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MSH3 Antibody

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS8514354

MBS8514354 is an antibody targeting MSH3. Also known as MSH3 Antibody. Reactive in Human. More details

$380 / 0.1 mg +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
MSH3, Antibody
Full Product Name
MSH3 Antibody
Product Gene Name
Product Synonym Names
DNA mismatch repair protein Msh3; Divergent upstream protein; DUP; Mismatch repair protein 1; MRP1; MSH3; DUC1; DUG
Species Reactivity
Human
Form/Format
In phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purity/Purification
Immunogen affinity purified
Specificity
MSH3 Antibody detects endogenous levels of total MSH3
Preparation and Storage
Store at-20 degree C for 1 year
Molecular Weight
127 KD
OMIM
600887
3D Structure
ModBase 3D Structure for P20585
Immunogen
A synthesized peptide
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-MSH3 antibody
Western Blot (WB)
Application Notes for anti-MSH3 antibody
WB: 1:500-1:1000

Western Blot (WB) of anti-MSH3 antibody

Western blot analysis of extracts from HUVEC cells, using MSH3 antibody.
Anti-MSH3 Antibody – Cat# MBS8514354

Other Notes

Small volumes of anti-MSH3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for MSH3. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
DNA mismatch repair protein Msh3
NCBI Official Synonym Full Names
mutS homolog 3
NCBI Official Symbol
MSH3
NCBI Official Synonym Symbols
DUP; FAP4; MRP1
UniProt Protein Name
DNA mismatch repair protein Msh3
UniProt Synonym Protein Names
Divergent upstream protein; DUP; Mismatch repair protein 1; MRP1
UniProt Gene Name
MSH3
UniProt Synonym Gene Names
DUC1; DUG; hMSH3; DUP; MRP1
NCBI Protein Information
DNA mismatch repair protein Msh3

NCBI Summary for MSH3

The protein encoded by this gene forms a heterodimer with MSH2 to form MutS beta, part of the post-replicative DNA mismatch repair system. MutS beta initiates mismatch repair by binding to a mismatch and then forming a complex with MutL alpha heterodimer. This gene contains a polymorphic 9 bp tandem repeat sequence in the first exon. The repeat is present 6 times in the reference genome sequence and 3-7 repeats have been reported. Defects in this gene are a cause of susceptibility to endometrial cancer. [provided by RefSeq, Mar 2011]
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UniProt Comments for MSH3

Component of the post-replicative DNA mismatch repair system (MMR). Heterodimerizes with MSH2 to form MutS beta which binds to DNA mismatches thereby initiating DNA repair. When bound, the MutS beta heterodimer bends the DNA helix and shields approximately 20 base pairs. MutS beta recognizes large insertion-deletion loops (IDL) up to 13 nucleotides long. After mismatch binding, forms a ternary complex with the MutL alpha heterodimer, which is thought to be responsible for directing the downstream MMR events, including strand discrimination, excision, and resynthesis.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-MSH3 antibody

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