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CD56 Antibody – Mouse

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1801106

CD56 (NCAM, neural cell adhesion molecule) is a transmembrane glycoprotein of immunoglobulin family serving as adhesive molecule which is ubiquitously expressed in nervous system, usually as 120 kDa, 140 kDa or 180 kDa isoform, and it is also found on T cells… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
CD56, Antibody
Full Product Name
Anti-Hu CD56 APC
Product Gene Name
Product Synonym Gene Name
NCAM1
Product Synonym Names
neural cell adhesion molecule 1; NCAM1; NCAM-1; MSK39
Isotype
IgG2a
Clone Number
MEM-188
Host
Mouse
Species Reactivity
Non-human primates, Human
Form/Format
Stabilizing phosphate buffered saline (PBS) solution containing 15 mM sodium azide
Purity/Purification
The purified antibody is conjugated with allophycocyanin (APC) under optimum conditions. The conjugate is purified by size-exclusion chromatography.
Specificity
The antibody MEM-188 reacts with an extracellular epitope on a 180 kDa isoform of CD56 (NCAM) expressed in leukocytes. It has been suggested that the antibody MEM-188 could react with rhesus monkey lymphocytes. Reactivity with other NCAM isoforms has not been tested.
Preparation and Storage
Store in the dark at 2-8 degree C. Do not freeze. Avoid prolonged exposure to light.
Matching Pairs
Unconjugated Antibody: CD56 Clone #MEM-188 (MBS1801105)
APC Conjugated Antibody: CD56 Clone #MEM-188 (MBS1801106)
OMIM
116930
3D Structure
ModBase 3D Structure for P13591
Immunogen
KG-1 human acute myelogenous leukemia cell line
Conjugation
APC
Applications Tested/Suitable for anti-CD56 antibody
Flow Cytometry (FC/FACS)
Application Notes for anti-CD56 antibody
FC/FACS: QC tested

Flow Cytometry (FC/FACS) of anti-CD56 antibody

Flow cytometry surface staining pattern of human peripheral whole blood stained using anti-human CD56 (MEM-188) APC antibody (10 ul reagent / 100 ul of peripheral whole blood).
Mouse Anti-CD56 Antibody – Cat# MBS1801106

Flow Cytometry (FC/FACS) of anti-CD56 antibody

Flow cytometry surface staining pattern of human peripheral whole blood stained using anti-human CD56 (MEM-188) APC antibody (10 ul reagent / 100 ul of peripheral whole blood).
Mouse Anti-CD56 Antibody, Flow Cytometry (FC/FACS) – Cat# MBS1801106

Flow Cytometry (FC/FACS) of anti-CD56 antibody

Flow cytometry surface staining pattern of human peripheral whole blood stained using anti-human CD56 (MEM-188) APC antibody (10 ul reagent / 100 ul of peripheral whole blood).
Mouse Anti-CD56 Antibody, Flow Cytometry (FC/FACS) – Cat# MBS1801106

Other Notes

Small volumes of anti-CD56 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CD56 purchase

MBS1801106 is an antibody targeting CD56. Also known as Anti-Hu CD56 APC. Reactive in Non-human primates, Human. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for CD56. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
NCBI Official Full Name
Neural cell adhesion molecule 1
NCBI Official Synonym Full Names
neural cell adhesion molecule 1
NCBI Official Symbol
NCAM1
NCBI Official Synonym Symbols
CD56; NCAM; MSK39
UniProt Protein Name
Neural cell adhesion molecule 1
UniProt Synonym Protein Names
CD_antigen: CD56
UniProt Gene Name
NCAM1
UniProt Synonym Gene Names
NCAM; N-CAM-1; NCAM-1
UniProt Entry Name
NCAM1_HUMAN
NCBI Protein Information
neural cell adhesion molecule 1

NCBI Summary for CD56

This gene encodes a cell adhesion protein which is a member of the immunoglobulin superfamily. The encoded protein is involved in cell-to-cell interactions as well as cell-matrix interactions during development and differentiation. The encoded protein has been shown to be involved in development of the nervous system, and for cells involved in the expansion of T cells and dendritic cells which play an important role in immune surveillance. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2011]
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UniProt Comments for CD56

NCAM1: This protein is a cell adhesion molecule involved in neuron-neuron adhesion, neurite fasciculation, outgrowth of neurites, etc. 6 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, GPI anchor; Membrane protein, integral; Cell adhesion; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 11q23.1

Cellular Component: Golgi membrane; cell surface; membrane; integral to membrane; plasma membrane; external side of plasma membrane

Molecular Function: identical protein binding

Biological Process: axon guidance; extracellular matrix organization and biogenesis; cytokine and chemokine mediated signaling pathway; cell adhesion
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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