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Cr2 elisa kit :: Mouse Complement receptor type 2 ELISA Kit

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Catalog # MBS289840
Unit / Price
  48-Strip-Wells  /  $355 +1 FREE 8GB USB
  96-Strip-Wells  /  $475 +1 FREE 8GB USB
  5x96-Strip-Wells  /  $2,030 +2 FREE 8GB USB
  10x96-Strip-Wells  /  $3,700 +4 FREE 8GB USB
Cr2 elisa kit
Product Name

Complement receptor type 2 (Cr2), ELISA Kit

Popular Item
Also Known As

Mouse Complement receptor type 2 ELISA Kit

Product Synonym Names
Mus musculus; Cr2; Complement receptor type 2; Cr2; Complement C3d receptor; Cr2; CD21; CD21
Product Gene Name
Research Use Only
For Research Use Only. Not for use in diagnostic procedures.
Request for Current Manual Insert
Sequence Length
1025
3D Structure
ModBase 3D Structure for P19070
Species Reactivity
Assay Type
Sandwich
Detection Range
0.78-50 ng/mL
Sensitivity
0.392 ng/mL
Intra-Assay CV
<=5.5%
Inter-Assay CV
<=7.9%
Recovery
98%
Preparation and Storage
For long term storage, please store the entire kit at -20 degree C.
Product Note
Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual.
Other Notes
Small volumes of Cr2 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
Searchable Terms forCr2purchase
MBS289840 is a ready-to-use microwell, strip plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Complement receptor type 2 (Cr2) ELISA Kit target analytes in biological samples. The concentration gradients of the kit standards or positive controls render a theoretical kit detection range in biological research samples containing Cr2. The ELISA analytical biochemical technique of the MBS289840 kit is based on Cr2 antibody-Cr2 antigen interactions (immunosorbency) and an HRP colorimetric detection system to detect Cr2 antigen targets in samples. The ELISA Kit is designed to detect native, not recombinant, Cr2. Appropriate sample types may include undiluted body fluids and/or tissue homogenates, secretions. Quality control assays assessing reproducibility identified the intra-assay CV (%) and inter-assay CV(%).
NCBI/Uniprot data below describe general gene information for Cr2. It may not necessarily be applicable to this product.
NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
Molecular Weight
112,995 Da
NCBI Official Full Name
Complement receptor type 2
NCBI Official Synonym Full Names
complement receptor 2
NCBI Official Symbol
NCBI Official Synonym Symbols
Cr1; C3DR; CD21; CD35; Cr-1; Cr-2
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NCBI Protein Information
complement receptor type 2
UniProt Protein Name
Complement receptor type 2
UniProt Synonym Protein Names
Complement C3d receptor; CD_antigen: CD21
Protein Family
UniProt Gene Name
UniProt Synonym Gene Names
UniProt Entry Name
CR2_MOUSE
UniProt Comments for Cr2
CR2: Receptor for complement C3Dd, for the Epstein-Barr virus on human B-cells and T-cells and for HNRPU. Participates in B lymphocytes activation. Genetic variations in CR2 are associated with susceptibility to systemic lupus erythematosus type 9 (SLEB9). Systemic lupus erythematosus (SLE) is a chronic autoimmune disease with a complex genetic basis. SLE is an inflammatory, and often febrile multisystemic disorder of connective tissue characterized principally by involvement of the skin, joints, kidneys, and serosal membranes. It is thought to represent a failure of the regulatory mechanisms of the autoimmune system. Defects in CR2 are the cause of immunodeficiency, common variable, type 7 (CVID7). A primary immunodeficiency characterized by antibody deficiency, hypogammaglobulinemia, recurrent bacterial infections and an inability to mount an antibody response to antigen. The defect results from a failure of B-cell differentiation and impaired secretion of immunoglobulins; the numbers of circulating B cells is usually in the normal range, but can be low. Belongs to the receptors of complement activation (RCA) family. 4 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Receptor, misc.

Cellular Component: external side of plasma membrane; integral to membrane; membrane; receptor complex

Molecular Function: complement binding; complement receptor activity; DNA binding; protein binding; protein homodimerization activity; receptor activity

Biological Process: B cell activation; B cell differentiation; B cell proliferation; complement activation, classical pathway; immune system process; innate immune response
Precautions
All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.
Disclaimer
While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.
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