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CD10 Antibody – Mouse

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1800872

CD10 (neutral endopeptidase - NEP, common acute lymphocytic leukemia antigen - CALLA, membrane metallo-endopeptidase - MME, enkefalinase) is a 100-kDa cell surface zinc metalloprotease cleaving peptide bonds on the N-terminus of hydrophobic amino acids and… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
CD10, Antibody
Full Product Name
Anti-Hu CD10 FITC
Product Gene Name
Product Synonym Gene Name
MME
Product Synonym Names
membrane metalloendopeptidase; CALLA; Neprilysin; Neutral endopeptidase; Enkephalinase; Atriopeptidase; MME
Isotype
IgG1
Clone Number
LT10
Host
Mouse
Species Reactivity
Human
Form/Format
Stabilizing phosphate buffered saline (PBS) solution containing 15 mM sodium azide
Purity/Purification
The purified antibody is conjugated with fluorescein isothiocyanate (FITC) under optimum conditions. The conjugate is purified by size-exclusion chromatography.
Specificity
The antibody LT10 reacts with an extracellular epitope of CD10 (CALLA - Common acute lymphatic leukemia antigen), a 100 kDa type II integral membrane protein.
Preparation and Storage
Store in the dark at 2-8 degree C. Do not freeze. Avoid prolonged exposure to light.
Matching Pairs
Unconjugated Antibody: CD10 Clone #LT10 (MBS1800871)
FITC Conjugated Antibody: CD10 Clone #LT10 (MBS1800872)
OMIM
120520
3D Structure
ModBase 3D Structure for P08473
Immunogen
mouse NALM-6 leukemia pre-B cell line (tissue/cell preparation)
Conjugation
FITC
Applications Tested/Suitable for anti-CD10 antibody
Flow Cytometry (FC/FACS)
Application Notes for anti-CD10 antibody
FC/FACS: QC tested

Flow Cytometry (FC/FACS) of anti-CD10 antibody

Separation of human CD10 positive neutrophil granulocytes (red-filled) from human CD10 negative lymphocytes (black-dashed) in flow cytometry analysis (surface staining) of human peripheral whole blood stained using anti-human CD10 (LT10) FITC (20 ul reagent / 100 ul of peripheral whole blood).
Mouse Anti-CD10 Antibody – Cat# MBS1800872

Flow Cytometry (FC/FACS) of anti-CD10 antibody

Flow cytometry surface staining pattern of human peripheral whole blood stained using anti-human CD10 (LT10) FITC (20 ul reagent / 100 ul of peripheral whole blood).
Mouse Anti-CD10 Antibody, Flow Cytometry (FC/FACS) – Cat# MBS1800872

Other Notes

Small volumes of anti-CD10 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CD10 purchase

MBS1800872 is an antibody targeting CD10. Also known as Anti-Hu CD10 FITC. Reactive in Human. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for CD10. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
neprilysin isoform a
NCBI Official Synonym Full Names
membrane metalloendopeptidase
NCBI Official Symbol
MME
NCBI Official Synonym Symbols
NEP; SFE; CD10; CALLA; CMT2T; SCA43
UniProt Protein Name
Neprilysin
UniProt Synonym Protein Names
Atriopeptidase; Common acute lymphocytic leukemia antigen; CALLA; Enkephalinase; Neutral endopeptidase 24.11; NEP; Neutral endopeptidase; Skin fibroblast elastase
Protein Family
UniProt Gene Name
MME
UniProt Synonym Gene Names
EPN; CALLA; NEP; Neutral endopeptidase; SFE
UniProt Entry Name
NEP_HUMAN
NCBI Protein Information
neprilysin

NCBI Summary for CD10

The protein encoded by this gene is a type II transmembrane glycoprotein and a common acute lymphocytic leukemia antigen that is an important cell surface marker in the diagnosis of human acute lymphocytic leukemia (ALL). The encoded protein is present on leukemic cells of pre-B phenotype, which represent 85% of cases of ALL. This protein is not restricted to leukemic cells, however, and is found on a variety of normal tissues. The protein is a neutral endopeptidase that cleaves peptides at the amino side of hydrophobic residues and inactivates several peptide hormones including glucagon, enkephalins, substance P, neurotensin, oxytocin, and bradykinin. [provided by RefSeq, Aug 2017]
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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