Human ZFYVE16 cDNA Clone Expression Plasmid – Cat# MBS1276251

ZFYVE16 cDNA Clone – Zinc Finger, FYVE Domain Containing 16 (Human)

Name: ZFYVE16 cDNA Clone; Human; MyBioSource
Brand: MyBioSource
SKU: MBS1276251
Price: 1550 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1276251

MBS1276251 is a cDNA clone targeting ZFYVE16. More details

$1550 / 0.01 mg Plasmid + 0.2 mL Glycerol-Stock +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

ZFYVE16, cDNA Clone

Full Product Name

ZFYVE16 cDNA Clone

Product Gene Name

ZFYVE16 cdna clone

Sequence

atggacagtt attttaaagc agctgtcagt gacttggaca aactccttga tgattttgaa cagaacccag atgaacaaga ttatctccaa gatgtacaaa atgcatatga ttctaaccac tgctcagttt cttcagagtt ggcttcctca cagcgaactt cattgctccc aaaagaccaa gagtgcgtta atagttgtgc ctcatcagaa acaagctatg gaacaaatga gagttccctg aatgaaaaaa cactcaaggg acttacttct atacaaaatg aaaaaaatgt aacaggactt gatcttcttt cttctgtgga tggtggtact tcagatgaaa tccagccgtt atatatggga cgatgtagta aacctatctg tgatctgata agtgacatgg gtaacttagt tcatgcaacc aatagtgaag aagatattaa aaaattattg ccagatgatt ttaagtctaa tgcagattcc ttgattggat tggatttatc ttcagtgtca gatactccct gtgtttcttc aacagaccat gatagtgata ctgtcagaga acaacagaat gataccagtt ctgaattaca aaatagagaa atcggaggaa tcaaagaatt gggtataaaa gtagatacaa cactttcaga ttcctataat tacagtggaa cagaaaattt aaaagataaa aagatcttta atcagttaga atcaattgtt gattttaaca tgtcatctgc tttgactcga caaagttcca aaatgtttca tgccaaagac aagctacaac acaagagcca gccatgtgga ttactaaaag atgttggctt agtaaaagag gaagtagatg tggcagtcat aactgccgca gaatgtttaa aagaagaggg caagacaagt gctttgacct gcagccttcc gaaaaatgaa gatttatgct taaatgattc aaattcaaga gatgaaaatt tcaaattacc tgacttttcc tttcaggaag ataagactgt tataaaacaa tctgcacaag aagactcaaa aagtttagac cttaaggata atgatgtaat ccaagattcc tcttcagctt tacatgtttc cagtaaagat gtgccgtcct cattgtcctg tcttcctgcg tctgggtcta tgtgtggatc attaattgaa agtaaagcac ggggtgattt tttacctcag catgaacata aagataatat acaagatgca gtgactatac atgaagaaat acagaacagt gttgttctag gtggggaacc attcaaagag aatgatcttt tgaaacagga aaaatgtaaa agcatactcc ttcagtcatt aattgaaggg atggaagaca gaaagataga tcctgaccag acagtaatca gagctgagtc tttggatggt ggtgacacca gttctacagt tgtagaatct caagaggggc tttctggcac tcatgtccca gagtcttctg attgttgtga aggttttatt aatacttttt caagcaatga tatggatggg caagacttag attactttaa tattgatgaa ggcgcaaaaa gtggcccact aattagtgat gctgaacttg atgcctttct gacagaacag tatcttcaga ccactaacat aaagtctttt gaagaaaatg taaatgactc taaatcgcaa atgaatcaga tagatatgaa aggcttagat gatggaaaca tcaataatat atatttcaat gcagaagcag gagctattgg ggaaagtcat ggtattaata taatttgtga aacagttgat aaacaaaata caatagaaaa tggcctttct ttaggagaaa aaagcactat tccagttcaa caagggttac ctaccagtaa gtctgagatt acaaatcaat tatcagtctc tgatattaac agtcaatctg ttggaggggc cagacctaag caattgttta gccttccatc aagaacaagg agttcaaagg acctgaataa gccagatgtt ccagatacaa tagaaagtga acccagcaca gcagataccg ttgttccaat cacttgtgct atagattcta cagctgatcc acaggttagc ttcaactcta attacattga tatagaaagt aattctgaag gtggatctag tttcgtaact gcaaatgaag attctgtacc tgaaaacact tgcaaagaag gcttggtttt gggccagaaa cagcctactt gggttcctga ttcagaagct ccaaactgta tgaactgcca agtcaaattt acttttacca aacggcgaca ccattgccga gcatgtggga aagtattttg tggtgtctgt tgtaatagga agtgtaaact gcaatatcta gaaaaggaag caagagtatg tgtagtctgc tatgaaacta ttagtaaagc tcaggcattt gaaaggatga tgagtccaac tggttctaat cttaagtcta atcattctga tgaatgtact actgtccagc ctcctcagga gaaccaaaca tccagtatac cttcaccagc aactttgcca gtctcagcac ttaaacaacc aggtgttgaa ggactatgtt ccaaagaaca gaagagagta tggtttgcag atggtatatt gcccaatggt gaagttgcag atacaacaaa attatcatct ggaagtaaaa gatgttctga agactttagt cctctctcac ctgatgtgcc tatgacagta aacacagtgg atcattccca ttctactaca gtggaaaagc caaacaatga gacaggagat attacaagaa atgagataat tcagagtcct atttctcagg ttccatcagt ggaaaaattg tctatgaaca caggaaatga ggggttacct acttctggtt catttacact agatgatgat gtttttgcag aaactgaaga accatctagt cctactggtg tcttagttaa cagcaattta cctattgcta gtatttcaga ttataggtta ctgtgtgata ttaacaagta tgtctgcaat aagattagtc ttctacctaa tgatgaggac agtttgcccc cacttctggt tgcatctgga gaaaagggat cagtgcctgt agtagaagaa catccatctc atgagcagat cattttgctt cttgaaggtg aaggctttca tcctgttaca tttgtcctaa atgctaatct actcgtgaat gtcaaattca tattttattc ctcagacaaa tattggtact tttcaaccaa tggattgcat ggcttgggac aggcagaaat tattattcta ttgttatgtt tgccaaatga agatactatt cctaaggaca tcttcagact atttatcacc atatataagg atgctctaaa aggaaaatac atagaaaact tggacaatat tacctttact gagagttttc tcagtagcaa ggatcacgga ggattcctgt ttattacacc tacttttcag aaacttgatg atctctcatt accaagtaat ccttttcttt gtggaattct tatccagaag cttgagattc cctgggcaaa ggtttttcct atgcgtttaa tgttgagatt gggtgcagaa tataaaggta agttttag

Molecular Weight

88,377 Da

OMIM

608880

Vector

pUC

Clone Sequence Report

Provided with product shipment

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of ZFYVE16 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for ZFYVE16. It may not necessarily be applicable to this product.

NCBI GI #

21619001

NCBI GeneID

9765

NCBI Accession #

BC032227

UniProt Secondary Accession #

O15023; Q5H9U2; Q7LAU7; Q86T69; Q8N5L3; Q8NEK3

UniProt Related Accession #

Q7Z3T8

NCBI Official Full Name

Homo sapiens zinc finger, FYVE domain containing 16, mRNA

NCBI Official Synonym Full Names

zinc finger FYVE-type containing 16

NCBI Official Symbol

ZFYVE16

NCBI Official Synonym Symbols

PPP1R69

UniProt Protein Name

Zinc finger FYVE domain-containing protein 16

UniProt Synonym Protein Names

Endofin; Endosome-associated FYVE domain protein

Protein Family

Zinc finger FYVE domain-containing protein

UniProt Gene Name

ZFYVE16

UniProt Synonym Gene Names

KIAA0305

UniProt Entry Name

ZFY16_HUMAN

NCBI Protein Information

zinc finger FYVE domain-containing protein 16

NCBI Summary for ZFYVE16

This gene encodes an endosomal protein that belongs to the FYVE zinc finger family of proteins. The encoded protein is thought to regulate membrane trafficking in the endosome. This protein functions as a scaffold protein in the transforming growth factor-beta signaling pathway and is involved in positive and negative feedback regulation of the bone morphogenetic protein signaling pathway. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]

UniProt Comments for ZFYVE16

endofin: May be involved in regulating membrane trafficking in the endosomal pathway. Overexpression induces endosome aggregation. Required to target TOM1 to endosomes. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Lipid-binding

Chromosomal Location of Human Ortholog: 5q14

Cellular Component: cytoplasm; early endosome; early endosome membrane; intracellular membrane-bound organelle

Molecular Function: phosphatidylinositol binding; phosphatidylinositol-3,4,5-triphosphate binding; protein binding; protein transporter activity

Biological Process: BMP signaling pathway; endosome transport; protein targeting to lysosome; regulation of endocytosis

Research Articles on ZFYVE16

1. Disruption of proper localization to the endosomes and the Y515 phosphorylation of Endofin enhanced MAPK activation suggesting that Endofin negatively modulates EGFR signaling following receptor endocytosis.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with ZFYVE16 cdna clone

Products by Pathway	Pathway Diagram
BMP Receptor Signaling Pathway antibodies	BMP Receptor Signaling Pathway Diagram
Endocytosis Pathway antibodies	Endocytosis Pathway Diagram
Endocytosis Pathway antibodies	Endocytosis Pathway Diagram
Signal Transduction Pathway antibodies	Signal Transduction Pathway Diagram
Signaling By BMP Pathway antibodies	Signaling By BMP Pathway Diagram
TGF-beta Receptor Signaling Pathway antibodies	TGF-beta Receptor Signaling Pathway Diagram
TGF-beta Signaling Pathway antibodies	TGF-beta Signaling Pathway Diagram
TGF-beta Signaling Pathway antibodies	TGF-beta Signaling Pathway Diagram

Diseases associated with ZFYVE16 cdna clone

Disease Name	Pubmed Publications
Neoplasms Antibodies	>4 publications with ZFYVE16 and Neoplasms
Cardiovascular Diseases Antibodies	>1 publications with ZFYVE16 and Cardiovascular Diseases

Organs/Tissues associated with ZFYVE16 cdna clone

Organ/Tissue Name	Pubmed Publications
Brain Antibodies	>2 publications with ZFYVE16 and Brain
Eye Antibodies	>1 publications with ZFYVE16 and Eye