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AIM2 Antibody

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS852493

MBS852493 is an antibody targeting AIM2. Also known as AIM2 Antibody. Reactive in Human. More details

$380 / 0.1 mg +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
AIM2, Antibody
Full Product Name
AIM2 Antibody
Product Gene Name
Product Synonym Names
Interferon-inducible protein AIM2; Absent in melanoma 2; AIM2
Species Reactivity
Human
Form/Format
In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Specificity
AIM2 antibody detects endogenous levels of total AIM2 protein.
Preparation and Storage
Store at-20 degree C for 1 year.
Molecular Weight
38,954 Da
OMIM
604578
3D Structure
ModBase 3D Structure for O14862
Immunogen
The antiserum was produced against synthesized peptide derived from internal of human AIM2.
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-AIM2 antibody
Western Blot (WB), ELISA (EIA)
Application Notes for anti-AIM2 antibody
WB: 1:500~1:1000
ELISA: 1:40000

Western Blot (WB) of anti-AIM2 antibody

Western blot analysis of extracts from HUVEC cells, using AIM2 antibody.
Anti-AIM2 Antibody – Cat# MBS852493

Product References and Citations for anti-AIM2 antibody

DeYoung K.L., Oncogene 15:453-457(1997). Gregory S.G., Nature 441:315-321(2006).

Other Notes

Small volumes of anti-AIM2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for AIM2. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
interferon-inducible protein AIM2 isoform 1
NCBI Official Synonym Full Names
absent in melanoma 2
NCBI Official Symbol
AIM2
NCBI Official Synonym Symbols
PYHIN4
UniProt Protein Name
Interferon-inducible protein AIM2
UniProt Synonym Protein Names
Absent in melanoma 2
UniProt Gene Name
AIM2
NCBI Protein Information
interferon-inducible protein AIM2

NCBI Summary for AIM2

AIM2 is a member of the IFI20X /IFI16 family. It plays a putative role in tumorigenic reversion and may control cell proliferation. Interferon-gamma induces expression of AIM2. [provided by RefSeq, Jul 2008]

UniProt Comments for AIM2

Involved in innate immune response by recognizing cytosolic double-stranded DNA and inducing caspase-1-activating inflammasome formation in macrophages. Upon binding to DNA is thought to undergo oligomerization and to associate with PYCARD initiating the recruitment of caspase-1 precusrsor and processing of interleukin-1 beta and interleukin-18. Detects cytosolic dsDNA of viral and bacterial origin in a non-sequence-specific manner. Can also trigger PYCARD-dependent, caspase-1-independent cell death that involves caspase-8 (). Tumor suppressor which may act by repressing NF-kappa-B transcriptional activity.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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