ARHGAP27 Peptide - N-Terminal Region Blocking Peptide

Name: ARHGAP27 Peptide - N-Terminal Region Blocking Peptide; MyBioSource
Brand: MyBioSource
SKU: MBS3242356
Price: 195 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3242356

This is a synthetic peptide designed for use in combination with anti-ARHGAP27 Antibody, madeTarget Description: Rho-like small GTPases are involved in many cellular processes, and they are inactive in the GDP-bound state and active in the GTP-bound state.… More details

$195 / 0.1 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

ARHGAP27, Blocking Peptide

Full Product Name

ARHGAP27 Peptide - N-terminal region

Product Gene Name

ARHGAP27 blocking peptide

Product Synonym Gene Name

CAMGAP1; FLJ35572; FLJ43547; MGC120624

Sequence

GVLHRTKTAD KGKRLRKKHW SASWTVLEGG VLTFFKDSKT SAAGGLRQPS

Species Reactivity

Human

Form/Format

Lyophilized powder

Preparation and Storage

Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20 degree C. Avoid repeat freeze-thaw cycles.

Antibody/Peptide Pairs

ARHGAP27 peptide (MBS3242356) is used for blocking the activity of ARHGAP27 antibody (MBS3217460)

Molecular Weight

60kDa

OMIM

610591

Product Categories/Family for ARHGAP27 blocking peptide

Peptide

Applications Tested/Suitable for ARHGAP27 blocking peptide

Western Blot (WB)

Other Notes

Small volumes of ARHGAP27 blocking peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for ARHGAP27 purchase

MBS3242356 is a blocking peptide targeting ARHGAP27. Also known as ARHGAP27 Peptide - N-terminal region. Reactive in Human.

Additional Details

NCBI/Uniprot data below describe general gene information for ARHGAP27. It may not necessarily be applicable to this product.

NCBI GI #

40548322

NCBI GeneID

201176

NCBI Accession #

NP_954976

UniProt Primary Accession #

Q6ZUM4

UniProt Related Accession #

Q6ZUM4

GenBank Nucleotide #

NM_199282

NCBI Official Full Name

rho GTPase-activating protein 27 isoform a

NCBI Official Synonym Full Names

Rho GTPase activating protein 27

NCBI Official Symbol

ARHGAP27

NCBI Official Synonym Symbols

PP905; SH3D20; SH3P20; CAMGAP1

UniProt Protein Name

Rho GTPase-activating protein 27

UniProt Synonym Protein Names

CIN85-associated multi-domain-containing Rho GTPase-activating protein 1; Rho-type GTPase-activating protein 27; SH3 domain-containing protein 20

Protein Family

Rho GTPase-activating protein

UniProt Gene Name

ARHGAP27

UniProt Synonym Gene Names

CAMGAP1; SH3D20

UniProt Entry Name

RHG27_HUMAN

NCBI Protein Information

rho GTPase-activating protein 27

NCBI Summary for ARHGAP27

This gene encodes a member of a large family of proteins that activate Rho-type guanosine triphosphate (GTP) metabolizing enzymes. The encoded protein may pay a role in clathrin-mediated endocytosis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Aug 2013]

UniProt Comments for ARHGAP27

Function: Rho GTPase-activating protein which may be involved in clathrin-mediated endocytosis. GTPase activators for the Rho-type GTPases act by converting them to an inactive GDP-bound state. Has activity toward CDC42 and RAC1

By similarity.

Subunit structure: Interacts with SH3KBP1/CIN85

By similarity.

Subcellular location: Cytoplasm

By similarity. Membrane; Peripheral membrane protein

By similarity.

Tissue specificity: Expressed in germinal center B-cell, spleen, chronic lymphocytic leukemia, pancreatic cancer and lung cancer. Ref.5

Sequence similarities: Contains 1 PH domain.Contains 1 Rho-GAP domain.Contains 1 SH3 domain.Contains 3 WW domains.

Caution: According to HGNC, ARHGAP27 and SH3D20 are 2 separate genes, corresponding to isoform 2 and isoform 4, respectively. However, a rat transcript and paralog proteins with a similar domain structure suggest the existence of a single gene encoding for a protein of 889 residues as displayed here.

Sequence caution: The sequence AAI01389.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.The sequence AAI01390.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.The sequence AAI01391.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.