Dynein IC1 Blocking Peptide – Cat# MBS9619554

Dynein IC1 Blocking Peptide – The purity is >90%,tested by HPLC and MS. Purity

Name: Dynein IC1 Blocking Peptide; The purity is >90%,tested by HPLC and MS. Purity; MyBioSource
Brand: MyBioSource
SKU: MBS9619554
Price: 460 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS9619554

Blocking peptides are peptides that bind specifically to the target antibody and block antibody binding. These peptide usually contains the epitope recognized by the antibody. Antibodies bound to the blocking peptide no longer bind to the epitope on the… More details

$460 / 1 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Dynein IC1 (DNAI1), Blocking Peptide

Full Product Name

Dynein IC1 Blocking Peptide

Product Gene Name

DNAI1 blocking peptide

Product Synonym Names

Axonemal dynein intermediate chain 1; Axonemal dynein intermediate chain 2; CILD 1; CILD1; Cytoplasmic dynein 1 intermediate chain 1; Cytoplasmic dynein 1 intermediate chain 2; Cytoplasmic dynein intermediate chain 1; Cytoplasmic dynein intermediate chain 2; DH IC 1; DH IC 2; DIC1; DNAI 1; DNAI 2; DNAI1; DNAI1_HUMAN; DNAI2; DNCI 2; DNCI1; DNCI2; DNCIC 1; DNCIC 2; DNCIC1; DNCIC2; DYNC1I1; DYNC1I2; Dynein axonemal intermediate chain 1; Dynein axonemal intermediate polypeptide 1; Dynein axonemal intermediate polypeptide 2; Dynein cytoplasmic intermediate polypeptide 1; Dynein cytoplasmic intermediate polypeptide 2; Dynein intermediate chain 1 axonemal; Dynein intermediate chain 1 cytosolic; Dynein intermediate chain 1, axonemal; Dynein intermediate chain 2 axonemal; Dynein intermediate chain 2 cytosolic; Dynein intermediate chain DNAI1; IC74; ICS; ICS1; Immotile cilia syndrome 1; MGC26204; PCD

Form/Format

Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 10 mg/ml.

Purity/Purification

The purity is >90%,tested by HPLC and MS.

Preparation and Storage

Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.

Antibody/Peptide Pairs

Dynein IC1 peptide (MBS9619554) is used for blocking the activity of Dynein IC1 antibody (MBS9602099)

Molecular Weight

79,283 Da

Chromosome Location

Chromosome: 9; NC_000009.11 (34458750..34520987). Location: 9p13.3

OMIM

phenotype 604366

Supply Chain Verification

Manufactured in a lab with traceable raw materials manufactured on site. Coordinated product portfolio of antibodies, pairs, conjugates, recombinant proteins, and immunoassay materials available, please inquire.

Notes

For phospho antibody, we provide phospho peptide (0.5mg) and non-phospho peptide (0.5mg)

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Applications Tested/Suitable for DNAI1 blocking peptide

Blocking/Control

Other Notes

Small volumes of DNAI1 blocking peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for DNAI1 purchase

MBS9619554 is a blocking peptide targeting DNAI1. Also known as Dynein IC1 Blocking Peptide.

Additional Details

NCBI/Uniprot data below describe general gene information for DNAI1. It may not necessarily be applicable to this product.

NCBI GI #

526479830

NCBI GeneID

27019

NCBI Accession #

NP_001268357.1

UniProt Primary Accession #

Q9UI46

UniProt Secondary Accession #

Q5T8G7; Q8NHQ7; Q9UEZ8; B7Z7U1

UniProt Related Accession #

Q9UI46

GenBank Nucleotide #

NM_001281428.1

NCBI Official Full Name

dynein intermediate chain 1, axonemal isoform 2

NCBI Official Synonym Full Names

dynein, axonemal, intermediate chain 1

NCBI Official Symbol

DNAI1

NCBI Official Synonym Symbols

PCD; DIC1; ICS1; CILD1

UniProt Protein Name

Dynein intermediate chain 1, axonemal

UniProt Synonym Protein Names

Axonemal dynein intermediate chain 1

Protein Family

Dynein

UniProt Gene Name

DNAI1

UniProt Entry Name

DNAI1_HUMAN

NCBI Protein Information

dynein intermediate chain 1, axonemal; immotile cilia syndrome 1; dynein, axonemal, intermediate polypeptide 1

NCBI Summary for DNAI1

This gene encodes a member of the dynein intermediate chain family. The encoded protein is part of the dynein complex in respiratory cilia. The inner- and outer-arm dyneins, which bridge between the doublet microtubules in axonemes, are the force-generating proteins responsible for the sliding movement in axonemes. The intermediate and light chains, thought to form the base of the dynein arm, help mediate attachment and may also participate in regulating dynein activity. Mutations in this gene result in abnormal ciliary ultrastructure and function associated with primary ciliary dyskinesia and Kartagener syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]

Research Articles on DNAI1

1. The worldwide involvement of DNAI1 mutations in PCD pathogenesis in families not preselected for ODA defects ranges from 7 to 10%.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with DNAI1 blocking peptide

Reference Product	PubMed Publications
DNAH5 blocking peptide	>20 publications with DNAI1 and DNAH5
DNAH11 blocking peptide	>10 publications with DNAI1 and DNAH11
DNAH9 blocking peptide	>2 publications with DNAI1 and DNAH9
C14orf104 blocking peptide	>1 publications with DNAI1 and C14orf104
RSPH4A blocking peptide	>1 publications with DNAI1 and RSPH4A
LRRC50 blocking peptide	>1 publications with DNAI1 and LRRC50

Pathways associated with DNAI1 blocking peptide

Products by Pathway	Pathway Diagram
Huntington's Disease Pathway antibodies	Huntington's Disease Pathway Diagram
Huntington's Disease Pathway antibodies	Huntington's Disease Pathway Diagram

Diseases associated with DNAI1 blocking peptide

Disease Name	Pubmed Publications
Heart Diseases Antibodies	>23 publications with DNAI1 and Heart Diseases
Kartagener Syndrome Antibodies	>22 publications with DNAI1 and Kartagener Syndrome
Fibrosis Antibodies	>3 publications with DNAI1 and Fibrosis
Inflammation Antibodies	>2 publications with DNAI1 and Inflammation

Organs/Tissues associated with DNAI1 blocking peptide

Organ/Tissue Name	Pubmed Publications
Lung Antibodies	>4 publications with DNAI1 and Lung
Testis Antibodies	>3 publications with DNAI1 and Testis
Trachea Antibodies	>2 publications with DNAI1 and Trachea
Eye Antibodies	>1 publications with DNAI1 and Eye
Pharynx Antibodies	>1 publications with DNAI1 and Pharynx