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PAM16 Peptide - C-Terminal Region Blocking Peptide

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3241564

This is a synthetic peptide designed for use in combination with anti-PAM16 Antibody, madeTarget Description: PAM16 regulates ATP-dependent protein translocation into the mitochondrial matrix and inhibits DNAJC19 stimulation of HSPA9/Mortalin ATPase activity. More details

$195 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
PAM16, Blocking Peptide
Full Product Name
PAM16 Peptide - C-terminal region
Product Gene Name
Product Synonym Gene Name
CGI-136; Magmas
Sequence
NYEHLFKVND KSVGGSFYLQ SKVVRAKERL DEELKIQAQE DREKGQMPHT
Species Reactivity
Human
Form/Format
Lyophilized powder
Preparation and Storage
Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20 degree C. Avoid repeat freeze-thaw cycles.
Antibody/Peptide Pairs
PAM16 peptide (MBS3241564) is used for blocking the activity of PAM16 antibody (MBS3216663)
Molecular Weight
14kDa
OMIM
613320

Product Categories/Family for PAM16 blocking peptide

Applications Tested/Suitable for PAM16 blocking peptide
Western Blot (WB)

Other Notes

Small volumes of PAM16 blocking peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PAM16 purchase

MBS3241564 is a blocking peptide targeting PAM16. Also known as PAM16 Peptide - C-terminal region. Reactive in Human.

Additional Details

NCBI/Uniprot data below describe general gene information for PAM16. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Synonym Full Names
presequence translocase associated motor 16
NCBI Official Symbol
PAM16
NCBI Official Synonym Symbols
TIM16; MAGMAS; SMDMDM; TIMM16; CGI-136
UniProt Protein Name
Mitochondrial import inner membrane translocase subunit TIM16
UniProt Synonym Protein Names
Mitochondria-associated granulocyte macrophage CSF-signaling molecule; Presequence translocated-associated motor subunit PAM16
UniProt Gene Name
PAM16
UniProt Synonym Gene Names
MAGMAS; TIM16; TIMM16
UniProt Entry Name
TIM16_HUMAN
NCBI Protein Information
mitochondrial import inner membrane translocase subunit TIM16

NCBI Summary for PAM16

This gene encodes a mitochondrial protein involved in granulocyte-macrophage colony-stimulating factor (GM-CSF) signaling. This protein also plays a role in the import of nuclear-encoded mitochondrial proteins into the mitochondrial matrix and may be important in reactive oxygen species (ROS) homeostasis. Mutations in this gene cause Megarbane-Dagher-Melike type spondylometaphyseal dysplasia, an early lethal skeletal dysplasia characterized by short stature, developmental delay and other skeletal abnormalities. [provided by RefSeq, May 2017]
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UniProt Comments for PAM16

Magmas: Regulates ATP-dependent protein translocation into the mitochondrial matrix. Inhibits DNAJC19 stimulation of HSPA9/Mortalin ATPase activity. Belongs to the TIM16/PAM16 family.

Protein type: Mitochondrial

Chromosomal Location of Human Ortholog: 16p13.3

Cellular Component: mitochondrial matrix; protein complex

Molecular Function: protein binding

Biological Process: cellular protein metabolic process; negative regulation of ATPase activity; ossification; protein import into mitochondrial matrix; protein targeting to mitochondrion

Disease: Spondylometaphyseal Dysplasia, Megarbane-dagher-melki Type
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Diseases associated with PAM16 blocking peptide

Organs/Tissues associated with PAM16 blocking peptide

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