HMGCS1 Immunizing Blocking Peptide

Name: HMGCS1 Immunizing Blocking Peptide; MyBioSource
Brand: MyBioSource
SKU: MBS428740
Price: 245 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS428740

MBS428740 is a blocking peptide targeting HMGCS1. Also known as HMGCS1 Immunizing Peptide. Reactive in Human. More details

$245 / 0.1 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

HMGCS1, Blocking Peptide

Full Product Name

HMGCS1 Immunizing Peptide

Product Gene Name

HMGCS1 blocking peptide

Product Synonym Names

HMGCS1; 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble); HMGCS; 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) synthase; 3-hydroxy-3-methylglutaryl-Coenzyme A synthase 1 (soluble); hydroxymethylglutaryl-CoA synthase, cytoplasmic

Sequence

ERNNLSYDCI GRLE

Species Reactivity

Human

Form/Format

100ug of dried peptide

Preparation and Storage

Shipped at ambient temperature, store at -20 degree C

Antibody/Peptide Pairs

HMGCS1 peptide (MBS428740) is used for blocking the activity of HMGCS1 antibody (MBS423645)

Molecular Weight

57,294 Da

OMIM

142940

ISO Certification

Manufactured in an ISO 9001:2008 Certified Laboratory.

Other Notes

Small volumes of HMGCS1 blocking peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for HMGCS1. It may not necessarily be applicable to this product.

NCBI GI #

148298764

NCBI GeneID

3157

NCBI Accession #

NP_002121.4

UniProt Secondary Accession #

B2RDL8

UniProt Related Accession #

Q01581

GenBank Nucleotide #

NM_002130.7

NCBI Official Full Name

hydroxymethylglutaryl-CoA synthase, cytoplasmic isoform 1

NCBI Official Synonym Full Names

3-hydroxy-3-methylglutaryl-CoA synthase 1

NCBI Official Symbol

HMGCS1

NCBI Official Synonym Symbols

HMGCS

UniProt Protein Name

Hydroxymethylglutaryl-CoA synthase, cytoplasmic

UniProt Synonym Protein Names

3-hydroxy-3-methylglutaryl coenzyme A synthase

Protein Family

Hydroxymethylglutaryl-CoA synthase

UniProt Gene Name

HMGCS1

UniProt Synonym Gene Names

HMGCS; HMG-CoA synthase

UniProt Entry Name

HMCS1_HUMAN

NCBI Protein Information

hydroxymethylglutaryl-CoA synthase, cytoplasmic

UniProt Comments for HMGCS1

HMGCS1: This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. Belongs to the HMG-CoA synthase family.

Protein type: Transferase; EC 2.3.3.10; Amino Acid Metabolism - valine, leucine and isoleucine degradation; Lipid Metabolism - synthesis and degradation of ketone bodies; Carbohydrate Metabolism - butanoate; Secondary Metabolites Metabolism - terpenoid backbone biosynthesis

Chromosomal Location of Human Ortholog: 5p14-p13

Cellular Component: cytoplasm; cytosol; nucleoplasm; nucleus; plasma membrane

Molecular Function: drug binding; hydroxymethylglutaryl-CoA synthase activity; isomerase activity; organic acid binding; protein homodimerization activity

Biological Process: brain development; cholesterol biosynthetic process; isoprenoid biosynthetic process; lipid metabolic process; liver development; male gonad development; response to drug; response to lipoprotein stimulus; response to low light intensity; response to purine; response to tellurium ion; response to vitamin E

Research Articles on HMGCS1

1. The authors report high-resolution crystal structures of the human cytosolic (hHMGCS1) and mitochondrial (hHMGCS2) isoforms in binary product complexes.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with HMGCS1 blocking peptide

Products by Pathway	Pathway Diagram
Activation Of Gene Expression By SREBF (SREBP) Pathway antibodies	Activation Of Gene Expression By SREBF (SREBP) Pathway Diagram
Butanoate Metabolism Pathway antibodies	Butanoate Metabolism Pathway Diagram
Butanoate Metabolism Pathway antibodies	Butanoate Metabolism Pathway Diagram
C5 Isoprenoid Biosynthesis, Mevalonate Pathway antibodies	C5 Isoprenoid Biosynthesis, Mevalonate Pathway Diagram
C5 Isoprenoid Biosynthesis, Mevalonate Pathway antibodies	C5 Isoprenoid Biosynthesis, Mevalonate Pathway Diagram
Cholesterol Biosynthesis Pathway antibodies	Cholesterol Biosynthesis Pathway Diagram
Cholesterol Biosynthesis Pathway antibodies	Cholesterol Biosynthesis Pathway Diagram
Endochondral Ossification Pathway antibodies	Endochondral Ossification Pathway Diagram
FOXA2 And FOXA3 Transcription Factor Networks Pathway antibodies	FOXA2 And FOXA3 Transcription Factor Networks Pathway Diagram
Fatty Acid, Triacylglycerol, And Ketone Body Metabolism Pathway antibodies	Fatty Acid, Triacylglycerol, And Ketone Body Metabolism Pathway Diagram

Diseases associated with HMGCS1 blocking peptide

Disease Name	Pubmed Publications
Liver Diseases Antibodies	>8 publications with HMGCS1 and Liver Diseases
Fatty Liver Antibodies	>8 publications with HMGCS1 and Fatty Liver
Inflammation Antibodies	>5 publications with HMGCS1 and Inflammation
Carcinoma, Hepatocellular Antibodies	>4 publications with HMGCS1 and Carcinoma, Hepatocellular
Liver Neoplasms Antibodies	>4 publications with HMGCS1 and Liver Neoplasms
Hepatitis Antibodies	>4 publications with HMGCS1 and Hepatitis
Cardiovascular Diseases Antibodies	>4 publications with HMGCS1 and Cardiovascular Diseases
Disease Models, Animal Antibodies	>4 publications with HMGCS1 and Disease Models, Animal
Weight Loss Antibodies	>3 publications with HMGCS1 and Weight Loss
Mental Disorders Antibodies	>3 publications with HMGCS1 and Mental Disorders

Organs/Tissues associated with HMGCS1 blocking peptide

Organ/Tissue Name	Pubmed Publications
Liver Antibodies	>23 publications with HMGCS1 and Liver
Blood Antibodies	>13 publications with HMGCS1 and Blood
Ovary Antibodies	>4 publications with HMGCS1 and Ovary
Lung Antibodies	>3 publications with HMGCS1 and Lung
Bone Antibodies	>3 publications with HMGCS1 and Bone
Brain Antibodies	>3 publications with HMGCS1 and Brain
Nerve Antibodies	>2 publications with HMGCS1 and Nerve
Heart Antibodies	>2 publications with HMGCS1 and Heart
Connective Tissue Antibodies	>2 publications with HMGCS1 and Connective Tissue
Mammary Gland Antibodies	>1 publications with HMGCS1 and Mammary Gland