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TINF2 Antibody

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS854417

MBS854417 is an antibody targeting TINF2. Also known as TINF2 Antibody. Reactive in Human. More details

$380 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
TINF2, Antibody
Full Product Name
TINF2 Antibody
Product Gene Name
Product Synonym Names
TRF1-interacting nuclear protein 2; TERF1-interacting nuclear factor 2; TINF2; TIN2
Species Reactivity
Human
Form/Format
In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Specificity
TINF2 antibody detects endogenous levels of total TINF2 protein.
Preparation and Storage
Store at-20 degree C for 1 year.
Molecular Weight
15,434 Da
OMIM
268130
3D Structure
ModBase 3D Structure for Q9BSI4
Immunogen
The antiserum was produced against synthesized peptide derived from internal of human TINF2.
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-TINF2 antibody
Western Blot (WB), ELISA (EIA)
Application Notes for anti-TINF2 antibody
WB: 1:500-1:1000
ELISA: 1:10000

Western Blot (WB) of anti-TINF2 antibody

Western blot analysis of extracts from HUVEC cells, using TINF2 antibody.
Anti-TINF2 Antibody – Cat# MBS854417

Product References and Citations for anti-TINF2 antibody

Kim S.-H., Nat. Genet. 23:405-412(1999). Ota T., Nat. Genet. 36:40-45(2004). Loayza D., Nature 423:1013-1018(2003).

Other Notes

Small volumes of anti-TINF2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for TINF2. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
TERF1-interacting nuclear factor 2 isoform 1
NCBI Official Synonym Full Names
TERF1 interacting nuclear factor 2
NCBI Official Symbol
TINF2
NCBI Official Synonym Symbols
TIN2; DKCA3
UniProt Protein Name
TERF1-interacting nuclear factor 2
UniProt Synonym Protein Names
TRF1-interacting nuclear protein 2
UniProt Gene Name
TINF2
UniProt Synonym Gene Names
TIN2
NCBI Protein Information
TERF1-interacting nuclear factor 2

NCBI Summary for TINF2

This gene encodes one of the proteins of the shelterin, or telosome, complex which protects telomeres by allowing the cell to distinguish between telomeres and regions of DNA damage. The protein encoded by this gene is a critical part of shelterin; it interacts with the three DNA-binding proteins of the shelterin complex, and it is important for assembly of the complex. Mutations in this gene cause dyskeratosis congenita (DKC), an inherited bone marrow failure syndrome. [provided by RefSeq, Mar 2010]
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UniProt Comments for TINF2

Component of the shelterin complex (telosome) that is involved in the regulation of telomere length and protection. Shelterin associates with arrays of double-stranded TTAGGG repeats added by telomerase and protects chromosome ends; without its protective activity, telomeres are no longer hidden from the DNA damage surveillance and chromosome ends are inappropriately processed by DNA repair pathways. Plays a role in shelterin complex assembly. Isoform 1 may have additional role in tethering telomeres to the nuclear matrix.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-TINF2 antibody

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