sorting 52 Homolog (S. Cerevisiae) (Human)

Name: VPS52 cDNA Clone; Human; MyBioSource
Brand: MyBioSource
SKU: MBS1276292
Price: 820 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1276292

MBS1276292 is a cDNA clone targeting VPS52. More details

$820 / 0.01 mg Plasmid + 0.2 mL Glycerol-Stock +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

VPS52, cDNA Clone

Full Product Name

VPS52 cDNA Clone

Product Gene Name

VPS52 cdna clone

Sequence

atggccgccg ctgcgaccat ggcggctgcg gcccgggaac tggtgttgcg ggctgggacc tcagatatgg aggaggaaga gggcccgctg gcgggtggtc ctgggctcca ggaaccactg caacttgggg agttggatat cacttctgat gaattcatcc tggatgaagt ggatgttcac attcaggcaa atctggagga tgagttagta aaggaagctc ttaaaacggg tgtagatctc cgtcactatt caaagcaagt tgagctggag ctacagcaga ttgaacagaa atccattcgg gattatattc aagagagtga gaatatagca tctctacaca accagatcac agcctgtgat gctgtcctgg agcgaatgga gcagatgttg ggagcttttc agagtgacct cagctccatc agctctgaga tccggacact gcaggaacag tcaggagcca tgaacattcg acttcgaaat cgccaggcag ttcgggggaa acttggggag cttgttgatg gtctggtggt gccttctgct ctggtcacgg caattctgga ggctccagtg acagagccca ggttcttgga gcagctacag gagctggatg ccaaggcagc cgcagtcaga gagcaggaag ctagaggcac agcagcctgc gcagatgtca gaggcgtgct cgatcggctc cgggtcaagg cagtgacgaa gatccgagag tttatcctcc agaagattta ttccttcagg aaacccatga ccaactatca gatcccccag acggccctgc tgaagtacag gttcttctat cagtttctgc tgggcaatga acgagcaaca gcaaaggaga tcagggatga atatgtggag acgctgagca agatttacct gtcttactac cgctcttacc tggggcggct catgaaggtg cagtatgagg aagtcgctga gaaagatgat ctaatgggtg tggaagatac agcaaagaaa ggattcttct caaagccatc gctccgcagc aggaacacca ttttcaccct aggaacccgc ggctctgtca tctcccccac tgaacttgag gcccccatcc tggtgcctca cacagcgcag cgcggagagc agaggtatcc atttgaggcc ctcttccgca gccagcacta cgccctccta gacaattcct gccgcgaata ccttttcatc tgtgaatttt ttgttgtgtc tggcccagct gcacacgacc tgttccatgc tgtcatgggc cgtacactca gcatgaccct gaaacacctg gattcttatc tagctgactg ctacgatgcc attgctgttt ttctctgtat ccacattgtt ctccggttcc gtaacattgc agcaaagagg gatgttcctg ccctggacag gtactgggaa caggtgcttg ccttgctatg gccacggttt gaactgatcc tggagatgaa tgttcagagc gtccgaagca ctgaccccca gcgcctaggg gggttggata ctcggcccca ctatatcaca cgccgctatg cagagttctc ctccgctctt gtcagtatca accagacaat tcctaatgaa cggaccatgc aattgctggg acagctgcag gtggaggtgg agaattttgt cctccgagtg gcagctgagt tctcctcaag gaaggagcag cttgtgtttc tgatcaacaa ctatgacatg atgctgggtg tgctgatgga gcgggctgca gatgacagca aagaggttga gagcttccag cagctgctca atgctcggac acaggaattc attgaagagt tgctgtctcc cccttttggg ggtttagtgg catttgtgaa ggaggctgag gctttgattg agcgtggaca ggctgagcga cttcgagggg aagaagcccg ggtaactcag ctgatccgtg gctttggtag ttcctggaaa tcatcagtgg aatctctgag tcaggatgta atgcggagtt tcaccaactt cagaaatggc accagtatca ttcagggagc gctgacccag ctgatccagc tctatcatcg cttccaccgg gtgctgtccc agccgcagct ccgagccctc cctgcccggg ctgagctcat caacattcac caccttatgg tggagctcaa gaagcataag cccaacttct ga

Molecular Weight

68,496 Da

OMIM

603443

Vector

Please Inquire

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of VPS52 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for VPS52. It may not necessarily be applicable to this product.

NCBI GI #

21594272

NCBI GeneID

6293

NCBI Accession #

BC032108

UniProt Secondary Accession #

Q53GR4; Q5JPA0; Q5SQW1; Q8IUN6; Q9NPT5; A2BF38; B0UZZ4; B4DNI9

UniProt Related Accession #

Q8N1B4

NCBI Official Full Name

Homo sapiens vacuolar protein sorting 52 homolog (S. cerevisiae), mRNA

NCBI Official Synonym Full Names

VPS52, GARP complex subunit

NCBI Official Symbol

VPS52

NCBI Official Synonym Symbols

ARE1; SAC2; SACM2L; dJ1033B10.5

UniProt Protein Name

Vacuolar protein sorting-associated protein 52 homolog

UniProt Synonym Protein Names

SAC2 suppressor of actin mutations 2-like protein

Protein Family

Vacuolar protein sorting-associated protein

UniProt Gene Name

VPS52

UniProt Synonym Gene Names

SACM2L

UniProt Entry Name

VPS52_HUMAN

NCBI Protein Information

vacuolar protein sorting-associated protein 52 homolog

NCBI Summary for VPS52

This gene encodes a protein that is similar to the yeast suppressor of actin mutations 2 gene. The yeast protein forms a subunit of the tetrameric Golgi-associated retrograde protein complex that is involved in vesicle trafficking from from both early and late endosomes, back to the trans-Golgi network. This gene is located on chromosome 6 in a head-to-head orientation with the gene encoding ribosomal protein S18. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]

UniProt Comments for VPS52

VPS52: May be involved in retrograde transport of early and late endosomes to the late Golgi. The GARP complex is required for the maintenance of the cycling of mannose 6-phosphate receptors between the TGN and endosomes, this cycling is necessary for proper lysosomal sorting of acid hydrolases such as CTSD. Belongs to the VPS52 family.

Chromosomal Location of Human Ortholog: 6p21.3

Cellular Component: Golgi apparatus; membrane; perinuclear region of cytoplasm; recycling endosome; trans-Golgi network membrane

Molecular Function: protein binding; syntaxin binding

Biological Process: endocytic recycling; lysosomal transport

Research Articles on VPS52

1. our data indicate that cisplatin resistance in HOCCs is partially attributable to their high expression of p62, which plays an important role in preventing ROS stress-induced apoptosis by regulating the Keap1-Nrf2-ARE signaling pathway.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Diseases associated with VPS52 cdna clone

Disease Name	Pubmed Publications
Inflammation Antibodies	>3 publications with VPS52 and Inflammation
Drug Toxicity Antibodies	>2 publications with VPS52 and Drug Toxicity
Nervous System Diseases Antibodies	>2 publications with VPS52 and Nervous System Diseases
Brain Diseases Antibodies	>1 publications with VPS52 and Brain Diseases
Gastrointestinal Diseases Antibodies	>1 publications with VPS52 and Gastrointestinal Diseases
Weight Loss Antibodies	>1 publications with VPS52 and Weight Loss
Seizures Antibodies	>1 publications with VPS52 and Seizures
Drug-Induced Liver Injury Antibodies	>1 publications with VPS52 and Drug-Induced Liver Injury

Organs/Tissues associated with VPS52 cdna clone

Organ/Tissue Name	Pubmed Publications
Liver Antibodies	>2 publications with VPS52 and Liver
Brain Antibodies	>2 publications with VPS52 and Brain
Embryonic Tissue Antibodies	>1 publications with VPS52 and Embryonic Tissue
Blood Antibodies	>1 publications with VPS52 and Blood
Connective Tissue Antibodies	>1 publications with VPS52 and Connective Tissue
Skin Antibodies	>1 publications with VPS52 and Skin
Testis Antibodies	>1 publications with VPS52 and Testis