CD33 Peptide - N-Terminal Region Blocking Peptide

Name: CD33 Peptide - N-Terminal Region Blocking Peptide; MyBioSource
Brand: MyBioSource
SKU: MBS3240766
Price: 195 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3240766

This is a synthetic peptide designed for use in combination with anti-CD33 Antibody, madeTarget Description: CD33 is a putative adhesion molecule of myelomonocytic-derived cells that mediates sialic-acid dependent binding to cells. CD33 preferentially binds… More details

$195 / 0.1 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

CD33, Blocking Peptide

Full Product Name

CD33 Peptide - N-terminal region

Product Gene Name

CD33 blocking peptide

Product Synonym Gene Name

FLJ00391; SIGLEC-3; SIGLEC3; p67

Sequence

HPIPYYDKNS PVHGYWFREG AIISRDSPVA TNKLDQEVQE ETQGRFRLLG

Species Reactivity

Human

Form/Format

Lyophilized powder

Preparation and Storage

Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20 degree C. Avoid repeat freeze-thaw cycles.

Antibody/Peptide Pairs

CD33 peptide (MBS3240766) is used for blocking the activity of CD33 antibody (MBS3215864)

Molecular Weight

38kDa

OMIM

159590

Product Categories/Family for CD33 blocking peptide

Peptide

Applications Tested/Suitable for CD33 blocking peptide

Western Blot (WB)

Other Notes

Small volumes of CD33 blocking peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CD33 purchase

MBS3240766 is a blocking peptide targeting CD33. Also known as CD33 Peptide - N-terminal region. Reactive in Human.

Additional Details

NCBI/Uniprot data below describe general gene information for CD33. It may not necessarily be applicable to this product.

NCBI GI #

130979981

NCBI GeneID

945

NCBI Accession #

NP_001763

UniProt Primary Accession #

P20138

UniProt Related Accession #

P20138

GenBank Nucleotide #

NM_001772

NCBI Official Full Name

myeloid cell surface antigen CD33 isoform 1

NCBI Official Synonym Full Names

CD33 molecule

NCBI Official Symbol

CD33

NCBI Official Synonym Symbols

p67; SIGLEC3; SIGLEC-3

UniProt Protein Name

Myeloid cell surface antigen CD33

UniProt Synonym Protein Names

Sialic acid-binding Ig-like lectin 3; Siglec-3; gp67; CD_antigen: CD33

Protein Family

Myeloid cell surface antigen

UniProt Gene Name

CD33

UniProt Synonym Gene Names

SIGLEC3; Siglec-3

UniProt Entry Name

CD33_HUMAN

NCBI Protein Information

myeloid cell surface antigen CD33

UniProt Comments for CD33

CD33: Putative adhesion molecule of myelomonocytic-derived cells that mediates sialic-acid dependent binding to cells. Preferentially binds to alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. In the immune response, may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase(s) via their SH2 domain(s) that block signal transduction through dephosphorylation of signaling molecules. Induces apoptosis in acute myeloid leukemia (in vitro). Belongs to the immunoglobulin superfamily. SIGLEC (sialic acid binding Ig-like lectin) family.

Protein type: Membrane protein, integral; Cell adhesion

Chromosomal Location of Human Ortholog: 19q13.3

Cellular Component: integral to plasma membrane; plasma membrane; external side of plasma membrane

Molecular Function: protein binding; receptor activity; carbohydrate binding

Biological Process: negative regulation of cell proliferation; cell-cell signaling; signal transduction; cell adhesion

Research Articles on CD33

1. These findings demonstrate that C1q and it's globular region interact with CD33 to activate its inhibitory motifs, while the collagen-like region does not. Whole C1q is required to crosslink CD33 and LAIR-1 and concurrently activate CD33/LAIR-1 inhibitory motifs.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with CD33 blocking peptide

Reference Product	PubMed Publications
CD34 blocking peptide	>1066 publications with CD33 and CD34
SRC blocking peptide	>20 publications with CD33 and SRC
PTPN11 blocking peptide	>11 publications with CD33 and PTPN11
PTPN6 blocking peptide	>7 publications with CD33 and PTPN6
CBL blocking peptide	>3 publications with CD33 and CBL
UBC blocking peptide	>3 publications with CD33 and UBC
PVR blocking peptide	>1 publications with CD33 and PVR

Pathways associated with CD33 blocking peptide

Products by Pathway	Pathway Diagram
Hematopoietic Cell Lineage Pathway antibodies	Hematopoietic Cell Lineage Pathway Diagram
Hematopoietic Cell Lineage Pathway antibodies	Hematopoietic Cell Lineage Pathway Diagram

Diseases associated with CD33 blocking peptide

Disease Name	Pubmed Publications
Leukemia, Myeloid Antibodies	>1323 publications with CD33 and Leukemia, Myeloid
Leukemia, Myeloid, Acute Antibodies	>1160 publications with CD33 and Leukemia, Myeloid, Acute
Hematologic Diseases Antibodies	>412 publications with CD33 and Hematologic Diseases
Bone Marrow Diseases Antibodies	>314 publications with CD33 and Bone Marrow Diseases
Necrosis Antibodies	>92 publications with CD33 and Necrosis
Death Antibodies	>78 publications with CD33 and Death
Cardiovascular Diseases Antibodies	>77 publications with CD33 and Cardiovascular Diseases
Inflammation Antibodies	>67 publications with CD33 and Inflammation
Respiratory Tract Diseases Antibodies	>44 publications with CD33 and Respiratory Tract Diseases
Brain Diseases Antibodies	>41 publications with CD33 and Brain Diseases

Organs/Tissues associated with CD33 blocking peptide

Organ/Tissue Name	Pubmed Publications
Blood Antibodies	>1416 publications with CD33 and Blood
Bone Antibodies	>983 publications with CD33 and Bone
Bone Marrow Antibodies	>972 publications with CD33 and Bone Marrow
Liver Antibodies	>85 publications with CD33 and Liver
Lymph Node Antibodies	>53 publications with CD33 and Lymph Node
Lung Antibodies	>50 publications with CD33 and Lung
Brain Antibodies	>31 publications with CD33 and Brain
Thymus Antibodies	>29 publications with CD33 and Thymus
Kidney Antibodies	>19 publications with CD33 and Kidney
Prostate Antibodies	>10 publications with CD33 and Prostate