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MED13 Antibody

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS851942

MBS851942 is an antibody targeting MED13. Also known as MED13 Antibody. Reactive in Human. More details

$380 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
MED13, Antibody
Full Product Name
MED13 Antibody
Product Gene Name
Product Synonym Names
ARC250; Activator-recruited cofactor 250 kDa component; KIAA0593; T240; THRAP1; TR240; Thyroid hormone receptor associated protein 1; Thyroid hormone receptor-associated protein complex 240 kDa component
Species Reactivity
Human
Form/Format
In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Specificity
MED13 antibody detects endogenous levels of total MED13 protein.
Preparation and Storage
Store at-20 degree C for 1 year.
Molecular Weight
239,297 Da
OMIM
603808
3D Structure
ModBase 3D Structure for Q9UHV7
Immunogen
The antiserum was produced against synthesized peptide derived from internal of human MED13.
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-MED13 antibody
Immunohistochemistry (IHC), ELISA (EIA)
Application Notes for anti-MED13 antibody
IHC: 1:50-1:100
ELISA: 1:40000

Immunohistochemistry (IHC) of anti-MED13 antibody

Peptide-+ Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue, using MED13 antibody.
Anti-MED13 Antibody – Cat# MBS851942

Product References and Citations for anti-MED13 antibody

Olsen J.V., Cell 127:635-648(2006). Beausoleil S.A., Proc. Natl. Acad. Sci. U.S.A. 101:12130-12135(2004). Naeaer A.M., Nature 398:828-832(1999).

Other Notes

Small volumes of anti-MED13 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for MED13. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
mediator of RNA polymerase II transcription subunit 13
NCBI Official Synonym Full Names
mediator complex subunit 13
NCBI Official Symbol
MED13
NCBI Official Synonym Symbols
ARC250; THRAP1; DRIP250; HSPC221; TRAP240
UniProt Protein Name
Mediator of RNA polymerase II transcription subunit 13
UniProt Synonym Protein Names
Activator-recruited cofactor 250 kDa component; ARC250; Mediator complex subunit 13; Thyroid hormone receptor-associated protein 1; Thyroid hormone receptor-associated protein complex 240 kDa component; Trap240; Vitamin D3 receptor-interacting protein complex component DRIP250; DRIP250
UniProt Gene Name
MED13
UniProt Synonym Gene Names
ARC250; KIAA0593; THRAP1; TRAP240; ARC250; Trap240; DRIP250
NCBI Protein Information
mediator of RNA polymerase II transcription subunit 13

NCBI Summary for MED13

This gene encodes a component of the mediator complex (also known as TRAP, SMCC, DRIP, or ARC), a transcriptional coactivator complex thought to be required for the expression of almost all genes. The mediator complex is recruited by transcriptional activators or nuclear receptors to induce gene expression, possibly by interacting with RNA polymerase II and promoting the formation of a transcriptional pre-initiation complex. The product of this gene is proposed to form a sub-complex with MED12, cyclin C, and CDK8 that can negatively regulate transactivation by mediator. [provided by RefSeq, Jul 2008]
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UniProt Comments for MED13

Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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