IL36RN Antibody

Name: IL36RN Antibody; Human-Reactive; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS1881986
Price: 415 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1881986

MBS1881986 is an antibody targeting IL36RN. Also known as PE-conjugated Anti-IL36RN (spesolimab biosimilar) mAb. Reactive in Human. More details

$415 / 100 Tests +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

IL36RN, Antibody

Full Product Name

PE-conjugated Anti-IL36RN (spesolimab biosimilar) mAb

Product Gene Name

anti-IL36RN antibody

Product Synonym Names

FIL1; FIL1D; IL1F5; IL1L1; PSORP; IL1HY1; IL1RP3; IL36RA; IL-36Ra; PSORS14; FIL1(DELTA); BI 655130; BI655130; BI-655130; SPEVIGO

Isotype

IgG1

Species Reactivity

Human

Form/Format

Liquid, PBS with 0.05% Proclin300, 789% BSA

Preparation and Storage

Store at 2 degree C-8 degree C fo 6 months

Molecular Weight

16,962 Da

OMIM

605507

3D Structure

ModBase 3D Structure for Q9UBH0

Conjugation

PE-conjugated

Product Categories/Family for anti-IL36RN antibody

Biosimilar reference antibodies

Applications Tested/Suitable for anti-IL36RN antibody

Flow Cytometry (FC/FACS)

Application Notes for anti-IL36RN antibody

FC/FACS: 1:100

Other Notes

Small volumes of anti-IL36RN antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for IL36RN. It may not necessarily be applicable to this product.

NCBI GI #

6912432

NCBI GeneID

26525

NCBI Accession #

NP_036407.1

UniProt Primary Accession #

Q9UBH0

UniProt Secondary Accession #

Q56AT9; Q7RTZ6; A8K2I4

UniProt Related Accession #

Q9UBH0

GenBank Nucleotide #

NM_012275.2

NCBI Official Full Name

interleukin-36 receptor antagonist protein

NCBI Official Synonym Full Names

interleukin 36 receptor antagonist

NCBI Official Symbol

IL36RN

NCBI Official Synonym Symbols

FIL1; FIL1D; IL1F5; IL1L1; PSORP; IL1HY1; IL1RP3; IL36RA; IL-36Ra; PSORS14; FIL1(DELTA)

UniProt Protein Name

Interleukin-36 receptor antagonist protein

UniProt Synonym Protein Names

FIL1 delta; IL-1-related protein 3; IL-1RP3; Interleukin-1 HY1; IL-1HY1; Interleukin-1 delta; IL-1 delta; Interleukin-1 family member 5; IL-1F5; Interleukin-1 receptor antagonist homolog 1; IL-1ra homolog 1; Interleukin-1-like protein 1; IL-1L1

Protein Family

Interleukin-36 receptor antagonist protein

UniProt Gene Name

IL36RN

UniProt Synonym Gene Names

FIL1D; IL1F5; IL1HY1; IL1L1; IL1RP3; IL-1RP3; IL-1HY1; IL-1 delta; IL-1F5; IL-1ra homolog 1; IL-1L1

UniProt Entry Name

I36RA_HUMAN

NCBI Protein Information

interleukin-36 receptor antagonist protein

UniProt Comments for IL36RN

IL1F5: Is a highly and a specific antagonist of the IL-1 receptor-related protein 2-mediated response to interleukin 1 family member 9 (IL1F9). Could constitute part of an independent signaling system analogous to interleukin-1 alpha (IL-1A), beta (IL-1B) receptor agonist and interleukin-1 receptor type I (IL- 1R1), that is present in epithelial barriers and takes part in local inflammatory response. Defects in IL36RN are the cause of psoriasis generalized pustular (PSORP). PSORP is a life-threatening disease defined by repeated flares of sudden onset consisting of diffuse erythematous skin eruption characterized by rapid coverage with pustules, high-grade fever, asthenia, marked leukocytosis, and elevated serum levels of C-reactive protein. Belongs to the IL-1 family.

Protein type: Cytokine

Chromosomal Location of Human Ortholog: 2q14

Cellular Component: extracellular space

Molecular Function: cytokine activity; interleukin-1 receptor binding; protein binding

Biological Process: antifungal humoral response; negative regulation of cytokine and chemokine mediated signaling pathway; negative regulation of interleukin-17 production

Disease: Psoriasis 14, Pustular

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Diseases associated with anti-IL36RN antibody

Disease Name	Pubmed Publications
Inflammation Antibodies	>9 publications with IL36RN and Inflammation
Hypersensitivity Antibodies	>4 publications with IL36RN and Hypersensitivity
Autoimmune Diseases Antibodies	>2 publications with IL36RN and Autoimmune Diseases
Congenital Abnormalities Antibodies	>2 publications with IL36RN and Congenital Abnormalities
Necrosis Antibodies	>2 publications with IL36RN and Necrosis
Disease Models, Animal Antibodies	>2 publications with IL36RN and Disease Models, Animal
Leukocytosis Antibodies	>1 publications with IL36RN and Leukocytosis
Heart Diseases Antibodies	>1 publications with IL36RN and Heart Diseases
Lung Diseases Antibodies	>1 publications with IL36RN and Lung Diseases

Organs/Tissues associated with anti-IL36RN antibody

Organ/Tissue Name	Pubmed Publications
Lung Antibodies	>2 publications with IL36RN and Lung
Muscle Antibodies	>2 publications with IL36RN and Muscle
Testis Antibodies	>1 publications with IL36RN and Testis
Cervix Antibodies	>1 publications with IL36RN and Cervix
Mouth Antibodies	>1 publications with IL36RN and Mouth
Parathyroid Antibodies	>1 publications with IL36RN and Parathyroid
Placenta Antibodies	>1 publications with IL36RN and Placenta