CNGA4 Peptide - N-Terminal Region Blocking Peptide

Name: CNGA4 Peptide - N-Terminal Region Blocking Peptide; MyBioSource
Brand: MyBioSource
SKU: MBS3232521
Price: 195 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3232521

This is a synthetic peptide designed for use in combination with anti-CNGA4 Antibody, madeTarget Description: CNGA4 is a modulatory subunit of vertebrate cyclic nucleotide-gated membrane channels that transduce odorant signalsã€‚ More details

$195 / 0.1 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

CNGA4, Blocking Peptide

Full Product Name

CNGA4 Peptide - N-terminal region

Product Gene Name

CNGA4 blocking peptide

Sequence

Synthetic peptide located within the following region: RIAKLMLYIF VVIHWNSCLY FALSRYLGFG RDAWVYPDPA QPGFERLRRQ

Species Reactivity

Human

Form/Format

Lyophilized powder

Preparation and Storage

Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20 degree C. Avoid repeat freeze-thaw cycles.

Antibody/Peptide Pairs

CNGA4 peptide (MBS3232521) is used for blocking the activity of CNGA4 antibody (MBS3207556)

Molecular Weight

45kDa

OMIM

609472

Product Categories/Family for CNGA4 blocking peptide

Peptide

Applications Tested/Suitable for CNGA4 blocking peptide

Western Blot (WB)

Other Notes

Small volumes of CNGA4 blocking peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CNGA4 purchase

MBS3232521 is a blocking peptide targeting CNGA4. Also known as CNGA4 Peptide - N-terminal region. Reactive in Human.

Additional Details

NCBI/Uniprot data below describe general gene information for CNGA4. It may not necessarily be applicable to this product.

NCBI GI #

82617546

NCBI GeneID

1262

NCBI Accession #

NP_001032406.1

UniProt Primary Accession #

Q8IV77

UniProt Related Accession #

Q8IV77

GenBank Nucleotide #

NM_001037329.3

NCBI Official Full Name

cyclic nucleotide-gated cation channel alpha-4

NCBI Official Synonym Full Names

cyclic nucleotide gated channel alpha 4

NCBI Official Symbol

CNGA4

NCBI Official Synonym Symbols

CNG4; CNG5; CNCA2; CNG-4; CNGB2; OCNC2; OCNCb; OCNCBETA

UniProt Protein Name

Cyclic nucleotide-gated cation channel alpha-4

UniProt Synonym Protein Names

Cyclic nucleotide-gated channel alpha-4; CNG channel alpha-4; CNG-4; CNG4

Protein Family

Cyclic nucleotide-gated cation channel

UniProt Gene Name

CNGA4

UniProt Synonym Gene Names

CNG channel alpha-4; CNG-4; CNG4

UniProt Entry Name

CNGA4_HUMAN

NCBI Protein Information

cyclic nucleotide-gated cation channel alpha-4

NCBI Summary for CNGA4

CNGA4 is a modulatory subunit of vertebrate cyclic nucleotide-gated membrane channels that transduce odorant signals (Munger et al., 2001 [PubMed 11739959]).[supplied by OMIM, Mar 2008]

UniProt Comments for CNGA4

CNGA4: Second messenger, cAMP, causes the opening of cation- selective cyclic nucleotide-gated (CNG) channels and depolarization of the neuron (olfactory sensory neurons, OSNs). CNGA4 is the modulatory subunit of this channel which is known to play a central role in the transduction of odorant signals and subsequent adaptation. By accelerating the calcium-mediated negative feedback in olfactory signaling it allows rapid adaptation to odor stimulation and extends its range of odor detection. Belongs to the cyclic nucleotide-gated cation channel (TC 1.A.1.5) family. CNGA4 subfamily. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 11p15.4

Cellular Component: Golgi membrane; integral to plasma membrane

Molecular Function: voltage-gated potassium channel activity; intracellular cAMP activated cation channel activity; intracellular cGMP activated cation channel activity; cGMP binding; cAMP binding

Biological Process: phototransduction, visible light; regulation of membrane potential; organelle organization and biogenesis; sensory perception of smell

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with CNGA4 blocking peptide

Products by Pathway	Pathway Diagram
Assembly Of The Primary Cilium Pathway antibodies	Assembly Of The Primary Cilium Pathway Diagram
Cargo Trafficking To The Periciliary Membrane Pathway antibodies	Cargo Trafficking To The Periciliary Membrane Pathway Diagram
Olfactory Transduction Pathway antibodies	Olfactory Transduction Pathway Diagram
Olfactory Transduction Pathway antibodies	Olfactory Transduction Pathway Diagram
Organelle Biogenesis And Maintenance Pathway antibodies	Organelle Biogenesis And Maintenance Pathway Diagram
VxPx Cargo-targeting To Cilium Pathway antibodies	VxPx Cargo-targeting To Cilium Pathway Diagram
CAMP Signaling Pathway antibodies	CAMP Signaling Pathway Diagram
CAMP Signaling Pathway antibodies	CAMP Signaling Pathway Diagram

Organs/Tissues associated with CNGA4 blocking peptide

Organ/Tissue Name	Pubmed Publications
Brain Antibodies	>4 publications with CNGA4 and Brain