Mouse Anti-CD371 Antibody – Cat# MBS2584648

Staining of normal human peripheral blood cells with Fluor<sup>®</sup> 700 Anti-Human CD371 Antibody[50C1](left) or Fluor<sup>®</sup> 700 Mouse IgG2a, κ Isotype Control(right). Cells in the leucocyte gate were used for analysis.

CD371 Antibody – Mouse

Name: CD371 Antibody; Mouse; Human-Reactive; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS2584648
Price: 175 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS2584648

MBS2584648 is an antibody targeting CD371. Also known as Fluor 700 Anti-Human CD371 Antibody [50C1]. Reactive in Human. Host: Mouse. More details

$175 / 20 Tests +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

CD371, Antibody

Full Product Name

Fluor 700 Anti-Human CD371 Antibody [50C1]

Product Gene Name

anti-CD371 antibody

Product Synonym Names

CLL1; MICL; CLL-1; DCAL-2; C-type lectin domain family 12 member A

Isotype

IgG2a, kappa

Clone Number

50C1

Host

Mouse

Species Reactivity

Human

Preparation and Storage

This product can be stored at 2-8 degree C for 12 months. Please protected from prolonged exposure to light and do not freeze.

Matching Pairs

Antibody: CD371 Clone #50C1 (MBS2584648)
Isotype Control: IgG1, kappa Clone #MOPC-21 (MBS2579320)

Molecular Weight

30,762 Da

Chromosome Location

Chromosome: 12; NC_000012.11 (10103915..10147704). Location: 12p13.2

OMIM

612088

3D Structure

ModBase 3D Structure for Q5QGZ9

Conjugation

Fluor700

Product Categories/Family for anti-CD371 antibody

Antibodies and Reagents; Primary Antibodies; Flow Cytometry Antibodies

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Applications Tested/Suitable for anti-CD371 antibody

Flow Cytometry (FC/FACS)

Other Notes

Small volumes of anti-CD371 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for CD371. It may not necessarily be applicable to this product.

NCBI GI #

160364

NCBI GeneID

160364

NCBI Accession #

NP_001193939.1

UniProt Primary Accession #

Q5QGZ9

UniProt Secondary Accession #

Q6P4H1; Q6RH77; Q6RH78; Q8TDQ6; B2RA16

UniProt Related Accession #

Q5QGZ9

GenBank Nucleotide #

NM_001207010.1

NCBI Official Full Name

C-type lectin domain family 12 member A isoform 3

NCBI Official Synonym Full Names

C-type lectin domain family 12, member A

NCBI Official Symbol

CLEC12A

NCBI Official Synonym Symbols

CLL1; MICL; CLL-1; DCAL-2

UniProt Protein Name

C-type lectin domain family 12 member A

UniProt Synonym Protein Names

C-type lectin-like molecule 1; CLL-1; Dendritic cell-associated lectin 2; DCAL-2; Myeloid inhibitory C-type lectin-like receptor

UniProt Gene Name

CLEC12A

UniProt Synonym Gene Names

CLL1; DCAL2; MICL; CLL-1; DCAL-2; MICL

UniProt Entry Name

CL12A_HUMAN

NCBI Protein Information

C-type lectin domain family 12 member A; C-type lectin superfamily; C-type lectin protein CLL-1; C-type lectin-like molecule-1; dendritic cell-associated lectin 2; myeloid inhibitory C-type lectin-like receptor

NCBI Summary for CD371

This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signaling, glycoprotein turnover, and roles in inflammation and immune response. The protein encoded by this gene is a negative regulator of granulocyte and monocyte function. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined. This gene is closely linked to other CTL/CTLD superfamily members in the natural killer gene complex region on chromosome 12p13. [provided by RefSeq, May 2011]

UniProt Comments for CD371

CLEC12A: Cell surface receptor that modulates signaling cascades and mediates tyrosine phosphorylation of target MAP kinases. 5 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: 12p13.2

Cellular Component: integral to membrane; plasma membrane

Molecular Function: carbohydrate binding

Research Articles on CD371

1. There is a potential genetic association of CLEC12A with rheumatoid arthritis (RA). Since CLEC12A encodes for the myeloid inhibitory C-type lectin-like receptor that modulates cytokine synthesis, this receptor may contribute to the pathogenesis of RA.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.