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C2 Antibody

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1881170

MBS1881170 is an antibody targeting C2. Also known as PE-conjugated Anti-C2 (empasiprubart biosimilar) mAb. Reactive in Human. More details

$415 / 100 Tests +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
C2, Antibody
Full Product Name
PE-conjugated Anti-C2 (empasiprubart biosimilar) mAb
Product Gene Name
Product Synonym Names
CO2; ARMD14; ARGX-117; ARGX117
Isotype
IgG1
Species Reactivity
Human
Form/Format
Liquid, PBS with 0.05% Proclin300, 517% BSA
Preparation and Storage
Store at 2 degree C-8 degree C fo 6 months
Molecular Weight
69,444 Da
OMIM
217000
3D Structure
ModBase 3D Structure for P06681
Conjugation
PE-conjugated
Applications Tested/Suitable for anti-C2 antibody
Flow Cytometry (FC/FACS)
Application Notes for anti-C2 antibody
FC/FACS: 1:100

Other Notes

Small volumes of anti-C2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for C2. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
complement C2 isoform 1 preproprotein
NCBI Official Synonym Full Names
complement component 2
NCBI Official Symbol
C2
NCBI Official Synonym Symbols
CO2; ARMD14
UniProt Protein Name
Complement C2
UniProt Synonym Protein Names
C3/C5 convertase
Protein Family
UniProt Gene Name
C2
UniProt Entry Name
CO2_HUMAN
NCBI Protein Information
complement C2

NCBI Summary for C2

Component C2 is a serum glycoprotein that functions as part of the classical pathway of the complement system. Activated C1 cleaves C2 into C2a and C2b. The serine proteinase C2a then combines with complement factor 4b to create the C3 or C5 convertase. Deficiency of C2 has been reported to associated with certain autoimmune diseases and SNPs in this gene have been associated with altered susceptibility to age-related macular degeneration. This gene localizes within the class III region of the MHC on the short arm of chromosome 6. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants have been described in publications but their full-length sequence has not been determined.[provided by RefSeq, Mar 2009]
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UniProt Comments for C2

Component C2 which is part of the classical pathway of the complement system is cleaved by activated factor C1 into two fragments: C2b and C2a. C2a, a serine protease, then combines with complement factor C4b to generate the C3 or C5 convertase.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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