EDEM3 Peptide - C-Terminal Region Blocking Peptide

Name: EDEM3 Peptide - C-Terminal Region Blocking Peptide; MyBioSource
Brand: MyBioSource
SKU: MBS3240553
Price: 195 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3240553

This is a synthetic peptide designed for use in combination with anti-EDEM3 Antibody, madeTarget Description: Quality control in the endoplasmic reticulum (ER) ensures that only properly folded proteins are retained in the cell through recognition and… More details

$195 / 0.1 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

EDEM3, Blocking Peptide

Full Product Name

EDEM3 Peptide - C-terminal region

Product Gene Name

EDEM3 blocking peptide

Product Synonym Gene Name

C1orf22

Sequence

NAASISPSEQ TSNPTENHET TNLNGECTDL DNQLQEQSET EEDSNPNVSW

Species Reactivity

Human

Form/Format

Lyophilized powder

Preparation and Storage

Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20 degree C. Avoid repeat freeze-thaw cycles.

Antibody/Peptide Pairs

EDEM3 peptide (MBS3240553) is used for blocking the activity of EDEM3 antibody (MBS3215650)

Molecular Weight

98kDa

OMIM

605466

Product Categories/Family for EDEM3 blocking peptide

Peptide

Applications Tested/Suitable for EDEM3 blocking peptide

Western Blot (WB)

Other Notes

Small volumes of EDEM3 blocking peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for EDEM3 purchase

MBS3240553 is a blocking peptide targeting EDEM3. Also known as EDEM3 Peptide - C-terminal region. Reactive in Human.

Additional Details

NCBI/Uniprot data below describe general gene information for EDEM3. It may not necessarily be applicable to this product.

NCBI GI #

94538339

NCBI GeneID

55423

NCBI Accession #

NP_001034597

UniProt Primary Accession #

Q9P1W8

UniProt Related Accession #

Q9P1W8

GenBank Nucleotide #

NM_001039508

NCBI Official Full Name

signal-regulatory protein gamma isoform 3

NCBI Official Synonym Full Names

signal regulatory protein gamma

NCBI Official Symbol

SIRPG

NCBI Official Synonym Symbols

CD172g; SIRPB2; SIRP-B2; bA77C3.1; SIRPgamma

UniProt Protein Name

Signal-regulatory protein gamma

UniProt Synonym Protein Names

CD172 antigen-like family member B; Signal-regulatory protein beta-2

Protein Family

ER degradation-enhancing alpha-mannosidase-like protein

UniProt Gene Name

SIRPG

UniProt Synonym Gene Names

SIRPB2; SIRP-gamma; SIRP-b2; SIRP-beta-2

UniProt Entry Name

SIRPG_HUMAN

NCBI Protein Information

signal-regulatory protein gamma

NCBI Summary for EDEM3

The protein encoded by this gene is a member of the signal-regulatory protein (SIRP) family, and also belongs to the immunoglobulin superfamily. SIRP family members are receptor-type transmembrane glycoproteins known to be involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]

UniProt Comments for EDEM3

SIRPG: Probable immunoglobulin-like cell surface receptor. On binding with CD47, mediates cell-cell adhesion. Engagement on T- cells by CD47 on antigen-presenting cells results in enhanced antigen-specific T-cell proliferation and costimulates T-cell activation. 4 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: 20p13

Cellular Component: membrane; plasma membrane; integral to membrane

Molecular Function: protein binding

Biological Process: negative regulation of cell proliferation; cell-cell signaling; positive regulation of cell proliferation; positive regulation of cell-cell adhesion; positive regulation of T cell activation; cell adhesion; blood coagulation; leukocyte migration

Research Articles on EDEM3

1. SIRPgamma in complex with FabOX117 forms a dimer in the crystal. Binding to the Fab fixes the position of domain 1 relative to domains 2/3 exposing a surface which favours formation of a homotypic dimer.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with EDEM3 blocking peptide

Products by Pathway	Pathway Diagram
Cell Surface Interactions At The Vascular Wall Pathway antibodies	Cell Surface Interactions At The Vascular Wall Pathway Diagram
Cell-Cell Communication Pathway antibodies	Cell-Cell Communication Pathway Diagram
Hemostasis Pathway antibodies	Hemostasis Pathway Diagram
Osteoclast Differentiation Pathway antibodies	Osteoclast Differentiation Pathway Diagram
Osteoclast Differentiation Pathway antibodies	Osteoclast Differentiation Pathway Diagram
Signal Regulatory Protein (SIRP) Family Interactions Pathway antibodies	Signal Regulatory Protein (SIRP) Family Interactions Pathway Diagram

Organs/Tissues associated with EDEM3 blocking peptide

Organ/Tissue Name	Pubmed Publications
Blood Antibodies	>3 publications with EDEM3 and Blood