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CNOT9 Peptide - N-Terminal Region Blocking Peptide

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3246791

This gene encodes a member of the highly conserved RCD1 protein family. The encoded protein is a transcriptional cofactor and a core protein of the CCR4-NOT complex. It may be involved in signal transduction as well as retinoic acid-regulated cell… More details

$195 / 0.1 mg +1 FREE 8GB USB
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Testing Data View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
CNOT9, Blocking Peptide
Full Product Name
CNOT9 Peptide - N-terminal region
Product Gene Name
CNOT9 blocking peptide
Product Synonym Gene Name
RCD1; CAF40; CT129; RCD-1; RQCD1; CNOT9
Sequence
Synthetic peptide located within the following region: YQWINELSSP ETRENALLEL SKKRESVPDL APMLWHSFGT IAALLQEIVN
Species Reactivity
Human
Form/Format
Lyophilized powder
Preparation and Storage
Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20 degree C. Avoid repeat freeze-thaw cycles.
Antibody/Peptide Pairs
CNOT9 peptide (MBS3246791) is used for blocking the activity of CNOT9 antibody (MBS3222084)
Molecular Weight
32 kDa
OMIM
612054

Product Categories/Family for CNOT9 blocking peptide

Peptide

Other Notes

Small volumes of CNOT9 blocking peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CNOT9 purchase

MBS3246791 is a blocking peptide targeting CNOT9. Also known as CNOT9 Peptide - N-terminal region. Reactive in Human.

Additional Details

NCBI/Uniprot data below describe general gene information for CNOT9. It may not necessarily be applicable to this product.

NCBI GI #
4885579
NCBI GeneID
9125
NCBI Accession #
NP_005435.1
UniProt Primary Accession #
Q92600
UniProt Related Accession #
Q92600
GenBank Nucleotide #
NM_001271634.1
NCBI Official Full Name
CCR4-NOT transcription complex subunit 9 isoform 2
NCBI Official Synonym Full Names
CCR4-NOT transcription complex subunit 9
NCBI Official Symbol
CNOT9
NCBI Official Synonym Symbols
RCD1; CAF40; CT129; RCD-1; RQCD1
UniProt Protein Name
Cell differentiation protein RCD1 homolog
UniProt Synonym Protein Names
CCR4-NOT transcription complex subunit 9
UniProt Gene Name
RQCD1
UniProt Synonym Gene Names
CNOT9; RCD1; Rcd-1
UniProt Entry Name
RCD1_HUMAN
NCBI Protein Information
CCR4-NOT transcription complex subunit 9

UniProt Comments for CNOT9

RQCD1: Transcription factor that down-regulates MYB- and JUN- dependent transcription. May play a role in cell differentiation. Can bind oligonucleotides, such as poly-G, poly-C or poly-T (in vitro), but the physiological relevance of this is not certain. Does not bind poly-A. Enhances ligand-dependent transcriptional activity of nuclear hormone receptors, including RARA, expect ESR1-mediated transcription that is not only slightly increased, if at all. Belongs to the RCD1 family.

Protein type: Cancer Testis Antigen (CTA)

Chromosomal Location of Human Ortholog: 2q35

Cellular Component: membrane; nucleus; cytosol; CCR4-NOT complex

Molecular Function: protein domain specific binding; protein binding; protein homodimerization activity

Biological Process: regulation of translation; poly(A) tail shortening; transcription, DNA-dependent; regulation of transcription, DNA-dependent; cytokine and chemokine mediated signaling pathway; gene expression; RNA-mediated gene silencing; sex differentiation; mRNA catabolic process, deadenylation-dependent decay; negative regulation of estrogen receptor signaling pathway
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Research Articles on CNOT9

1. Data indicate a recurrent somatic C > T change causing a P131L mutation in the RQCD1 (Required for Cell Differentiation1 Homolog) gene identified through whole exome sequencing of 20 metastatic melanomas.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with CNOT9 blocking peptide

 Reference Product  PubMed Publications
 CNOT1 blocking peptide  >3 publications with CNOT9 and CNOT1
 CNOT7 blocking peptide  >1 publications with CNOT9 and CNOT7
 CNOT6 blocking peptide  >1 publications with CNOT9 and CNOT6

Pathways associated with CNOT9 blocking peptide

 Products by Pathway  Pathway Diagram
 Deadenylation Of MRNA Pathway antibodies  Deadenylation Of MRNA Pathway Diagram
 Deadenylation-dependent MRNA Decay Pathway antibodies  Deadenylation-dependent MRNA Decay Pathway Diagram
 Gene Expression Pathway antibodies  Gene Expression Pathway Diagram
 RNA Degradation Pathway antibodies  RNA Degradation Pathway Diagram
 RNA Degradation Pathway antibodies  RNA Degradation Pathway Diagram

Diseases associated with CNOT9 blocking peptide

 Disease Name  Pubmed Publications
 Breast Neoplasms Antibodies  >2 publications with CNOT9 and Breast Neoplasms

Organs/Tissues associated with CNOT9 blocking peptide

 Organ/Tissue Name  Pubmed Publications
 Muscle Antibodies  >1 publications with CNOT9 and Muscle
 Embryonic Tissue Antibodies  >1 publications with CNOT9 and Embryonic Tissue
 Blood Antibodies  >1 publications with CNOT9 and Blood
 Lung Antibodies  >1 publications with CNOT9 and Lung
 Testis Antibodies  >1 publications with CNOT9 and Testis
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