NPY5R Peptide - N-Terminal Region Blocking Peptide

Name: NPY5R Peptide - N-Terminal Region Blocking Peptide; MyBioSource
Brand: MyBioSource
SKU: MBS3245144
Price: 195 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3245144

This is a synthetic peptide designed for use in combination with anti-NPY5R Antibody, madeTarget Description: The protein encoded by this gene is a receptor for neuropeptide Y and peptide YY. The encoded protein appears to be involved in regulating food… More details

$195 / 0.1 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

NPY5R, Blocking Peptide

Full Product Name

NPY5R Peptide - N-terminal region

Product Gene Name

NPY5R blocking peptide

Product Synonym Gene Name

NPYR5; NPY5-R; NPYY5-R

Sequence

Synthetic peptide located within the following region: DEYYNKTLAT ENNTAATRNS DFPVWDDYKS SVDDLQYFLI GLYTFVSLLG

Species Reactivity

Human

Form/Format

Lyophilized powder

Preparation and Storage

Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20 degree C. Avoid repeat freeze-thaw cycles.

Antibody/Peptide Pairs

NPY5R peptide (MBS3245144) is used for blocking the activity of NPY5R antibody (MBS3220343)

Molecular Weight

49 kDa

OMIM

602001

Product Categories/Family for NPY5R blocking peptide

Peptide

Applications Tested/Suitable for NPY5R blocking peptide

Western Blot (WB)

Other Notes

Small volumes of NPY5R blocking peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for NPY5R purchase

MBS3245144 is a blocking peptide targeting NPY5R. Also known as NPY5R Peptide - N-terminal region. Reactive in Human.

Additional Details

NCBI/Uniprot data below describe general gene information for NPY5R. It may not necessarily be applicable to this product.

NCBI GI #

5453796

NCBI GeneID

4889

NCBI Accession #

NP_006165.1

UniProt Primary Accession #

Q15761

UniProt Related Accession #

Q15761

GenBank Nucleotide #

NM_006174.3

NCBI Official Full Name

neuropeptide Y receptor type 5

NCBI Official Synonym Full Names

neuropeptide Y receptor Y5

NCBI Official Symbol

NPY5R

NCBI Official Synonym Symbols

NPYR5; NPY5-R; NPYY5-R

UniProt Protein Name

Neuropeptide Y receptor type 5

UniProt Synonym Protein Names

NPY-Y5 receptor

Protein Family

Neuropeptide Y receptor

UniProt Gene Name

NPY5R

UniProt Synonym Gene Names

NPYR5; NPY5-R; NPYY5-R; Y5 receptor

UniProt Entry Name

NPY5R_HUMAN

NCBI Protein Information

neuropeptide Y receptor type 5

NCBI Summary for NPY5R

The protein encoded by this gene is a receptor for neuropeptide Y and peptide YY. The encoded protein appears to be involved in regulating food intake, with defects in this gene being associated with eating disorders. Also, the encoded protein is involved in a pathway that protects neuroblastoma cells from chemotherapy-induced cell death, providing a possible therapeutic target against neuroblastoma. Three transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Nov 2015]

UniProt Comments for NPY5R

NPY5R: Receptor for neuropeptide Y and peptide YY. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity. Seems to be associated with food intake. Could be involved in feeding disorders. Belongs to the G-protein coupled receptor 1 family.

Protein type: Receptor, GPCR; GPCR, family 1; Membrane protein, multi-pass; Membrane protein, integral

Chromosomal Location of Human Ortholog: 4q31-q32

Cellular Component: neuron projection; integral to plasma membrane; cytoplasm; plasma membrane

Molecular Function: peptide YY receptor activity; pancreatic polypeptide receptor activity; neuropeptide Y receptor activity

Biological Process: synaptic transmission; generation of ovulation cycle rhythm; G-protein coupled receptor protein signaling pathway; negative regulation of glutamate secretion; positive regulation of acute inflammatory response; neuropeptide signaling pathway; eating behavior; positive regulation of smooth muscle cell proliferation; negative regulation of synaptic transmission, GABAergic; negative regulation of apoptosis

Research Articles on NPY5R

1. Y1R and Y5R might be the dominant receptors that mediate the effect of NPY-induced fat accumulation in both subcutaneous and visceral adipose tissues. Y1R and Y5R in visceral adipose tissue might be targets of drug development in prevention or treatment of obesity.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with NPY5R blocking peptide

Reference Product	PubMed Publications
NPY blocking peptide	>9 publications with NPY5R and NPY
PYY blocking peptide	>1 publications with NPY5R and PYY

Pathways associated with NPY5R blocking peptide

Products by Pathway	Pathway Diagram
Class A/1 (Rhodopsin-like Receptors) Pathway antibodies	Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
G Alpha (i) Signalling Events Pathway antibodies	G Alpha (i) Signalling Events Pathway Diagram
GPCR Downstream Signaling Pathway antibodies	GPCR Downstream Signaling Pathway Diagram
GPCR Ligand Binding Pathway antibodies	GPCR Ligand Binding Pathway Diagram
GPCRs, Class A Rhodopsin-like Pathway antibodies	GPCRs, Class A Rhodopsin-like Pathway Diagram
Neuroactive Ligand-receptor Interaction Pathway antibodies	Neuroactive Ligand-receptor Interaction Pathway Diagram
Neuroactive Ligand-receptor Interaction Pathway antibodies	Neuroactive Ligand-receptor Interaction Pathway Diagram
Peptide GPCRs Pathway antibodies	Peptide GPCRs Pathway Diagram
Peptide Ligand-binding Receptors Pathway antibodies	Peptide Ligand-binding Receptors Pathway Diagram
Signal Transduction Pathway antibodies	Signal Transduction Pathway Diagram

Diseases associated with NPY5R blocking peptide

Disease Name	Pubmed Publications
Obesity Antibodies	>9 publications with NPY5R and Obesity
Weight Loss Antibodies	>4 publications with NPY5R and Weight Loss
Nervous System Diseases Antibodies	>2 publications with NPY5R and Nervous System Diseases
Kidney Diseases Antibodies	>1 publications with NPY5R and Kidney Diseases
Seizures Antibodies	>1 publications with NPY5R and Seizures
Liver Diseases Antibodies	>1 publications with NPY5R and Liver Diseases
Dyslipidemias Antibodies	>1 publications with NPY5R and Dyslipidemias
Hypertension Antibodies	>1 publications with NPY5R and Hypertension
Disease Models, Animal Antibodies	>1 publications with NPY5R and Disease Models, Animal
Hypertrophy Antibodies	>1 publications with NPY5R and Hypertrophy