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CTPS Peptide - C-Terminal Region Blocking Peptide

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3246934

This gene encodes an enzyme responsible for the catalytic conversion of UTP (uridine triphosphate) to CTP (cytidine triphospate). This reaction is an important step in the biosynthesis of phospholipids and nucleic acids. Activity of this proten is important… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
CTPS1, Blocking Peptide
Full Product Name
CTPS Peptide - C-terminal region
Product Gene Name
CTPS1 blocking peptide
Product Synonym Gene Name
CTPS; IMD24
Sequence
Synthetic peptide located within the following region: PSPPYFGLLL ASVGRLSHYL QKGCRLSPRD TYSDRSGSSS PDSEITELKF
Species Reactivity
Human
Form/Format
Lyophilized powder
Preparation and Storage
Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20 degree C. Avoid repeat freeze-thaw cycles.
Antibody/Peptide Pairs
CTPS1 peptide (MBS3246934) is used for blocking the activity of CTPS1 antibody (MBS3222261)
Molecular Weight
65 kDa
OMIM
gene 615897

Product Categories/Family for CTPS1 blocking peptide

Peptide

Other Notes

Small volumes of CTPS1 blocking peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CTPS1 purchase

MBS3246934 is a blocking peptide targeting CTPS1. Also known as CTPS Peptide - C-terminal region. Reactive in Human.

Additional Details

NCBI/Uniprot data below describe general gene information for CTPS1. It may not necessarily be applicable to this product.

NCBI GI #
669033298
NCBI GeneID
1503
NCBI Accession #
NP_001288166.1
UniProt Primary Accession #
P17812
UniProt Related Accession #
P17812
GenBank Nucleotide #
NM_001301237.1
NCBI Official Full Name
CTP synthase 1 isoform b
NCBI Official Synonym Full Names
CTP synthase 1
NCBI Official Symbol
CTPS1
NCBI Official Synonym Symbols
CTPS; GATD5; IMD24
UniProt Protein Name
CTP synthase 1
UniProt Synonym Protein Names
CTP synthetase 1; UTP--ammonia ligase 1
Protein Family
CTP synthase
UniProt Gene Name
CTPS1
UniProt Entry Name
PYRG1_HUMAN
NCBI Protein Information
CTP synthase 1

UniProt Comments for CTPS1

CTPS: the enzyme cytidine-5-prime-triphosphate synthetase converts UTP to CTP. Important in the biosynthesis of phospholipids and nucleic acids, and plays a key role in cell growth, development, and tumorigenesis. The region to which the CTPS gene has been mapped is the location of breakpoints involved in several tumor types.

Protein type: Motility/polarity/chemotaxis; EC 6.3.4.2; Nucleotide Metabolism - pyrimidine; Ligase

Chromosomal Location of Human Ortholog: 1p34.1

Cellular Component: membrane; cytosol

Molecular Function: CTP synthase activity; ATP binding

Biological Process: T cell proliferation; B cell proliferation; response to drug; CTP biosynthetic process; nucleobase, nucleoside and nucleotide metabolic process; nucleobase, nucleoside and nucleotide interconversion; nucleobase, nucleoside, nucleotide and nucleic acid metabolic process; glutamine metabolic process

Disease: Immunodeficiency 24
Show more

Research Articles on CTPS1

1. CTP synthase forms the cytoophidium in human hepatocellular carcinoma.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with CTPS1 blocking peptide

 Products by Pathway  Pathway Diagram
 Metabolic Pathways antibodies  Metabolic Pathways Diagram
 Metabolism Pathway antibodies  Metabolism Pathway Diagram
 Metabolism Of Nucleotides Pathway antibodies  Metabolism Of Nucleotides Pathway Diagram
 Pyrimidine Metabolism Pathway antibodies  Pyrimidine Metabolism Pathway Diagram
 Pyrimidine Metabolism Pathway antibodies  Pyrimidine Metabolism Pathway Diagram
 Pyrimidine Ribonucleotide Biosynthesis, UMP => UDP/UTP,CDP/CTP Pathway antibodies  Pyrimidine Ribonucleotide Biosynthesis, UMP => UDP/UTP,CDP/CTP Pathway Diagram
 Pyrimidine Ribonucleotide Biosynthesis, UMP => UDP/UTP,CDP/CTP Pathway antibodies  Pyrimidine Ribonucleotide Biosynthesis, UMP => UDP/UTP,CDP/CTP Pathway Diagram
 Synthesis And Interconversion Of Nucleotide Di- And Triphosphates Pathway antibodies  Synthesis And Interconversion Of Nucleotide Di- And Triphosphates Pathway Diagram
 UTP And CTP De Novo Biosynthesis Pathway antibodies  UTP And CTP De Novo Biosynthesis Pathway Diagram
 UTP And CTP Dephosphorylation I Pathway antibodies  UTP And CTP Dephosphorylation I Pathway Diagram

Diseases associated with CTPS1 blocking peptide

 Disease Name  Pubmed Publications
 Cardiovascular Diseases Antibodies  >2 publications with CTPS1 and Cardiovascular Diseases
 Fibrosis Antibodies  >1 publications with CTPS1 and Fibrosis
 Liver Diseases Antibodies  >1 publications with CTPS1 and Liver Diseases
 Nervous System Diseases Antibodies  >1 publications with CTPS1 and Nervous System Diseases

Organs/Tissues associated with CTPS1 blocking peptide

 Organ/Tissue Name  Pubmed Publications
 Muscle Antibodies  >2 publications with CTPS1 and Muscle
 Blood Antibodies  >2 publications with CTPS1 and Blood
 Vascular Antibodies  >2 publications with CTPS1 and Vascular
 Liver Antibodies  >1 publications with CTPS1 and Liver
 Kidney Antibodies  >1 publications with CTPS1 and Kidney
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