PRSS1 Peptide - Middle Region Blocking Peptide

Name: PRSS1 Peptide - Middle Region Blocking Peptide; MyBioSource
Brand: MyBioSource
SKU: MBS3245180
Price: 195 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3245180

This gene encodes a trypsinogen, which is a member of the trypsin family of serine proteases. This enzyme is secreted by the pancreas and cleaved to its active form in the small intestine. It is active on peptide linkages involving the carboxyl group of… More details

$195 / 0.1 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

PRSS1, Blocking Peptide

Full Product Name

PRSS1 Peptide - middle region

Product Gene Name

PRSS1 blocking peptide

Product Synonym Gene Name

TRP1; TRY1; TRY4; TRYP1

Sequence

Synthetic peptide located within the following region: CYKSRIQVRL GEHNIEVLEG NEQFINAAKI IRHPQYDRKT LNNDIMLIKL

Species Reactivity

Human

Form/Format

Lyophilized powder

Preparation and Storage

Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20 degree C. Avoid repeat freeze-thaw cycles.

Antibody/Peptide Pairs

PRSS1 peptide (MBS3245180) is used for blocking the activity of PRSS1 antibody (MBS3220379)

Molecular Weight

27 kDa

OMIM

167800

Product Categories/Family for PRSS1 blocking peptide

Peptide

Applications Tested/Suitable for PRSS1 blocking peptide

Western Blot (WB)

Other Notes

Small volumes of PRSS1 blocking peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PRSS1 purchase

MBS3245180 is a blocking peptide targeting PRSS1. Also known as PRSS1 Peptide - middle region. Reactive in Human.

Additional Details

NCBI/Uniprot data below describe general gene information for PRSS1. It may not necessarily be applicable to this product.

NCBI GI #

4506145

NCBI GeneID

5644

NCBI Accession #

NP_002760.1

UniProt Primary Accession #

P07477

UniProt Related Accession #

P07477

GenBank Nucleotide #

NM_002769.4

NCBI Official Full Name

trypsin-1 preproprotein

NCBI Official Synonym Full Names

serine protease 1

NCBI Official Symbol

PRSS1

NCBI Official Synonym Symbols

TRP1; TRY1; TRY4; TRYP1

UniProt Protein Name

Trypsin-1

UniProt Synonym Protein Names

Beta-trypsin; Cationic trypsinogen; Serine protease 1; Trypsin I

Protein Family

Anionic trypsin

UniProt Gene Name

PRSS1

UniProt Synonym Gene Names

TRP1; TRY1; TRYP1

UniProt Entry Name

TRY1_HUMAN

NCBI Protein Information

trypsin-1

UniProt Comments for PRSS1

trypsin 1: Has activity against the synthetic substrates Boc-Phe- Ser-Arg-Mec, Boc-Leu-Thr-Arg-Mec, Boc-Gln-Ala-Arg-Mec and Boc-Val- Pro-Arg-Mec. The single-chain form is more active than the two- chain form against all of these substrates. Defects in PRSS1 are a cause of pancreatitis (PCTT). A disease characterized by the presence of calculi in pancreatic ducts. It causes severe abdominal pain attacks. Belongs to the peptidase S1 family.

Protein type: Protease; Secreted, signal peptide; Secreted; EC 3.4.21.4

Chromosomal Location of Human Ortholog: 7q34

Cellular Component: extracellular region

Molecular Function: metal ion binding; serine-type endopeptidase activity

Biological Process: extracellular matrix disassembly; extracellular matrix organization and biogenesis; vitamin metabolic process; cobalamin metabolic process; digestion; proteolysis; water-soluble vitamin metabolic process

Disease: Trypsinogen Deficiency; Pancreatitis, Hereditary

Research Articles on PRSS1

1. PRSS1 and SPINK1 mutations serve as genetic background for hereditary pancreatitis in Japan.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with PRSS1 blocking peptide

Products by Pathway	Pathway Diagram
Activation Of Matrix Metalloproteinases Pathway antibodies	Activation Of Matrix Metalloproteinases Pathway Diagram
Degradation Of The Extracellular Matrix Pathway antibodies	Degradation Of The Extracellular Matrix Pathway Diagram
Extracellular Matrix Organization Pathway antibodies	Extracellular Matrix Organization Pathway Diagram
Influenza A Pathway antibodies	Influenza A Pathway Diagram
Influenza A Pathway antibodies	Influenza A Pathway Diagram
Neuroactive Ligand-receptor Interaction Pathway antibodies	Neuroactive Ligand-receptor Interaction Pathway Diagram
Neuroactive Ligand-receptor Interaction Pathway antibodies	Neuroactive Ligand-receptor Interaction Pathway Diagram
Pancreatic Secretion Pathway antibodies	Pancreatic Secretion Pathway Diagram
Pancreatic Secretion Pathway antibodies	Pancreatic Secretion Pathway Diagram
Protein Digestion And Absorption Pathway antibodies	Protein Digestion And Absorption Pathway Diagram

Diseases associated with PRSS1 blocking peptide

Disease Name	Pubmed Publications
Pancreatitis Antibodies	>193 publications with PRSS1 and Pancreatitis
Pancreatitis, Chronic Antibodies	>152 publications with PRSS1 and Pancreatitis, Chronic
Hereditary pancreatitis Antibodies	>86 publications with PRSS1 and Hereditary pancreatitis
Fibrosis Antibodies	>84 publications with PRSS1 and Fibrosis
Neoplasms Antibodies	>49 publications with PRSS1 and Neoplasms
Pancreatic Neoplasms Antibodies	>38 publications with PRSS1 and Pancreatic Neoplasms
Inflammation Antibodies	>18 publications with PRSS1 and Inflammation
Carcinoma Antibodies	>16 publications with PRSS1 and Carcinoma
Immune System Diseases Antibodies	>10 publications with PRSS1 and Immune System Diseases
Gastrointestinal Diseases Antibodies	>9 publications with PRSS1 and Gastrointestinal Diseases

Organs/Tissues associated with PRSS1 blocking peptide

Organ/Tissue Name	Pubmed Publications
Pancreas Antibodies	>75 publications with PRSS1 and Pancreas
Liver Antibodies	>8 publications with PRSS1 and Liver
Muscle Antibodies	>2 publications with PRSS1 and Muscle
Heart Antibodies	>1 publications with PRSS1 and Heart
Testis Antibodies	>1 publications with PRSS1 and Testis
Prostate Antibodies	>1 publications with PRSS1 and Prostate